What is a bacteriostatic water?
Bacteriostatic water is both a bacteriostatic agent and a key ingredient in laboratories, hospitals, and research centers around the world. Bacteriostatic agents have been used for as long as modern medicine has been practiced. These agents are used to prevent the growth of bacteria in different formulas, canisters, containers, and utensils.
How should I store unused bacteriostatic water?
Keep your unused bacteriostatic water in the container it arrives in. Store the container in a dark place with a residual, resting room temperature that doesn’t exceed 80 degrees Fahrenheit and doesn’t drop below 60 degrees Fahrenheit.
What is the USP for bacteriostatic water for injection?
Bacteriostatic Water for Injection, USP must be made approximately isotonic prior to use. Benzyl alcohol, a preservative in Bacteriostatic Water for Injection, USP has been associated with toxicity in neonates. Data are unavailable on the toxicity of other preservatives in this age group.
How long do bacteriostatic water vials last?
Whether your bacteriostatic water vials come with rubber stoppers or flip top lids, the storage rules should largely remain the same. If your vial has been opened, you should make sure to use the water within a month.
How do you store bacteriostatic water?
Bacteriostatic Water for Injection, USP is supplied in a multiple-dose 30 mL plastic fliptop vial (List No. 3977). Store at 20 to 25°C (68 to 77°F).
Do you have to refrigerate bacteriostatic water?
Mix thoroughly with desired drug and use promptly after mixing. After the first time the water is used, label the vial with date and time to ensure preservative integrity (25-28 days once opened). Store at 20 to 25 Celsius (68 to 77 degrees Fahrenheit).
How long does bacteriostatic water last once opened?
28 daysHow long does Bacteriostatic water last after it has been opened? Hospira recommends that once a vial of Bacteriostatic Sterile water is open the preservatives will prolong its life for up to 28 days. After 28 days the vial needs to be discarded.
Does sterile water for injection need to be refrigerated?
After initial entry, maintain contents at room temperature (25°C/77°F) and dispense within 4 hours. Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C/77°F).
How long is sterile water good for?
A container label that states “single dose container” on any bottle of sterile irrigation fluids indicates that once opened, any unused fluid must be immediately discarded.
Can you use bacteriostatic water after the expiration date?
When the vial is opened the water should be used within 28 days. After this time it is best to discard it. It should be stored in a dark place at temperatures between 60 to 77 degrees Fahrenheit. Bacteriostatic water is safe in most applications.
Can you store bacteriostatic saline?
Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.]
Why is there a shortage of bacteriostatic water?
Reason for the Shortage Pfizer has bacteriostatic water for injection on shortage due to increased demand.
Can I buy bacteriostatic water at a pharmacy?
If you are needing bacteriostatic water for a medication today, you can shop around at various local pharmaceutical retailers, such as Walgreens, CVS, or Walmart. Their pharmacies should have bacteriostatic water in stock and have trusted suppliers for this product.
Is bacteriostatic water the same as sterile water?
Answer: Bacteriostatic water differs from sterile water by the addition of benzyl alcohol as a preservative with a final concentration of 0.9%. Benzyl alcohol can be a topical irritant but in the concentration of 0.9% does not typically cause irritation and may provide some anesthetic effects.
Why water for injection should be stored at 2 C or 80 C?
According to the USP, a temperature of 80 °C during sanitisation serves to achieve the necessary germicidal temperature even at colder points in the (ring pipe) system.
Can ambisome be refrigerated?
Prior to reconstitution Amphotericin B for Injection USP should be stored under refrigeration, 2° to 8°C (36°to 46°F), protected against exposure to light.
Can I use sterile water instead of bacteriostatic water?
It depends on the application. Sterile water is used for irrigating wounds and injecting medications, but it cannot be used more than once. Bacteri...
Is it safe to inject bacteriostatic water?
It is only safe to inject bacteriostatic water when it is diluted with the appropriate medication and aseptic techniques are closely followed. Inje...
What is the difference between bacteriostatic and sterile water?
