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expasy

by Miss Tanya Olson III Published 3 years ago Updated 3 years ago

What is ExPASy used for?

It is an extensible and integrative portal which provides access to over 160 databases and software tools, developed by SIB Groups and supporting a range of life science and clinical research domains, from genomics, proteomics and structural biology, to evolution and phylogeny, systems biology and medical chemistry.

What is ExPASy translate?

Translate is a tool which allows the translation of a nucleotide (DNA/RNA) sequence to a protein sequence.

What is UniProt in biology?

The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).

What databases are available via ExPASy?

It provides access to a variety of databases and analytical tools dedicated to proteins and proteomics. ExPASy databases include SWISS-PROT and TrEMBL, SWISS-2DPAGE, PROSITE, ENZYME and the SWISS-MODEL repository.

Which tool is accessed by ExPASy platform?

The protease digestibility prediction tool in ExPASy is called PeptideCutter,8 which can be accessed directly at http://web.expasy.org/peptide_cutter/.

How many open reading frames are in DNA?

six different reading framesSo it's actually six different reading frames for every piece of DNA, which might give you an open reading frame.

What is the function of UniProt?

The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

Why is UniProt important?

UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.

What is the difference between UniProt and Swiss-Prot?

Protein families and groups of proteins are continuously reviewed to keep up with current scientific findings. UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.

What are the 6 reading frames?

Every region of DNA has six possible reading frames, three in each direction. The reading frame that is used determines which amino acids will be encoded by a gene.... atg ccc aag ctg aat agc gta gag ggg ttt tca tca ttt gag gac gat gta taa. ... tgc cca agc tga ata gcg tag agg ggt ttt cat cat ttg agg acg atg tat.More items...

What is blast and how is it used?

BLAST is an acronym for Basic Local Alignment Search Tool and refers to a suite of programs used to generate alignments between a nucleotide or protein sequence, referred to as a “query” and nucleotide or protein sequences within a database, referred to as “subject” sequences.

What is Swiss Prot database?

SWISS-PROT (1) is an annotated protein sequence database, which was created at the Department of Medical Biochemistry of the University of Geneva and has been a collaborative effort of the Department and the European Molecular Biology Laboratory (EMBL), since 1987.

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