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where is lamina found

by Darius Larkin I Published 3 years ago Updated 3 years ago

The lamina presents various parts, including:

  • Veins: The vascular bundle which is found not far from the plant’s surface. The veins also carry food and water alike. ...
  • Lobes: The rounded portion of the leaf margin. ...
  • Margins: The margins trace the edges of the leaf to mark the boundary.
  • Leaf apex: This refers to the very tip of the leaf which is right opposite the petiole.

The lamina is the part of the vertebra that connects the spinous process and the transverse process. There are two laminae, located on either side of the spinous process. The lamina is often the site of back surgery when you need to relieve the symptoms caused by pressure on the spinal nerve roots.Jun 6, 2022

Full Answer

Where are the stomata located?

The majority of stomata are located on the underside of plant leaves reducing their exposure to heat and air current. In aquatic plants, stomata are located on the upper surface of the leaves. Subsequently, question is, are stomata found on both sides of a leaf? Stomata are found on stamens and gynoecia.

Where is the reticular formation located in?

Traditionally the reticular nuclei are divided into three columns:

  • In the median column – the raphe nuclei
  • In the medial column – gigantocellular nuclei (because of larger size of the cells)
  • In the lateral column – parvocellular nuclei (because of smaller size of the cells)

What happens during a laminectomy?

  • laminectomy – where a section of bone is removed from 1 of your vertebrae (spinal bones) to relieve pressure on the affected nerve
  • discectomy – where a section of a damaged disc is removed to relieve pressure on a nerve
  • spinal fusion – where 2 or more vertebrae are joined together with a section of bone to stabilise and strengthen the spine

Where is lamina propria found?

Quiz

  1. Which of the following is NOT an element of the mucous membrane? A. Lamina propria B. ...
  2. Which of the following best describes the function of the lamina propria? A. ...
  3. The mucous membranes in the throat are relatively smooth, while the mucous membranes in the intestines are rough. ...

Where is a lamina located?

The lamina is the flattened or arched part of the vertebral arch, forming the roof of the spinal canal; the posterior part of the spinal ring that covers the spinal cord or nerves.

Where is the lamina densa located?

The lamina densa is a component of the basement membrane zone between the epidermis and dermis of the skin, and is an electron-dense zone between the lamina lucida and dermis, synthesized by the basal cells of the epidermis, and composed of (1) type IV collagen, (2) anchoring fibrils made of type VII collagen, and (3) ...

What is mean lamina in biology?

noun, plural lam·i·nae [lam-uh-nee], lam·i·nas. a thin plate, scale, or layer. a layer or coat lying over another, as the plates of minerals or bones. Botany. the blade or expanded portion of a leaf.

Which layer contains the lamina propria?

Which layer contains the lamina propria? The mucosa is the innermost layer of the GI tract. It consists of epithelium, lamina propria, and muscularis mucosa.

What is lamina densa in the kidney?

The Urinary System1 The glomerular basement membrane has a thick, dense central layer, the lamina densa, which is covered by thinner, more electron-lucent inner and outer layers, the lamina rara interna and lamina rara externa, respectively (see Fig. 11-6).

Where is basement membrane found?

The basement membrane lies between the epidermis, or outer layer of skin, and the dermis, the middle layer of skin, keeping them tightly connected. But basement membranes aren't just found in the skin.

Where is lamina in leaf?

leaf structure …a broad expanded blade (the lamina), attached to the plant stem by a stalklike petiole. In angiosperms leaves commonly have a pair of structures known as stipules, which are located on each side of the leaf base and may resemble scales, spines, glands, or leaflike structures.

What is lamina in plant leaf?

The lamina is the expanded, flat component of the leaf which contains the chloroplasts. The sheath is a structure, typically at the base that fully or partially clasps the stem above the node, where the latter is attached.

What is a function of lamina?

The leaf lamina is the blade-like structure of a leaf. It is typically green and is responsible for photosynthesis in the plant. The lamina is also responsible for the movement of water and nutrients between the plant and the environment.

Is the lamina propria part of the submucosa?

The mucosa consists of the epithelium itself and also the supporting loose connective tissue, called lamina propria, immediately beneath the epithelium. Deeper connective tissue which supports the mucosa is called the submucosa....Basic Tissues.Epithelial Tissue / GlandsConnective TissueNervous TissueMuscle Tissue

In which layer is the lamina propria found quizlet?

