Precautions
Warnings
- Patients with kidney disease or diabetes may not be able to take Carafate. ...
- If you have diabetes, your healthcare provider will monitor you for episodes of low blood sugar (hypoglycemia) that can happen when you are taking Carafate.
- Carafate can affect how your body absorbs certain medications. ...
How long should I take Carafate?
teaspoonfuls) four times per day. CARAFATE should be administered on an empty stomach. Antacids may be prescribed as needed for relief of pain but should not be taken within one-half hour before or after sucralfate. While healing with sucralfate may occur during the first week or two, treatment should be continued for
When should Carafate be administered?
What Conditions does SUCRALFATE Treat?
- inflammation of the gums and mouth
- stomatitis, a condition with painful swelling and sores inside the mouth
- an ulcer of the duodenum
- stress ulcer prevention
- inflammation of mucous membranes due to sclerotherapy
- ulcers of the esophagus caused by sclerotherapy
What conditions does Carafate treat?
- Citation: Bramhall SR, Mourad MM. Is there still a role for sucralfate in the treatment of gastritis? World J Meta-Anal 2020; 8 (1): 1-3
- URL: https://www.wjgnet.com/2308-3840/full/v8/i1/1.htm
- DOI: https://dx.doi.org/10.13105/wjma.v8.i1.1
How effective is Carafate for gastritis?
What is Carafate 1GM tablets used for?
This medication is used to treat and prevent ulcers in the intestines. Sucralfate forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal more quickly.
What does Carafate do for your stomach?
Carafate is an anti-ulcer medication. Carafate is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by sticking to ulcer sites and protecting them from acids, enzymes, and bile salts. Carafate is used to treat an active duodenal ulcer.
What symptoms does Carafate help?
What Conditions does CARAFATE Treat?reflux esophagitis, or inflammation of the esophagus from backflow of stomach acid.gastroesophageal reflux disease.a stomach ulcer.medication treatment for healing stomach ulcer.an ulcer of the duodenum.medication treatment for healing ulcer of the duodenum.stress ulcer prevention.More items...
Does Carafate work immediately?
How long does it take for sucralfate (Carafate) take to work? The medication will start to work and create a lining as soon as it reaches your GI tract (usually within an hour). Unlike other ulcer medications, like TUMS or omeprazole (Prilosec), you might not be able to feel the effects of the medication right away.
Is Carafate good for acid reflux?
Carafate (sucralfate) and omeprazole are used to treat ulcers and gastroesophageal reflux disease (GERD).
Does Carafate make you sleepy?
itching, rash; dizziness, drowsiness; sleep problems (insomnia);
Does Carafate heal the esophagus?
It is concluded that treatment with sucralfate improves the symptomatology and severity of reflux esophagitis. The results obtained with sucralfate appear comparable to those with cimetidine. Sucralfate may therefore be considered as a valid alternative to H2-receptor antagonist therapy in treating reflux esophagitis.
How long does Carafate coat the stomach?
The sucralfate-albumin film provides a barrier to diffusion of hydrogen ions. In human subjects, Sucralfate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%. One dose lasts approximately 6 hours. It may take up to eight weeks before an ulcer is fully healed.
Does Carafate help gastritis?
Sucralfate is the primary agent for prophylaxis of stress gastritis. It has long been used as a means of decreasing the incidence of gastritis. This drug is readily available, easy to administer, and inexpensive.
Is sucralfate like Pepto Bismol?
Pepto-Bismol (bismuth subsalicylate) Carafate (sucralfate) has few side-effects, but is more expensive than other medicines used to treat ulcers. Relieves heartburn, upset stomach, and diarrhea.
Can I drink coffee with Carafate?
Do not take antacids (e.g. Mylanta) 30 minutes before or after taking sucralfate. Avoid foods and drinks that may upset your stomach such as alcohol, citrus fruits and juices, drinks containing caffeine, tomatoes, or spicy food - as these may delay healing of the stomach/duodenal ulcers.
Does Carafate help stomach pain?
Sucralfate administration was accompanied by the disappearance of heartburn, epigastric pain, epigastric distress, or epigastric burning in 42 of 59 occurrences, and by statistically significant reductions in bloating. There was a trend toward significance in decreased nocturnal abdominal pain and in belching.
Before Taking This Medicine
You should not use Carafate if you are allergic to sucralfate.To make sure Carafate is safe for you, tell your doctor if you have: 1. diabetes; 2....
How Should I Take Carafate?
Take Carafate exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smalle...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember, but avoid taking any other medications within 2 hours before or after you take Carafate. Skip the mis...
What Other Drugs Will Affect Carafate?
Carafate can make it harder for your body to absorb other medications you take by mouth. Avoid taking any other medications within 2 hours before o...
What are the side effects of carafate?
The most common side effects of Carafate include: constipation, diarrhea, nausea, vomiting, upset stomach,
How to report carafate side effects?
These are not all the possible side effects of Carafate. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How is sucralfate absorbed?
Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. The following observations also appear pertinent: 1 Studies in human subjects and with animal models of ulcer disease have shown that sucralfate forms an ulcer-adherent complex with proteinaceous exudate at the ulcer site. 2 In vitro, a sucralfate- albumin film provides a barrier to diffusion of hydrogen ions. 3 In human subjects, sucralfate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%.
Does sucralfate help with duodenal ulcers?
While short-term treatment with sucralfate can result in complete healing of the ulcer, a successful course of treatment with sucralfate should not be expected to alter the post healing frequency or severity of duodenal ulceration. Episodes of hyperglycemia have been reported in diabetic patients.
Is carafate safe for children?
Carafate belongs to a class of drugs called Gastrointestinal Agents, Other. It is not known if Carafate is safe and effective in children.
