Is distilled water the same as water for injection?
Yes, water for injection (WFI) has a set of specifications and the manufacturer is regulated to ensure that the WFI is manufactured according to the specification. Distilled water, as far as I remember, does not have a specification and it not used directly in patient.
Is distilled water used in injection molding?
Yes, water for injection (WFI) has a set of specifications and the manufacturer is regulated to ensure that the WFI is manufactured according to the specification. Distilled water, as far as I remember, does not have a specification and it not used directly in...
What type of water is used for injections?
, Clinician and government officer. Distilled is clear from electrolytes like sodium and chloride but it might contain micro organisms or fragments of microorganisms that d make them unsuitable for injecting. Water for injection is distillerd water, however, it should be sterile and pyrogens free.
What happens if you inject distilled water into your body?
It’s referred to as isotonic, meaning it doesn’t have too much salt (hypertonic) or too little (hypotonic). It’s just right. If you injected distilled water, which is hypotonic, it would cause cells lining the blood vessels to swell and possibly rupture, as well as blood cells too.
Why is distilled water used in injections?
If it is given by injection into a vein without making it approximately isotonic, breakdown of red blood cells may occur. This can then result in kidney problems. Excessive amount may also result in fluid overload. Water for injection is generally made by distillation or reverse osmosis.
What happens when you inject distilled water?
Giving large amounts of pure water directly into a vein would cause your blood cells to become hypotonic, possibly leading to death.
What is the difference between distilled water and water for injection?
Water for injection is basically sterile, nonpyrgenic and with absence of particles. Sterile distilled water may contain pyrogens and other nonviable particles that may be harmful while administration i.v.
Can I use distilled water instead of sterile water?
Is sterile water the same as distilled water? No, sterile water should not be confused with distilled water. Distilled water is created by a process of steaming and condensation, and does not contain any minerals like salt, calcium or iron. A distinction should further be made between sterile water and saline solution.
Can you inject water into your body?
False. Use a sterile liquid: water or saline. Both tap and toilet water are not safe to inject into your blood.
Can sterile water be used for injection?
Sterile water for injection vials are primarily used to reconstitute medications available as lyophilized powders. While the prescribing information for some medications may indicate alternative sterile liquids for reconstitution, most specify that SW for injection must be used.
Is boiled water the same as distilled water?
No, they aren't the same. Boiled water is simply water that has had the temperature increased until it reaches its boiling point. This kills a host of bacteria that can make a person sick. Distilled water is water that has been stripped of all impurities, including minerals and microorganisms.
What is distilled water used for in pharmacy?
In pharmaceutical manufacturing, it is important that high purity water is used because contaminants in tap water could interfere with other ingredients and cause a chemical reaction. In this industry, distilled water is used in products like: Analytical reagents. Active pharmaceutical ingredients.
Can you buy distilled water at a pharmacy?
Distilled Water for Consumer Purchase Distilled water is available for consumers to buy at many large supermarkets, pharmacies and online from sites like Amazon and eBay.
How long does distilled water stay sterile?
Distilled water will last indefinitely if it is stored correctly and no contaminants come into contact with the water. Bottled distilled water usually comes with a best-before date. As long as you have stored the water properly, it should still be good to use even past this date.
Can normal saline be used as water for injection?
Do NOT use 0.9% sodium chloride in place of sterile water for injection (unless directed in the prescribing information) to reconstitute medications, which can result in hyperosmotic solutions at or near the saturation point and cause crystallization or infusion site reactions.
What is water for injection?
Water for injection. Water for injection is water of extra high quality without significant contamination. A sterile version is used for making solutions that will be given by injection. Before such use other substances generally must be added to make the solution more or less isotonic. It can be given by injection into a vein, muscle, ...
How is water made for injections?
Water for injection is generally made by distillation or reverse osmosis. It should contain less than a mg of elements other than water per 100 ml. Versions with agents that stop bacterial growth are also available. It is on the World Health Organization's List of Essential Medicines.
What is H2O water?
H 2 O. Water for injection is water of extra high quality without significant contamination. A sterile version is used for making solutions that will be given by injection. Before such use other substances generally must be added to make the solution more or less isotonic. It can be given by injection into a vein, muscle, or under the skin.
