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what happens if mmr vaccine is administered intramuscularly

by Tomas Willms Published 3 years ago Updated 2 years ago

All live injected vaccines (MMR, varicella, and yellow fever) are recommended to be given subcutaneously. However, intramuscular administration of any of these vaccines is not likely to decrease immunogenicity, and doses given IM do not need to be repeated.Oct 22, 2020

What happens if you give MMR vaccine intramuscular?

Since then, data have shown that administration of MMR vaccine by IM injection generates an immune response equal to the response when the vaccine is given via the SC route, and the vaccine is also well-tolerated.

Is MMR given subcutaneously or intramuscular?

Administering the MMR Vaccine Both vaccines are administered by the subcutaneous route. The minimum age for both MMR and MMRV is 12 months of age. The typical age for the second dose of either vaccine is at 4 to 6 years of age.

What happens if varicella vaccine is administered intramuscularly?

Response to vaccines recommended by the subcutaneous route is unlikely to be affected if the vaccines are administered by the intramuscular rather than subcutaneous route. Repeating doses of vaccine administered by the intramuscular route when recommended to be by the subcutaneous route is not necessary (10).

Why Measles vaccine is given subcutaneously?

In general, vaccines containing adjuvants (a component that enhances the antigenic response) are administered IM to avoid irritation, induration, skin discoloration, inflammation, and granuloma formation if injected into subcutaneous tissue.

What is the route of administration for MMR?

Each 0.5 mL dose is administered subcutaneously. The first dose is administered at 12 to 15 months of age. A second dose is administered at 4 to 6 years of age.

Is ProQuad subcutaneous or IM?

ProQuad® is a vaccine indicated for active immunization for the prevention of measles, mumps, rubella, and varicella in children 12 months through 12 years of age. Each 0.5-mL dose of ProQuad is administered subcutaneously.

Is MMR a live vaccine?

Two doses of MMR vaccine are 97% effective against measles and 88% effective against mumps. MMR is an attenuated (weakened) live virus vaccine. This means that after injection, the viruses cause a harmless infection in the vaccinated person with very few, if any, symptoms before they are eliminated from the body.

At what angle do you give an IM injection?

Insert needle at a 90o angle to the skin with a quick thrust. Retain pressure on skin around injection site with thumb and index finger while needle is inserted. Aspiration is not necessary. Multiple injections given in the same extremity should be separated as far as possible (preferably at least 1” apart).

Can MMR and varicella be given in same leg?

MMR and varicella vaccine can be administered simultaneously (7). Live, attenuated influenza vaccine (LAIV) does not interfere with the immune response to MMR or varicella vaccines administered at the same visit (18).

Where is the MMR vaccine given?

The MMR vaccine is given as 2 doses of a single injection into the muscle of the thigh or upper arm. 2 doses of the vaccine are needed to ensure full protection.

Which of the following is a contraindication to administration of MMR vaccine?

Contraindications for MMR vaccination include history of a severe (anaphylactic) reaction to a previous dose or to any component of the vaccine (such as gelatin or neomycin), pregnancy and immunosuppression.

How do you give an intramuscular injection?

Hold it firmly about an inch away (2.54 cm) from the muscle. In the other hand, hold the needle at a 90-degree angle and insert it quickly and deeply enough to penetrate your muscle. Inject the medication. If there is no blood in the syringe, push on the plunger to inject the medication slowly into the muscle.

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