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what limits the growth of a cell

by Marilyne Brakus Published 3 years ago Updated 2 years ago

Factors limiting the size of cells include:

  • Surface area to volume ratio. (surface area / volume)
  • Nucleo-cytoplasmic ratio.
  • Fragility of cell membrane.
  • Mechanical structures necessary to hold the cell together (and the contents of the cell in place)

Cell growth is limited by rates of protein synthesis, by the folding rates of its slowest proteins, and—for large cells—by the rates of its protein diffusion.

Full Answer

What limits the size of a cell?

What Limits Cell Size? The primary limitation on the size to which a single cell can grow is a mathematical principle called the surface to volume ratio. As the size of a three-dimensional object grows, its volume increases more rapidly than its surface does, which causes metabolic problems for cells.

Why does the nucleus limit the size of a cell?

Because the nucleus must become larger to control a larger cell, the nucleus is also susceptible to the problem of surface to volume ratio. This limits the size of the nucleus, which in turn, limits the size of the entire cell. While the outer membrane of a cell protects the cell well on a microscopic level,...

What are the external limits of cell division?

External Limits. But extracellular factors determine division too. Cells only divide when they receive specific signals from proteins called mitogens, thus the presence of mitogens can limit cell division. Mitogens are needed for cell division in healthy cells and are released depending on what cells the body needs.

What is the maximum number of times a cell can divide?

Internal Limits. All cells in the body have this internal control and most cells only divide between 50-70 times before they stop or die. However, adult stem cells, which are special cells that can make many other types of cells, can divide much longer, and embryonic stem cells can divide nearly indefinitely.

What limits cell size and why?

Cell size is limited by a cell's surface area to volume ratio. A smaller cell is more effective and transporting materials, including waste products, than a larger cell. Cells come in many different shapes.

What limits cell growth and division?

External Limits Cells only divide when they receive specific signals from proteins called mitogens, thus the presence of mitogens can limit cell division. Mitogens are needed for cell division in healthy cells and are released depending on what cells the body needs.

Why are cells limited in growth?

The important point is that the surface area to the volume ratio gets smaller as the cell gets larger. Thus, if the cell grows beyond a certain limit, not enough material will be able to cross the membrane fast enough to accommodate the increased cellular volume.

What limits cell size What problems does growth cause for cells?

1. The larger the cell, the more demands the cell places on its DNA. 2. The cell has trouble moving enough nutrients and wastes across the cell membrane.

What limits the size of a cell quizlet?

The key factor that limits the size of a cell is the ratio of its surface area to its volume.

What controls cell growth?

Cell growth, proliferation and differentiation are controlled largely by selective transcriptional modulation of gene expression in response to extracellular stimuli. Much of this transcriptional control is governed by the action of sequence-specific transcription factors.

What factors affect cell growth?

Factors studied included temperature, level of dissolved oxygen, nutrient depletion, and waste product accumulation. Growing cells at temperatures 3-9 degrees lower than optimum (37 degrees C) increased viability but monoclonal antibody production was lowered.

What single factor limits the size that most cells are able to obtain?

the surface volume ratioThe single factor that limits the size of most of the cell is the surface volume ratio. The size of the cell gets limited by the nucleo-cytoplasmic ratio, which determines the range of control of metabolic ratio and the ratio of surface to volume.

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