Can a non-sterile syringe be used in manufacturing?
A non-sterile version may be used in manufacturing with sterilization occurring later in the production process . If it is given by injection into a vein without making it approximately isotonic, breakdown of red blood cells may occur. This can then result in kidney problems.
How is steam purified?
The steam is purified using centrifugal and gravity separation methods. This equipment produces dry, saturated steam to be used as sterilizing agent. Naturally, the Pure Steam, when condensed through a Double Tube Sheet condenser, meets the requirements of international pharmacopoeias for Water for Injection.
What is STMC water?
STMC, improperly called thermocompressor or thermal recompression still, produces Water for Injection, the reliable compendial distilled water for pharmaceutical applications.
What are the factors that determine the success of a pharmaceutical process?
quality factors (such as the sterility, elimination of the pyrogens and of the chlorine solvents with low molecular weight) economical factors (low running costs) are critical for the success of the pharmaceutical process.
How is condensation achieved?
Condensation is achieved by means of the thin-falling film technology. The process is repeated in each column: the higher the quantity of columns the lower overall the consumption of the equipment. The quantity of columns therefore does not influence the quality nor the output of the equipment.
Can a STMC distiller produce hot or cold?
The STMC distiller can produce both cold Distillate or hot Distillate with huge savings of energy costs and with no need of cooling water. STMC vapor compression distillers operate with electrical heating (STMC EL) or plant steam heating (STMC ST) or even through both electrical and steam heating systems (STMC ES).
What is distilled water?
Distilled water is a water that consists only of pure water. In other words it does not contain any minerals and microelements. By the osmosis phenomenon, distilled water would flow rapidly into cells, diluting all your microelements and minerals and devastating your organism.
What is the effect of infusion of water?
The effect an infusion of water would be to cause water movement out of circulation and into your cells. If cells are n. Continue Reading. Normal saline (0.9% sodium chloride solution) is what we call isotonic, meaning it has the same concentration of sodium and other solutes as your body fluids.
Is 0.9% saline isotonic?
0. 9% saline is isotonic to the cells … it neither creates an inflow of water or outflow of water from the Red Cell. Distilled water may lyse some red cells at the point of entry and that may lead a doctor down a wrong road if he orders a lab test that picks up on the hemolysis in the blood.
Does saline infusion cause fluid movement?
Since water moves from an area of lower concentration to an area of higher concentration, an infusion of normal saline will not result in changes in fluid movement into or out of your bloodstream and cells. Water is hypotonic, meaning the concentration of dissolved solutes is less than that of your body fluids and cells.
Is water hypotonic or hypotonic?
Continue Reading. Not really. Pure water is by definition ‘hypotonic’, and thus infusing a significant amount will dilute the plasma (the fluid around blood cells), making it more hypotonic compared to the fluid inside the cells. This will lead to water entering the cells down the osmotic gradient, making then swell, ...
Is saline a salt solution?
Saline is a balanced salt solution that matches the salt concentration in a person’s cells. It’s referred to as isotonic, meaning it doesn’t have too much salt (hypertonic) or too little (hypotonic). It’s just right.
Is distilled water hypotonic?
It’s just right . If you injected distilled water, which is hypotonic, it would cause cells lining the blood vessels to swell and possibly rupture, as well as blood cells too. Too much of this can cause blood clots, which is a known risk for death. In short, it wouldn’t be good and could be very bad . 11.8K views.
What is the difference between distilled water and water for injection?
The difference between the distilled water (DW) and water for injection (WFI) is mainly based on their physical, chemical and microbiological properties. A typical distilled water system consists of various stages, each one is designed for further purification of water. The first step is known. as "pretreatment" and the aim ...
What is sterile water for injection?
Sterile water for Injection is Sterilized Pyrogens free water commonly used in Compounding of Parenteral products or small Lab. batches where no terminal sterilization is required. Water for Injection, USP; on the other hand is Pyrogens free water for use in large scale manufacturing, where the final product is terminal sterilized accordingly.
What is WFI water?