Sterile water has been cleared of any contaminants, but it does not contain any antibacterial agents. Therefore, it can only be used once. Bacterio...
What is the difference between sterile water and bacteriostatic water?
The difference between bacteriostatic water and sterile water is that other sterile waters for injection do not contain a bacteriostatic agent. As such, they are single-dose vials and should be discarded after a single use.
How long does a vial of sterile water last?
Hospira, the world’s leading manufacturer and supplier of bacteriostatic and sterile water, advises that once a vial of bacteriostatic water is open, the preservatives will prolong its life for up to 28 days.
Bacteriostatic Definition
What does bacteriostatic mean? Bacteriostatic is a term used to describe any agent or substance that has the ability to prevent bacterial growth. Bacteriostatic solutions differ from bactericidal solutions in that bactericidal agents have the ability to kill bacteria.
Bacteriostatic Water
What is bacteriostatic water? Bacteriostatic water is a sterile solution that contains 0.9% benzyl alcohol. Benzyl alcohol is an aromatic organic molecule with a six-membered ring and one hydroxymethyl (CH 2 -OH) attachment. The alcohol is an added preservative that contributes to the solution's bacteriostatic nature.
Bacteriostatic Water for Injection
Primarily, healthcare professionals use bacteriostatic water for injection purposes. Most drugs must be diluted to their proper concentrations before being introduced to the human body. This is to ensure that the drug is not administered at levels that may be toxic to the patient.
Can bacteriostatic water be used for pregnancy?
Pregnancy: Animal reproduction studies have not been conducted with Bacteriostatic Water for Injection. It is also not known whether Bacteriostatic Water for Injection containing additives can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.
Can you use Bacteriostatic Water for intravenous injection?
Do not use Bacteriostatic Water for Injection, USP for intravenous injection unless the osmolar concentration of additives results in an approximate isotonic admixture. Consult the manufacturer's instructions for choice of vehicle, appropriate dilution or volume for dissolving the drugs to be injected, including the route and rate of injection.
What is bacteriostatic water?
Bacteriostatic Water And Purity. Bacteriostatic water is a sterile form of water that has been brought to a pH between 4.5 to 7.0. It also is prepared with a bacteriostat, a compound used to prevent any bacterial growth. This bacteriostat is usually 0.9% benzyl alcohol. It is only used for injections such as intravenous, ...
How long can you use Bacteriostatic Water?
Bacteriostatic water can be used multiple times for up to 28 days before the suggested disposal. This can come into play when preparing for traveling, budgeting monthly expenses and storage. Medications that required diluting with water usually indicate on the bottle which water is preferred for use.
What is the difference between sterile water and bacteriostatic water?
Sterile water is labeled for both injections and irrigations whereas bacteriostatic water is only labeled for injections. Touched on earlier, another key difference is multiple uses. The absence of a bacteriostat in sterile water only allows for a one time use. Bacteriostatic water can be used multiple times for up to 28 days before ...
What are sterile solutions?
Two sterile solutions that are commonly used are bacteriostatic water and sterile water.
Is sterile water distilled?
As mentioned previously, sterile water only. has distilled water and nothing else. Bacteriostatic water is water with benzyl alcohol. Immediately you can gauge which is appropriate based on allergies. If you have an allergy to benzyl alcohol, discontinue or avoid bacteriostatic water and opt for sterile water.
Can sterile water cause fever?
Using in such a matter can cause hemolysis or destruction of red blood cells. They both are nonpyrogenic meaning they won’t cause fever.
Is Bacteriostatic Water contraindicated?
A major difference between the two is the patient population. Bacteriostatic water is contraindicated, or forbidden, from being used in neonates, newborns in the first 28 days of their life. Another key difference is availability.
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Clinical Pharmacology
Indications and Usage
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Dosage and Administration
How Is Bacteriostatic Water For Injection Supplied
- Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Distributed by Hospira, Inc., Lake Forest, IL 60045 USA LAB-0977-2.0 Revised: 08/2019