MI Free is dedicated to allergy to the preservative methylisothiazolinone (MI) and its relatives, such as methylchloroisothiazolinone (MCI), which are found widely in cosmetics, toiletries, household cleaning products and other products such as paints.
Full Answer
What does mi stand for?
Acronym Definition MI Michigan (US postal abbreviation) MI Mile MI Middle Initial MI Myocardial Infarction (heart attack) 72 more rows ...
Is there a fabric softener that is mi free?
Yet to find a fabric softener that is both free and smells nice, so just do without. Had a real problem with cutlery/cups washed in fairy liquid (the residue enough to set off a reaction) but much better after switching to ecover washing up liquid which they confirmed is MI/MCI free.
Should mi be added to the ingredient list?
Cosmetic regulations require the inclusion of MI in the ingredient list, but it would be much easier for the consumer if all product categories used the same system. I am also unfortunate enough to be sensitive to this ingredient, which is incredibly hard to avoid! For laundry detergent, fairy non bio powder the only one I have found.
What is MCI/MI and CMI/mi?
MCI/MI is tested as a 0.01% mix in aqueous solution. These are both included in the Australasian Standard Series. Only CMI/MI is available in the True Test Kit and one study in 2015 from Bangkok demonstrated that 27% of those positive to MI would be missed if only MCI/MI mix in aqua was tested.
What does MI free mean?
MI Free is dedicated to allergy to the preservative methylisothiazolinone (MI) and its relatives, such as methylchloroisothiazolinone (MCI), which are found widely in cosmetics, toiletries, household cleaning products and other products such as paints.
What does methylisothiazolinone do to your hair?
Methylisothiazolinone (MIT) and Methylchloroisothiazolinone (CMIT) are widely used preservatives found in liquid cosmetic and personal care products. Both chemicals inhibit bacterial growth in cosmetic products on their own, but they are most commonly used as a mixture in products.
Is methylisothiazolinone good for skin?
Takeaway. Methylchloroisothiazolinone (MCI), especially when paired with methylisothiazolinone (MI), is an effective preservative. In high concentrations it can be a skin irritant and even cause chemical burns.
Is methylisothiazolinone in laundry detergent?
Contact allergy to methylisothiazolinone (MI) was commonly attributed to the usage in cosmetics but MI is also a common preservative in household detergents and water-based paint [1].
What shampoos do not contain methylisothiazolinone?
5 Best Methylisothiazolinone- and Methylchloroisothiazolinone-Free Bath ProductsNatural Shampoo. 100% Pure. Burdock & Neem Healthy Scalp Shampoo. ... Gentle Shampoo Concentrate. Clean Clean. Restorative Hair Wash Concentrated. ... Shower Gel for Sensitive Skin. 100% Pure. ... Sulfate-Free Body Wash. Ursa Major. ... Vegan Conditioner. Yarok.
Does Dove soap contain methylisothiazolinone?
NOT SAFE - USA 2016 - All of the Dove body washes contain MI, even the "Sensitive" version. Their solid soap bars are ok though.
Should I avoid methylisothiazolinone?
If you or a family member has sensitive skin, you should especially avoid products that contain both CMIT and MIT. For babies and young children, be aware that methylisothiazolinone may be in baby soaps, shampoos and even baby wipes that have been labeled “hypoallergenic” or “natural”.
Does CeraVe contain methylisothiazolinone?
Upon further investigation, both CeraVe sunscreens were found to contain MI.
What are the side effects of methylisothiazolinone?
It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. The American Contact Dermatitis Society named Methylchloroisothiazolinone the Contact Allergen of the Year for 2013.
Is methylisothiazolinone in toilet paper?
Methylchloroisothiazolinone/methylisothiazolinone is a common preservative in moist toilet paper.
What products have no methylisothiazolinone?
Vanicream. Neutrogena. La Roche-Posay. CeraVe.Wellness Markers. Top Allergen Free. Common Preservative Free. Fragrance Free. Irritant Free. Teen Safe. Baby SAFE. Eyelid Safe. Common Preservative Free. Topical Antibiotic Free. MCI/MI Free. Balsam of Peru Free. Top Allergen Free. Common Preservative Free. Fragrance Free.
What is another name for methylisothiazolinone?
Trade names for MCI/MI include Kathon®, Kathon CG®, Kathon 886®Euxyl K100, Acticide, Algucid, Algucid CH 50, Amerstat 250, GR 856,Groton TK2, Metatin GT, Mitco CC, Mx 323 Parmetol.
How does it work?