Bacteriostatic Water for Injection, USP is a sterile, nonpyrogenic preparation of water for injection containing 0.9% (9 mg/mL) of benzyl alcohol added as a bacteriostatic preservative.
What is a sterile diluent?
It is used for extemporaneous prescription compounding and as a sterile diluent for parenteral products. It may also be used for other applications where bulk Water for Injection or Purified Water is indicated but access to a validated water system is not practical, or where only a relatively small quantity is needed.
Is WFI sterile?
WFI has the highest purity possible and it is sterile. It is mainly used as a medium in the preparation of injection solutions. and must therefore. have the highest level of chemical purity and must be completely sterile.
Sterile Water for Injection 100ml - Tray of 25
Hospira Sterile Water for Injection is a nonpyrogenic solution that is used to dilute or dissolve drugs prior to injection. This preservative-free ...
Sterile Water for Injection 10ml - Single Vial
Hospira Sterile Water for Injection 10ml is a sterile, nonpyrogenic preparation of water for injection which does not contain bacteriostatic (added...
Sterile Water for Injection 20ml - Single Vial
Sterile Water for injection 20ml is a sterile, single-dose, non-pyrogenic water designed for injection. Sterile water for injection is used to diss...
Sterile Water for Injection 50ml - Single Vial
Hospira 50 mL Sterile Water for Injection is a sterile, single-dose packaged in a larger 50ml plastic vial. Sterile Water for injection is designed...
Sterile Water for Injection IV Solution Bag 1000ml
Sterile Water 1000mg IV bag used for intravenous use. Sterile water iv solution is a sterile, nonpyrogenie solution. Single-use container. DEHP fre...
Sterile Water for Irrigation 500ml Bottle, Distilled
500ml Sterile Water for Irrigation USP is sterile, distilled, non-pyrogenic water for irrigation intended only for external use for washing, rinsin...
Sterile Water for Irrigation with Screw Top
Sterile Water for Irrigation USP is topical water used for skin irrigation (rinsing), moisten wound care dressings and other medical devices from t...
What is USP sterile water?
Sterile Water for Injection, USP is sterile, nonpyrogenic, distilled water in a Pharmacy Bulk Package. A Pharmacy Bulk Package is a container of a sterile preparation for parenteral use that contains many single doses. The contents are intended for use in a pharmacy admixture program and are restricted to the preparation of admixtures for intravenous infusion. No antimicrobial or other substance has been added. pH 5.5 (5.0 to 7.0). Osmolarity O mOsmol/L (calc.).
What is USP water?
Sterile Water for Injection, USP, is sterile, nonpyrogenic, distilled water in a single dose container for intravenous administration after addition of a suitable solute. It may also be used as a dispensing container for diluent use. No antimicrobial or other substance has been added. The pH is 5.5 (5.0 to 7.0). The osmolarity is 0.
Guest Guest
I make my own distilled water with a table top distiller and have never had any problems with it. I boil it again when it is mixed with the powder in the spoon just to disslove the powder but I think it is about as pure as you will get it after it has been distilled.
Guest Guest
The stuff from the store should be fine, I cannot buy distilled water in the Uk which is why I make it myself.
Triple7 Gold Member
Pherhaps you can get distilled water for contact lenses?? Aren't they kept in 100% distilled water??
Alfa Productive Insomniac Staff Member Administrator
There is a difference between distilled water for consumption and for cleaning and ironing, etc. You need distilled water for consumption. It should be easely available from the pharmacist or other stores.
magicmaster141 Newbie
How safe is bottled water compared to disstilled? Seems like it would be pretty clean to me maybe boil it 1st to be safe? I've always used bottled water and never had a prob but I'm wondering how safe it is.
Guest Guest
Bottled water still contains minerals and other tiny particles and debris that are no visible to the human eye. Normal kitchen water filters are not good enough in removing these - why take the risk when distilled water is safer and easy to make / buy?
asystole Newbie
Even distilled water is pretty dangerous, I would never go mainline with anything other than sterile saline. Here in Canada, you can get single use 10mL normal saline (0.9% isotonic solution w/o preservatives) for like $0.50 a pop. Ask around with the pharmacists, just say it's to keep in your first aid kit for eye flushing or something.