The mucosa consists of an inner epithelium, a loose connective tissue called lamina propria, and a thin layer of smooth muscle called muscularis mucosae.

Where is the lamina propria in the stomach?

The lamina propria is the layer of connective tissue located just deep to the surface epithelium. It contains blood and lymphatic vessels, lymphoid tissue and surrounds the gastric glands.

1. What is the lamina of a leaf?

The lamina of the leaf is a flat and thin structure of the leaf that contains the chloroplast and the stomata. It is made up of the mesophyll tissu...

2. What is the difference between leaf lamina and leaf blade?

Plant leaf lamina is the flat region of the leaf containing the chloroplasts, veins and the stomata. On the other hand, the leaf blade, in botanica...

3. What is leaf blade and leaf apex ?

Biologists or Botanists have categorised or named various parts of the Leaf for its easy recognition and understanding the various functions perfor...

4. How does the stomata of leaves function ?

Stomata are the small openings present on both the surface of any Leaf. The basic function of the stomata is to carry out the respiration and intak...

5. Is it sufficient for students of Class 11 Science stream to learn only about the exterior parts o...

In Class 11, science stream of both CBSE and ICSE boards, the subject of Biology covers all the external parts of a Leaf and the internal parts as...

6. Where can I find the study materials to learn about the internal structures of the Leaf and their...

Leaves are the very crucial organs for the survival of any tree or Plant. It helps trees to get food for their growth and nutrition. All these proc...

7. What is the cost of all the study materials provided by Vedantu ?

Vedantu website is a platform for online studies helping out students for their exam preparation across India. Any student can get enrolled in Veda...

Where is the lamina propria located?

This can be seen in the image below, of a small intestine. The lamina propria is labeled on the bottom left. Mucous membranes line various organs and body cavities which have access to the outside, such as the lungs, intestines, and stomach. There are also mucous membranes in the nose, mouth, and on the tongue.

What is the lamina propria?

Lamina Propria Definition. The lamina propria is one of three layers which make up the mucosa, or mucous membrane. The lamina propria is a large layer of connective tissue which separates the innermost layer of epithelial cells from a layer of smooth muscle tissue called the muscularis mucosa. This can be seen in the image below, ...

Why is the lamina propria important?

Besides these obvious physical functions, the lamina propria has an important immune function. Because the layer is created by a complex arrangement of structural molecules, there is very little room for bacteria, viruses, and general debris to make their way into the cells or bloodstream.

What is the function of the lamina propria?

The lamina propria also serves as an important physical barrier which stops unwanted materials and organisms from gaining access to the body.

What are the molecules that make up the lamina propria?

These molecules include collagen, a standard animal structural protein, as well as laminins, perlecan, and entactin . These molecules form complex sheets which can be layered to form the thick lamina propria. Each organ has a specific purpose, and therefore a different configuration of the mucosa which covers the organ.

Which membranes are smooth?

3. The mucous membranes in the throat are relatively smooth, while the mucous membranes in the intestines are rough. The lamina propria in the intestines has many folds, which create the rough surface.

Where are the laminae located?

Laminae I-VI comprise the entirety of the dorsal horn, where, alternatively, the spinal cord nuclei, marginal zone (MZ), substantia gelatinosa (SG), and nucleus proprius (NP) are located. Recall that sensory nerve fibers, transmitting information into the CNS and up to the brain, synapse onto interneurons in the dorsal gray horn.

What is the function of the lamina I?

Lamina I makes up the tip of the dorsal horn and is responsible for receiving noxious or thermal stimuli (noxious refers to stimuli that indicate an event that is either certainly or potentially damaging to tissues/organs. These stimuli can be mechanical, chemical, or thermal).

What are the laminae of the spinal cord?

Laminae VIII-IX. Laminae X. References. Image source. The cellular laminae, also known as Rexed laminae, are the nine layers of gray matter that make up the spinal cord. These layers are organized in two main ways: by nuclear regions (we will discuss this briefly only as a way to identify laminar regions) and by the laminae themselves.

Which lamina is the middle region of the vertebral column?

Lamina VII. Lamina VII, along with Lamina IX, form the middle region between the dorsal and ventral roots, medial to the position of the lateral gray horns. This lamina is one example of a layer that changes configuration based on the level of the vertebral column observed.

Which lamina relays sensory information to the brain?

Lamina V relays sensory information – particularly nociceptive (meaning potentially painful) sensory signals – to the brain via the lateral spinothalamic tracts. This lamina also receives descending information from the brain via the corticospinal and rubrospinal tracts.

