What is Swiss-Prot?
Swiss-Prot is a manually curated biological database of protein sequences. Swiss-Prot was created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute.
What is UniProtKB/SWISS-PROT?
UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis. The aim of UniProtKB/Swiss-Prot is to provide all known relevant information about a particular protein.
What is UniProt?
UniProt. UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
What is Swissport?
Swissport International Ltd. is a Chinese-owned aviation services company providing airport ground and cargo handling services.
What is SWISS-PROT?
SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, structure of its domains, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases.
What is SWISS-PROT Wikipedia?
UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis.
Who created SWISS-PROT?
SWISS-PROT (1) is an annotated protein sequence database, which was created at the Department of Medical Biochemistry of the University of Geneva and has been a collaborative effort of the Department and the European Molecular Biology Laboratory (EMBL), since 1987.
Is SWISS-PROT the same as UniProt?
Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. UniProtKB/Swiss-Prot is now the reviewed section of the UniProt Knowledgebase.
When was SWISS-PROT established?
SWISS-PROT ( 1 ) is an annotated protein sequence database established in 1986 and maintained collaboratively, since 1987, by the Department of Medical Biochemistry of the University of Geneva and the EMBL Data Library (now the EMBL Outstation-The European Bioinformatics Institute; 2 ).
Is SWISS-PROT a secondary database?
Complete answer: SWISS PROT is a protein sequence database. Annotations in the database provide all the information regarding the structure and function of a particular protein along with its functions and modifications if any. The data is all primary and easily accessible.
Who maintains SWISS-PROT?
1. Swiss-Prot and TrEMBL. SWISS-PROT is a protein sequence database containing detailed annotations. It was established in 1986 and jointly maintained by the department of medical biochemistry of the University of Geneva and the EMBL data library (now EBI) since 1987.
What is the difference between SWISS-PROT and TrEMBL?
TrEMBL consists of entries in a SWISS-PROT format that are derived from the translation of all coding sequences in the EMBL nucleotide sequence database, that are not in SWISS-PROT. Unlike SWISS-PROT entries those in TrEMBL are awaiting manual annotation.
Which is the best annotated database?
Among all protein sequence databases, UniProt (UniProt Consortium, 2011) is the most widely used one. It provides more annotations than any other sequence database with a minimal level of redundancy through human input or integration with other databases.
Is Swiss-Prot manually annotated?
The Swiss-Prot section of the UniProt KnowledgeBase (UniProtKB/Swiss-Prot) contains publicly available expertly manually annotated protein sequences obtained from a broad spectrum of organisms.
What does UniProt stand for?
The Universal Protein ResourceThe Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
How many proteins are in UniProt?
UniProt release 2020_04 contains over 189 million sequence records (Figure 1), with >292 000 proteomes, the complete set of proteins believed to be expressed by an organism, originating from completely sequenced viral, bacterial, archaeal and eukaryotic genomes available through the UniProtKB Proteomes portal (https:// ...
What is Swissport International?
Swissport International Ltd. is an aviation services company providing airport ground and cargo handling services owned by an international group of investors. It is headquartered in Opfikon, Switzerland. It handles around 282 million passengers and 4.8 million tonnes of cargo annually, on behalf of some 850 client-companies in the aviation sector.
When was Swissport founded?
The company was founded in 1996 as Swissair Ground Services International, independent of the former Swissair. In the following years, the company expanded both through organic growth and through various acquisitions. As part of the Swissair financial crisis, Swissport was first purchased by the British private equity firm Candover Investments and in August 2005 by the Spanish construction company Ferrovial. In the meantime, the company has grown through various acquisitions. At the end of 2010, Ferrovial sold Swissport for €654 million to the French private equity firm PAI Partners.
What awards does Swissport have?
Over the years, Swissport has been the recipient of several industry awards including Ground Handling Award 2013, Air Cargo Handling Agent of the Year 2014 (for the sixth year in succession) and Global Aviation Ground Services Company 2012 (for the twelfth year in succession).
How many employees will Swissport cut in 2020?
On June 25, 2020, Swissport UK & Ireland announced to cut a workforce of 8,500 by 50%.
Who bought Swissport?
As part of the Swissair financial crisis, Swissport was first purchased by the British private equity firm Candover Investments and in August 2005 by the Spanish construction company Ferrovial. In the meantime, the company has grown through various acquisitions.
Is Swissport a 100% shareholder in Aerocare?
Swissport now holds 100% of Aerocare, the leading Aviation Services and Airport Infrastructure Services provider in Australia/ New Zealand. On June 8, 2020, Swissport's Belgian subsidiary declared bankruptcy, which was confirmed by the Belgian commercial courts the following day.
What is Swiss Prot?
UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator -evaluated computational analysis. The aim of UniProtKB/Swiss-Prot is to provide all known relevant information about a particular protein. Annotation is regularly reviewed to keep up with current scientific findings. The manual annotation of an entry involves detailed analysis of the protein sequence and of the scientific literature.
Who is Uniprot funded by?
UniProt is funded by grants from the National Human Genome Research Institute, the National Institutes of Health (NIH), the European Commission, the Swiss Federal Government through the Federal Office of Education and Science, NCI-caBIG, and the US Department of Defense.
What is a UniProt reference cluster?
The UniProt Reference Clusters (UniRef) consist of three databases of clustered sets of protein sequences from UniProtKB and selected UniParc records. The UniRef100 database combines identical sequences and sequence fragments (from any organism) into a single UniRef entry. The sequence of a representative protein, the accession numbers of all the merged entries and links to the corresponding UniProtKB and UniParc records are displayed. UniRef100 sequences are clustered using the CD-HIT algorithm to build UniRef90 and UniRef50. Each cluster is composed of sequences that have at least 90% or 50% sequence identity, respectively, to the longest sequence. Clustering sequences significantly reduces database size, enabling faster sequence searches.
What is UniProt consortium?
The UniProt consortium comprises the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). EBI, located at the Wellcome Trust Genome Campus in Hinxton, UK, hosts a large resource of bioinformatics databases and services.
What is UniProt database?
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
When was Uniprot created?
The consortium members pooled their overlapping resources and expertise, and launched UniProt in December 2003.
Where is PIR located?
PIR, hosted by the National Biomedical Research Foundation (NBRF) at the Georgetown University Medical Center in Washington, DC, US, is heir to the oldest protein sequence database, Margaret Dayhoff 's Atlas of Protein Sequence and Structure, first published in 1965.
Focus on the group's mission
The Swiss-Prot team excels in the art of generating machine-readable knowledge of biology from the ever growing body of scientific publications. It is harnessing the power of deep learning to accelerate literature triage and information extraction, thus delivering the most accurate and informative evidence to users in a timely manner.
Biocuration and software development
We organize, clean & control the quality of your datasets for subsequent analysis. In addition, we can process, transform and align your datasets to existing standards and make them available as a database. We can propose different data storage solutions depending on project needs (e.g. federated versus integrated).
Supporting AI with machine-readable biological knowledge
Knowledgebases like UniProtKB are an essential part of the AI ecosystem; the collective biological knowledge they contain, in the form of pathways, ontologies and networks, can be used to create generalizable and interpretable models that reveal actionable biological mechanisms.
Publications
Parit Bansal, Anne Morgat, Kristian B Axelsen, Venkatesh Muthukrishnan, Elisabeth Coudert, Lucila Aimo, Nevila Hyka-Nouspikel, Elisabeth Gasteiger, Arnaud Kerhornou, Teresa Batista Neto, Monica Pozzato, Marie-Claude Blatter, Alex Ignatchenko, Nicole Redaschi, Alan Bridge. Rhea, the reaction knowledgebase in 2022.
What is Swiss Prot?
SWISS-PROT (Bairoch and Apweiler, 1996) is an annotated protein sequence database established in 1986 and maintained collaboratively, since 1987, by the Department of Medical Biochemistry of the University of Geneva and the EMBL Data Library. It is a curated protein sequence database, which strives to provide a high level of annotation (such as the description of the function of a protein, its domain structure, posttranslational modifications and variants), a minimal level of redundancy, and a high level of integration with other databases. TrEMBL is a computer-annotated supplement of SWISS-PROT that contains all the translations of EMBL nucleotide sequence entries, which are not yet integrated in SWISS-PROT. Currently, SWISS-PROT and TrEMBL have 0.5 and 7.6 million sequences, respectively. These databases are freely available at http://www.expasy.org/sprot/ and http://www.ebi.ac.uk/swissprot/.
Is SwissProt cross referenced?
SwissProt contains high-quality annotation, is nonredundant and is cross-referenced to several other databases, notably the EMBL, PROSITE pattern database and PDB.