Both MCI and MI are ‘isothiazolinones’. The mechanism by which they inhibit microbial growth is complex, and not yet fully understood.
Are there any risks?
For a while Kathon CG was seen the ideal preservatives as they work extremely well at astonishingly low levels.
Regulation and controversy
Kathon CG was first regulated in the European Union in 2004 with the ‘Scientific Committee on Consumer Safety’ (SCCS) stating that at maximum concentrations of 0.01% MI would not pose a risk to human health [7]. This was revised in 2009 to 0.0015% for combination products – a significant reduction [8].
Alternatives to Kathon CG
Kathon CG can cause severe allergic contact dermatitis, but it’s also an extremely cheap and effective preservative. This is part of the reason why leading brands were initially hesitant to replace it. Ironically Kathon-CG was gradually replaced by Parabens until they courted their own controversy.
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What is MI used for?
MI was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI). Since 2005, it has been widely used in cosmetics and household products, such as moist wipes, shampoos, cleaners and liquid laundry products. When used in the industrial setting, ...
When was MI banned?
The European Scientific Committee on Consumer Safety reviewed the literature and in July 2015 banned the use of MI in Europe in all-new leave-on products and lowered the concentration for rinse-off products; the concentration is now so low that it no longer functions as a preservative, and probably will not be used.
Can you self test for MI?
Self-testing a product for MI is possible but should be done only after first talking with your dermatologist. An open application test should be done only with products that are designed to stay on the skin such as cosmetics (not including eyeliners or mascaras) and lotions.
What is MI in medical terms?
Terminology. Main article: Acute coronary syndrome. Myocardial infarction (MI) refers to tissue death ( infarction) of the heart muscle ( myocardium) caused by ischaemia, that is lack of oxygen delivery to myocardial tissue.
What age does a person with ischemic heart disease have to be to get MI?
Family history of ischemic heart disease or MI, particularly if one has a male first-degree relative (father, brother) who had a myocardial infarction before age 55 years, or a female first-degree relative (mother, sister) less than age 65 increases a person's risk of MI.
What is a myocardial infarction?
A myocardial infarction occurs when an atherosclerotic plaque slowly builds up in the inner lining of a coronary artery and then suddenly ruptures, causing catastrophic thrombus formation, totally occluding the artery and preventing blood flow downstream. A myocardial infarction ( MI ), commonly known as a heart attack, ...
How many people have myocardial infarctions in 2015?
Worldwide, about 15.9 million myocardial infarctions occurred in 2015. More than 3 million people had an ST elevation MI, and more than 4 million had an NSTEMI. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States.

What Is Mi/Mci?
How Does It Work?
- Both MCI and MI are ‘isothiazolinones’. The mechanism by which they inhibit microbial growth is complex, and not yet fully understood. A comprehensive study in 2007 evaluated a number of biochemical characteristics, and observed that isothiazolinones inhibited microbial activity within minutes, and caused cell death after several hours of exposure . Interestingly, both MCI and MI a…
Are There Any Risks?
- For a while Kathon CG was seen the ideal preservativesas they work extremely well at astonishingly low levels. However, in the early 2000s a number of studies indicated that Kathon CG probably wasn’t as safe as previously thought [4, 5]. The main concern raised was the growing incidence of allergic contact dermatitis in Europe and the United States (US). Those affected rep…
Regulation and Controversy
- Kathon CG was first regulated in the European Union in 2004 with the ‘Scientific Committee on Consumer Safety’ (SCCS) stating that at maximum concentrations of 0.01% MI would not pose a risk to human health . This was revised in 2009 to 0.0015% for combination products – a significant reduction . The huge controversy surrounding Kathon CG came in in the UK in mid-20…
Alternatives to Kathon Cg
- Kathon CG can cause severe allergic contact dermatitis, but it’s also an extremely cheap and effective preservative. This is part of the reason why leading brands were initially hesitant to replace it. Ironically Kathon-CG was gradually replaced by Parabensuntil they courted their own controversy. The problem manufacturers face is there are very few cheap, effective, and odourle…
References
- Wilkinson, J. D., Shaw, S., Andersen, K. E., Brandao, F. M., Bruynzeel, D. P., Bruze, M., & Goossens, A. (2002). Monitoring levels of preservative sensitivity in Europe. Contact Dermatitis, 46(4), 207-210. Lundov, M. D., Krongaard, T., Menné, T. L., & Johansen, J. D. (2011). Methylisothiazolinone contact allergy: a review. British Journal of Dermatology, 165(6), 1178-1182. Ferrarese, L., Paglia…