Which lamina controls the sensations of proprioception?

Lamina III controls the sensations of proprioception (awareness of the positioning of body parts) and light touch (note that different pressures associated with touch involve different sensory receptors and nerve pathways). The cells of this lamina are connected with Laminae IV, V, and VI, and in part, corresponds to the spinal cord nucleus, ...

What is the role of Lamina IV?

Lamina IV is involved in the reception and distribution of non-noxious (stimuli that do not pose or warn of a threat) sensory information and processing. Lamina IV maintains a direct connection to Lamina II, despite their non-continuous positions.

Why is the lamina propria important?

Because the epithelium is often under external stress and is somewhat delicate, the lamina propria hosts many immune cells. In the intestinal tract the immune system must have tolerance to the normal intestinal flora, yet respond to pathogenic microorganisms. Imbalance of this causes inflammation diseases such as inflammatory bowel disease. The lamina propria’s richness in macrophages and lymphoid cells makes it a key place for immune responses to occur. It forms part of the barrier that protects internal tissues from external pathogenic microorganisms, especially from the gastrointestinal tract.

What is the role of the lamina propria macrophages in cancer?

The lamina propria macrophages when under much stress release pro-inflammatory signals that may lead to increased probability of developing cancer. An example of this is the over activation of the IL-6 / STAT3 pathway, which has been linked to colitis-associated cancer.

What is the thin layer of connective tissue?

Thin connective layer forming part of the mucous membranes. Lamina propria. The lamina propria , a thin layer of connective tissue, is part of the mucosa. Here is an example of the mucosa of the mouth. Details.

What is the name of the thin layer of connective tissue that forms part of the moist linings of the

Mucosa. Identifiers. Latin. lamina propria mucosæ. FMA. 62517. Anatomical terminology. The lamina propria is a thin layer of connective tissue that forms part of the moist linings known as mucous membranes or mucosa, which line various tubes in the body, such as the respiratory tract, the gastrointestinal tract, and the urogenital tract.

Where do myofibroblasts live?

It has been suggested that myofibroblasts also reside in the lamina propria of several organs. These cells have characteristics of both smooth muscle and fibroblasts. The lamina propria may also be rich in vascular networks, lymphatic vessels, elastic fibers, and smooth muscle fascicles from the muscularis mucosae.

Where do lymphatics drain?

Lymphatics penetrate the mucosa and lie below the basement membran e of the epithelium, from there they drain the lamina propria. The fast rate of cell death and regeneration of the epithelium leaves behind many apoptotic cell bodies.

Which organs require expansion?

The connective tissue and architecture of the lamina propria is very compressible and elastic, this can be seen in organs that require expansion such as the bladder. The collagen in the lamina propria of elastic organs has been shown to play a major role in mechanical function.

What is the base of a lamina called?

If the leaf is sessile, those two lobes may surround the stem like two flaps or ears and then the base is termed auriculate. ADVERTISEMENTS: This is seen in Calotropis procera.

What is the apex of a lamina?

The apex of the lamina may be : (1) Acute —when pointed and narrow as in mango. (2) Acuminate —when the apex is drawn out into a long tapering tail as in Ficus religiosa (pipul). (3) Obtuse —when the apex is broad angled and blunt as in banyan.

Which tissue system reaches the base of the lamina through the petiole?

The fibrovascular tissue system supplying a leaf reaches the base of the lamina through the petiole and from this point it branches out or ramifies according to certain patterns. The ramifications are called veins and their arrangement is known as vena­tion.

Which leaf is actually the midrib?

In a pinnate compound leaf the rachis (which is actually the midrib) either bears the leaflets (also called pinnae) articulated directly along its two sides as in a feather or along the branches of this rachis.

What does it mean when the basal lobes fuse together?

If the basal lobes fuse together after completely clasping the stem it seems that the stem has perforated the leaf. This is called perfoliate and is found in Aloe perfoliata, Pladera perfoliata, Bupleurum, etc.

Where is venation on a plant?

Venation is very clear on the lower surface of thin leaves. Venation follows certain basic patterns. In lower plants like the Pteridophytes, the branching of the veins is dichotomous. The Angiosperm leaf shows two principal types of venation.

Which leaf has reticulate veins?

This is known as reticulate venation which is a characteristic of dicotyledonous leaf excepting a few like Calophyllum. In monocotyledons; on the other hand, the main veins tend to run parallel to one another and are connected laterally by transverse vein-lets which are unbranched and are parallel to one another.

What are lamins in the nucleus?

Due to their properties as a type of IF protein, lamins provide support for maintaining the shape of the nucleus. They also play an indirect role in anchoring the nucleus to the endoplasmic reticulum, forming a continuous unit within the cell. This is accomplished by lamin and lamin-interacting proteins (SUN1/SUN2) connecting with proteins on the outer nuclear membrane. These proteins in turn interact with cytoskeletal elements of the endoplasmic reticulum, forming a strong complex that can withstand mechanical stress. Nuclei that lack lamins or have mutated versions have a deformed shape and do not function properly.

What are nuclear lamins?

Lamins, also known as nuclear lamins are fibrous proteins in type V intermediate filaments, providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with inner nuclear membrane proteins to form the nuclear lamina on the interior of the nuclear envelope. Lamins have elastic and mechanosensitive ...

How are lamins A and C created?

Two isoforms, lamins A and C, can be created from this gene via alternative splicing. This creates a high amount of homology between the isoforms. Unlike lamin C, Lamin A is generated in a precursor form called prelamin A. Prelamin A and lamin C differ in structure only at the carboxyl-terminus.

What family do lamins belong to?

It wasn't until 1986 that an analysis of lamin cDNA clones across a variety of species supported that lamins belong to the intermediate filament (IF) protein family. Further investigations found evidence that supports that all IF proteins arose from a common lamin-like ancestor.

How do dimers form lamin filaments?

The dimers arrange themselves in a head-to-tail manner, allowing for the formation of a protofilament. As these protofilaments aggregate, they form lamin filaments. Lamins of higher level organisms, such as vertebrates, continue to assemble into paracrystalline arrays.

Why is prelamin A not processed?

Because prelamin A cannot be properly processed during posttranslational modifications, it retains its lipid modification (farnesylation) and remains in the inner nuclear membrane. This disrupts the mechanical stability of the nucleus, resulting in a higher rate of cell death and therefore a higher rate of aging.

What are the three units of lamins?

The structure of lamins is composed of three units that are common among intermediate filaments: a central α-helical rod domain containing heptad repeats surrounded by globular N and C-terminal domains. The N-terminal is shorter and located at the top (head) while the C-terminal is longer and located at the end (tail). Lamins have a unique structure of the heptad repeats that is continuous in nature and contains an additional six heptads. While the head domain of lamins is fairly consistent, the composition of the tail domain varies based on the type of lamin. However, all C-terminal domains contain a nuclear localization sequence (NLS). Similar to other IF proteins, lamins self-assemble into more complex structures. The basic unit of these structures is a coiled-coil dimer. The dimers arrange themselves in a head-to-tail manner, allowing for the formation of a protofilament. As these protofilaments aggregate, they form lamin filaments. Lamins of higher level organisms, such as vertebrates, continue to assemble into paracrystalline arrays. These complex structures allow nuclear lamins to perform their specialized functions in maintaining the shape of the nucleus as well as roles during mitosis and apoptosis.

What is the basal lamina?

Anatomical terms of microanatomy. The basal lamina is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits . It is often incorrectly referred to as the basement membrane, though it does constitute a portion of the basement membrane.

Which layer of the lamina is composed of collagen?

electron-dense layer composed of type IV collagen. lamina reticularis. no. yes. The three above layers of the basal lamina typically sit on top of the reticular lamina, which is synthesized by cells from the underlying connective tissue and contains fibronectin.

What is the function of the basal lamina?

The basal lamina is made and maintained by the cells that sit on it. It acts as a point of attachment for cells. However, it can also have other function such as a permeability barrier in the glomerulus (urine production). Some of the matrix molecules (of the basal lamina) mediate synaptic adhesion in neuromuscular synapses (citation: [edited by] Bradley G. Klein. Cunningham's Textbook of Veterinary Physiology. St. Louis, Mo. :Elsevier/Saunders, 2013. Print.-page61).

What is the lamina densa?

The lamina densa was formerly called the “basal lamina”. The terms “basal lamina” and “basement membrane” were often used interchangeably, until it was realised that all three layers seen with the electron microscope constituted the single layer seen with the light microscope.

What is the glomerular basement membrane?

The glomerular basement membrane is a special case, consisting of a fusion of the podocyte and endothelial basal laminas, and lacking a lamina reticularis.

How thick is the basal lamina?

The basal lamina is visible only with the electron microscope, where it appears as an electron-dense layer that is 20–100 nm thick (with some exceptions that are thicker, such as basal lamina in lung alveoli and renal glomeruli).

Is the lamina lucida the same as the lamina densa?

Some theorize that the lamina lucida is an artifact created when preparing the tissue, and that the lamina lucida is therefore equal to the lamina densa in vivo. The term "basal lamina" is usually used with electron microscopy, while the term "basement membrane" is usually used with light microscopy . Examples of basement membranes include:

What is the lamina of the vertebra?

vertebral lamina(lamina of vertebral arch) either of the pair of broad plates of bone flaring out from the pedicles of the vertebral archesand fusing together at the midline to complete the dorsal part of the arch and provide a base for the spinous processof the vertebra.

What is the lamina fus?

lamina fus´cathe pigmentary layer of the sclera. lamina lu´cidaan electron-dense layer of the basal laminalying between the lamina densaand the adjoining cell layer; in the pulmonary alveolus and renal glomerulus it is divided into the internal and external laminae rarae. lamina pro´pria.

What is the lamina rara externais?

1.in the renal glomerulus and pulmonary alveolus, one of the layers of lamina lucidasurrounding the lamina densa; the lamina rara externais on the epithelial side and the lamina rara internais on the endothelial side. 2.a term sometimes used as a synonym for lamina lucida.

What is the lamina choroidocapilla?

lamina choroidocapilla´risthe inner layer of the choroid, composed of a single-layered network of small capillaries. lamina cribro´sa. 1.fascia cribrosa. 2. (of ethmoid bone) the horizontal plate of ethmoid bone forming the roof of the nasal cavity, and perforated by many foramina for passage of olfactory nerves. 3.

What is the term for a thin, flat plateor stratumof a composite structure?

1.a thin, flat plateor stratumof a composite structure; called also layer. 2.vertebral lamina. basal lamina(lamina basa´lis) the layer of the basement membranelying next to the basal surface of the adjoining cell layer composed of an electron-dense lamina densaand an electron-lucent lamina lucida.

What is the Rexed laminaean architectural scheme?

Rexed's laminaean architectural scheme used to classify the structure of the spinal cord, based on the cytological features of the neurons in different regions of the gray substance. It consists of nine laminae (I–IX) that extend throughout the cord, roughly paralleling the dorsal and ventral columns of the gray substance, ...

What is a thin layer of bone?

A thin layer of bone, membrane, or other tissue. 3. ZoologyA thin scalelike or platelike structure, as one of the thin layers of sensitive vascular tissue in the hoof of a horse. 4. CytologyA thin layer inside the nuclear membrane of cell that is composed of a meshlike network of protein fibers. lam′i·nar, lam′i·naladj.

What is the nuclear lamina?

The nuclear lamina is a dense (~30 to 100 nm thick) fibrillar network inside the nucleus of most cells. It is composed of intermediate filaments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina regulates important cellular events such as DNA replication and cell division.

What are the proteins that are bound to the lamina?

Nuclear envelope proteins that are bound to the lamina include nesprin, emerin, lamina-associated proteins 1 and 2 (LAP1 and LAP2), the lamin B receptor (LBR) and MAN1. Transcription factors that bind to the lamina include the retinoblastoma transcriptional regulator (RB), germ cell-less (GCL), sterol response element binding protein (SREBP1), ...

How is the nuclear lamina formed?

The nuclear lamina is assembled by interactions of two lamin polypeptides in which the α-helical regions are wound around each other to form a two stranded α-helical coiled-coil structure, followed by a head-to-tail association of the multiple dimers. The linearly elongated polymer is extended laterally by a side-by-side association of polymers, resulting in a 2D structure underlying the nuclear envelope. Next to providing mechanical support to the nucleus, the nuclear lamina plays an essential role in chromatin organization, cell cycle regulation, DNA replication, DNA repair, cell differentiation and apoptosis .

What are the proteins that are associated with nuclear lamina?

The nuclear lamin-associated membrane proteins are either integral or peripheral membrane proteins. The most important are lamina associated polypeptides 1 and 2 ( LAP1, LAP2 ), emerin, lamin B-receptor (LBR), otefin and MAN1. Due to their positioning within or their association with the inner membrane, they mediate the attachment ...

What are the different types of lamins in Xenopus laevis?

The major types are LI and LII, which are considered homologs of lamin B 1 and B2. LA are considered homologous to lamin A and LIII as a B-type lamin. A fourth type exists and is germ cell specific.

What are the two components of the nuclear lamina?

The nuclear lamina consists of two components, lamins and nuclear lamin-associated membrane proteins. The lamins are type V intermediate filaments which can be categorized as either A-type (lamin A, C) or B-type (lamin B 1, B 2) according to homology of their DNA sequences, biochemical properties and cellular localization during the cell cycle.

What is the role of nuclear lamina in DNA replication?

Various experiments show that the nuclear lamina plays a part in the elongation phase of DNA replication. It has been suggested that lamins provide a scaffold, essential for the a ssembly of the elongation complexes , or that it provides an initiation point for the assembly of this nuclear scaffold.

Where is the nuclear lamina located?

The nuclear lamina is a structure near the inner nuclear membrane and the peripheral chromatin. It is composed of lamins, which are also present in the nuclear interior, and lamin-associated proteins. The increasing number of proteins that interact with lamins and the compound interactions between these proteins and chromatin-associated proteins ...

What is the nuclear lamina?

The nuclear lamina is a structure near the inner nuclear membrane and the peripheral chromatin. It is composed of lamins, which are also ...

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Lamina Propria Definition

Image
The lamina propria is one of three layers which make up the mucosa, or mucous membrane. The lamina propria is a large layer of connective tissue which separates the innermost layer of epithelial cells from a layer of smooth muscle tissue called the muscularis mucosa. This can be seen in the image below, of a s…
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Lamina Propria Structure

  • The lamina propria varies in chemical composition from animal to animal, and from organ to organ. In general, the lamina propria is a complex mesh of extracellular proteins and structural molecules. These molecules include collagen, a standard animal structural protein, as well as laminins, perlecan, and entactin. These molecules form complex sheets which can be layered to …
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Lamina Propria Function

  • The lamina propria has several functions. The first and most basic is to connect the innermost epithelial cells of organs with the smooth musclelayer which defines a mucous membrane. The molecules within the lamina propria act as a series of chains and hooks, to lock the cells and membrane into place. Then, when the muscular layer of the mucosa contracts, the lamina propri…
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Quiz

  • 1. Which of the following is NOT an element of the mucous membrane? A. Lamina propria B. Blood cells C.Epithelium 2. Which of the following best describes the function of the lamina propria? A. Provides support of the epithelium, and provides a physical barrier against pathogens B. Holds muscles together C.Helps contract muscles and vessels 3. The mucous membranes in …
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Overview

The lamina propria is a thin layer of connective tissue that forms part of the moist linings known as mucous membranes or mucosa, which line various tubes in the body, such as the respiratory tract, the gastrointestinal tract, and the urogenital tract.
The lamina propria is a thin layer of loose (areolar) connective tissue, which lies beneath the epithelium, and together with the epithelium and basement membrane constitutes the mucosa. A…

Structure

The lamina propria is a loose connective tissue, hence it is not as fibrous as the underlying connective tissue of the submucosa. The connective tissue and architecture of the lamina propria is very compressible and elastic, this can be seen in organs that require expansion such as the bladder. The collagen in the lamina propria of elastic organs has been shown to play a major role in mechanical function. In the bladder the collagen composition of its lamina propria allows for …

Function

Because the epithelium is often under external stress and is somewhat delicate, the lamina propria hosts many immune cells. In the intestinal tract the immune system must have tolerance to the normal intestinal flora, yet respond to pathogenic microorganisms. Imbalance of this causes inflammation diseases such as inflammatory bowel disease. The lamina propria’s richness in macrophages and lymphoid cells makes it a key place for immune responses to occ…

Clinical significance

Progression of epithelial cancer often relies on deep and regional lymph node invasion. The lamina propria, being one of the barriers to the submucosa, is an area where epithelial cancer invasion is of significance since lymphatic invasion is an independent predictor of lymph node metastasis, especially in gastric cancer. As soon as the tumors breach the basement membrane and reach the lamina propria, they are exposed to lymphatics which may increase the rate of metastasis and ca…

See also

• Basal lamina (part of which is also known as lamina densa)
• Myofibroblast
• Submucosa

External links

• Anatomy Atlases - Microscopic Anatomy, plate 10.198
• Histology image: 10802loa – Histology Learning System at Boston University - "Digestive System: Alimentary Canal - esophagus "
• Histology image: 03301loa – Histology Learning System at Boston University - "Connective Tissue: lamina propria; loose connective tissue "

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