Does sucralfate reduce absorption?
Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin , fluoroquinolone antibiotics, ketoconazole, l- thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline.
Can sucralfate be overdosed?
Due to limited experience in humans with overdosage of sucralfate, no specific treatment recommendations can be given. Acute oral studies in animals, however, using doses up to 12 g/kg body weight, could not find a lethal dose. Sucralfate is only minimally absorbed from the gastrointestinal tract. Risks associated with acute overdosage should, therefore, be minimal. In rare reports describing sucralfate overdose, most patients remained asymptomatic. Those few reports where adverse events were described included symptoms of dyspepsia, abdominal pain, nausea, and vomiting.
How long does sucralfate last?
Inform your doctor if your condition persists or worsens after you have been taking sucralfate for 4 weeks. Side Effects. Constipation, dry mouth, upset stomach, gas, and nausea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
What is sucralfate used for?
This medication is used to treat and prevent ulcers in the intestines. Sucralfate forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal more quickly.
How to report sucralfate side effects in Canada?
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking sucralfate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Can elderly people take sucralfate?
This medication contains aluminum, which is normally removed by your kidneys. Therefore, elderly people may be at greater risk for developing high aluminum levels while using this drug with other products that contain aluminum (e.g., antacids). If you are pregnant, tell your doctor before using sucralfate.
Is First Databank copyrighted?
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
Can you take sucralfate while pregnant?
If you are pregnant, tell your doctor before using sucralfate. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects.
How to take sucralfate?
Take sucralfate on an empty stomach. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). If you are diabetic, check your blood sugar regularly. Your doctor may adjust your dose based on your blood sugar levels.
How long does sucralfate last?
Sucralfate is used short-term (up to 8 weeks) to treat an active duodenal ulcer. Sucralfate works mainly in the lining of the stomach and is not highly absorbed into the body. sucralfate adheres to ulcer sites and protects them from acids, enzymes, and bile salts. Sucralfate can heal an active ulcer, but it will not prevent future ulcers ...
How long before sucralfate can you take an antacid?
Some antacids can make it harder for sucralfate to work in your stomach. Avoid taking an antacid within 30 minutes before or after taking sucralfate.
How long does antacid last?
1 g orally 4 times a day#N#-Duration of therapy: 4 to 8 weeks#N#Comments:#N#-Each dose should be taken on an empty stomach.#N#-For most patients, treatment should continue for 4 to 8 weeks; however, treatment may be stopped early if healing is demonstrated on x-ray/endoscopic tests.#N#- Antacids may be given, but use should be separated by at least 30 minutes .#N#Use: Short-term treatment of active duodenal ulcers
Does sucralfate help with ulcers?
sucralfate adheres to ulcer sites and protects them from acids, enzymes, and bile salts. Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring.
Where is sucralfate absorbed?
The small amounts of the ... Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. Although the mechanism of sucralfate’s ability to accelerate healing of duodenal ulcers remains to be fully defined, ...
How long does it take for sucralfate to heal?
While healing with sucralfate may occur during the first week or two, treatment should be ... Short-term treatment (up to 8 weeks) of active duodenal ulcer.
How long does it take for antacids to heal after sucralfate?
Antacids may be prescribed as needed for relief of pain but should not be taken within one-half hour before or after sucralfate. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.
Does sucralfate increase aluminum?
When sucralfate is administered orally, small amounts of aluminum are absorbed from the gastrointestinal tract. Concomitant use of sucralfate with other products that contain aluminum, such as aluminum-containing antacids, may increase the total body burden of aluminum. Patients with normal renal function receiving the recommended doses ...
Is carafate a contraindication?
Carafate is contraindicated in patients with known hypersensitivity reactions to the active substance or to any of the excipients. Carafate is contraindicated in patients with known hypersensitivity reactions to the active substance or to any of the excipients.
Does sucralfate form an ulcer-adherent complex?
1. Studies in human subjects and with animal models of ulcer disease have shown that sucralfate forms an ulcer-adherent complex with proteinaceous exudate at the ulcer site. 2. In v i tro , a sucralfate-albumin film provides a barrier to diffusion of hydrogen ions.
Can sucralfate be given to humans?
Due to limited experience in humans with overdosage of sucralfate, no specific treatment recommendations can be given. Acute oral toxicity studies in animals, however, using doses up to 12 g/kg body weight, could not find a lethal dose. Sucralfate is only minimally absorbed from the gastrointestinal tract.
Description
This medication is used to treat and prevent ulcers in the intestines.
May Treat: Duodenal ulcer · Gastroesophageal reflux disease · Maintenance of healing duodenal ulcer
Drug Class: Peptic Ulcer - Gastric Lumen Adherent Cytoprotectives
Availability: Prescription Required
Pregnancy: Consult your doctor
Lactation: Consult a doctor before using
May Treat: Duodenal ulcer · Gastroesophageal reflux disease · Maintenance of healing duodenal ulcer
Drug Class: Peptic Ulcer - Gastric Lumen Adherent Cytoprotectives
Availability: Prescription Required
Pregnancy: Consult your doctor
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: SANOFI-AVENTIS
- Take on an empty stomach
- Take doses regularly, even when feeling well
- Do not stop medicine without calling doctor
- Take on an empty stomach
- Take doses regularly, even when feeling well
- Do not stop medicine without calling doctor
- Do not take antacids within 1/2 hour
- Call MD or RPh re. timing of taking with other meds
- Review all drugs you are taking with your doctor
- May take 8 weeks for full benefit of therapy
- For suspension, oral products : Shake well & measure with dosing spoon/cup/syringe.
- For tablet products : Take at the same time every day.
Carafate Tablets - Clinical Pharmacology
Clinical Trials
Indications and Usage
Contraindications
Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied