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swiss prot ppt

by Alberto Kovacek Published 4 years ago Updated 3 years ago

What is SWISS-PROT in bioinformatics?

SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases.

How do you use SWISS-PROT?

SWISS-PROT provides detailed annotation information on protein sequences. Annotation include information on protein function, post-translational modification of proteins, domains and binding sites, secondary structures, quaternary structures, and diseases associated with protein deficiency.

What is the difference between SWISS-PROT and TrEMBL?

TrEMBL consists of entries in a SWISS-PROT format that are derived from the translation of all coding sequences in the EMBL nucleotide sequence database, that are not in SWISS-PROT. Unlike SWISS-PROT entries those in TrEMBL are awaiting manual annotation.

What is UniProt database?

The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).

Is SWISS-PROT a secondary database?

Complete answer: SWISS PROT is a protein sequence database. Annotations in the database provide all the information regarding the structure and function of a particular protein along with its functions and modifications if any. The data is all primary and easily accessible.

Is SWISS-PROT redundant?

Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions.

Is UniProt and SWISS-PROT same?

UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.

Is SWISS-PROT manually annotated?

The Swiss-Prot section of the UniProt KnowledgeBase (UniProtKB/Swiss-Prot) contains publicly available expertly manually annotated protein sequences obtained from a broad spectrum of organisms.

Which computer is annotated supplement to SWISS-PROT?

SP-TREMBLFor SP-TREMBL to act as a computer-annotated supplement to SWISS-PROT, new procedures have been introduced whereby valuable annotation has been added automatically. First, all TrEMBL entries are scanned for all PROSITE (5) patterns compatible with their taxonomic range.

What is Swiss-Prot Wikipedia?

UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis.

Why is UniProt important?

UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.

Is UniProt a secondary database?

Hybrid databases and families of databases Many data resources have both primary and secondary characteristics. For example, UniProt accepts primary sequences derived from peptide sequencing experiments.

Recommended

1. 10/18/2017 1 Swiss-Prot Protein Database Dr. Ayaz Ahmad What is Swiss-Prot? • Annotated sequence database established in 1986 • Consists of sequence entries of different line formats • Similar format to European Bioinformatics Institute Nucleotide Sequence Database (EMBL)

Swiss prot protein database

1. 10/18/2017 1 Swiss-Prot Protein Database Dr. Ayaz Ahmad What is Swiss-Prot? • Annotated sequence database established in 1986 • Consists of sequence entries of different line formats • Similar format to European Bioinformatics Institute Nucleotide Sequence Database (EMBL)

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