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what is the difference between rdw sd and rdw cv

by Cletus Fritsch Published 3 years ago Updated 2 years ago

The RDW-SD is expressed in femtoliters (fL) and is based on the width of RBC volume distribution curve at 20% above baseline (Caporal 2013). The standard lab reference range for RDW-CV is 11-15% and for RDW-SD it is 38-49 fL (Quest). The numbers are not interchangeable.

The two RDW measurements currently in use are the red cell distribution width - coefficient of variation (RDW-CV) and the red cell distribution width - standard deviation (RDW-SD). The RDW-CV is a calculation based on both the width of the distribution curve and the mean cell size.

Full Answer

How do you calculate RDW?

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What does a High RDW SD mean?

What does a high RDW SD mean? High results If your RDW is too high, it could be an indication of a nutrient deficiency, such as a deficiency of iron, folate, or vitamin B-12. These results could also indicate macrocytic anemia, when your body doesn’t produce enough normal red blood cells, and the cells it does produce are larger than normal.

How to calculate RDW?

References

  1. Red Cell Distribution Width in Family Practice Notebook [available online].
  2. Wen Y. High red blood cell distribution width is closely associated with risk of carotid artery atherosclerosis in patients with hypertension. ...
  3. Buttarello M, Plebani M. Automated blood cell counts: state of the art. ...
  4. Balta S, Demirkol S, Aparci M, Yildirim AO, Ozturk C, Celik T. ...

What does a High RDW SD Count indicate?

Results may show:

  • Normal RDW and normal MCV. People with normal results may still have anemia caused by a chronic medical condition or blood loss.
  • Normal RDW and low MCV. This combination may indicate anemia caused by a chronic condition or thalassemia.
  • Normal RDW and high MCV. This can indicate a liver condition or alcohol abuse. ...

Which is better RDW-CV or RDW-SD?

It is important for the entire laboratory staff to understand the RDW-CV and RDW-SD. One advantage of RDW-CV is that it shows better correlation as an indicator of anisocytosis when the MCV is in the low-normal range and when anisocytosis is difficult to detect, such as in mild iron deficiency.

What does a high RDW-CV and RDW-SD mean?

Normally, your red blood cells are all about the same size. A high RDW means that there's a major difference between the size of your smallest and largest red blood cells. This may be a sign of a medical condition. Other names: RDW-SD (standard deviation) test, Erythrocyte Distribution Width.

What does a high RDW-CV mean?

High RDW. A high RDW means that there's variation in the size of your red blood cells beyond what's considered normal. A high RDW may be a sign of anemia or a related condition. Your healthcare provider will need to look at other tests to be sure.

Is RDW the same as RDW-CV?

Certain disorders, however, cause a significantly increased variation in cell size. Higher RDW values indicate greater variation in size. Normal reference range of RDW-CV in human red blood cells is 11.5–15.4%....High RDW.RDW in adultsSeverityMost notable causes> 26%Severe anisocytosisSideroblastic anemia2 more rows

How do you treat a high RDW CV?

How to lower RDWEating a balanced diet: A nutritious diet can help prevent deficiencies of iron, folate, and vitamin B12, which contribute to raised RDW levels. ... Stopping smoking: People who smoke have elevated RDW . ... Avoiding alcohol: Excessive alcohol can damage RBCs and decrease vitamin B12 and folate absorption.More items...

What does a low RDW CV mean?

What if my RDW count is low? A low RDW means that the red blood cells vary little in size. This could be due to the following: Macrocytic anemia. A blood disorder in which not enough RBCs are produced, but the ones that are present are large.

What is RDW SD?

Abstract. Background: The red cell distribution width (RDW) predicts mortality, including among cardiovascular, pulmonary, trauma, and other patients, and in the general population. RDW is the standard deviation (SD) of the red cell volume divided by the mean corpuscular volume (MCV).

What is RDW CV test?

The RDW test identifies the variation in size of your red blood cells. A red cell distribution width (RDW) test is one part of a complete blood count (CBC). That's a standard test doctors use to check your health by looking at the parts that make up your blood. RDW measures how the sizes of your red blood cells vary.

Elevated RDW and High MCV

If both numbers are high, you might be looking at a wide variety of potential problems, including immune hemolytic anemia, myelodysplastic syndrome...

Normal RDW and Normal MCV

Just because the numbers are “normal” doesn’t mean that all is well. On the contrary, a normal number for both of these can indicate anemia of chro...

Elevated RDW and Normal MCV

These numbers can be associated with a wide variety of conditions. These include sickle cell disease, chronic liver disease or myelodysplastic synd...

What does RDW tell you about your health?

Indication of RDW Result. There are many things your red blood cells can tell your doctor about your health. Here are just a few of the important points about red blood cell distribution width: In most cases, the RDW can help determine several points about your health, from your chances of developing an iron deficiency to different types ...

What is the RDW test?

The RDW is most helpful in alerting your doctor to the fact that there is a problem, which will then prompt him or her to call for further tests that will provide more detailed results. 1. Normal RDW and Low MCV.

What causes elevated RDW?

These numbers can be associated with a wide variety of conditions. These include sickle cell disease, chronic liver disease or myelodysplastic syndrome. Other problems might include early stages of folate, vitamin B12 or iron deficiency.

What is the difference between RDW and RDW-CV?

RDW-SD is an actual measurement, while RDW-CV involves some calculations using the RDW-SD deviation. Coupled with the MCV, the mean corpuscular volume, these numbers can indicate the patient's state of health, notes Med-Health.net. For example, if RDW is normal, but the MCV is low, the patient could be anemic.

What is RDW-CV?

What Are "RDW-CV" and "RDW-SD?". "RDW-CV" and "RDW-SD" are a measurement of the size of red blood cells, according to Med-Health.net. RDW-SD is an actual measurement, while RDW-CV involves some calculations using the RDW-SD deviation. Coupled with the MCV, the mean corpuscular volume, these numbers can indicate the patient's state of health, ...

What does it mean if your RDW is high?

If both are high, it could indicate any number of things, including low vitamin b12, liver problems or diseases such as myelodysplastic syndrome. ADVERTISEMENT.

Why is my RDW level higher than my MCV?

This can be caused by the beginning stages of a decrease in vitamin B12 or folic acid in the body. It can also be caused by the beginning stages of iron deficiency anemia (see above).

What is the RDW in hematology?

Red cell distribution width ( RDW) is a red blood cell parameter that measures variability of red cell volume/size (anisocytosis). Depending on the types of hematology analyzer instruments, RDW can be reported statistically as coefficient of variation (CV) and/or standard deviation (SD), RDW-CV and/or RDW-SD, respectively.

What is the condition where the RDW is high and the MCV is low?

Thalessemia intermedia is another type of blood disorder in which there is impaired production of one or more of the elements that make up hemoglobin. If the red blood cells are fragmented (broken) into smaller parts, this can cause the RDW to be high and the MCV to be low.

Why is my RDW low?

One reason for a low RDW level is macrocytic anemia. Macrocytic anemia is a blood disorder in which not enough red blood cells are produced, but the ones that are present are large. Another cause of a low RDW level is microcytic anemia.

What does it mean when your RDW is high?

A high RDW means that the red blood cells vary a lot in size. There are many possible reasons why the RDW level can be too high. To determine what the possible cause of a high RDW level is, a comparison is made to the mean corpuscular volume (abbreviated MCV).

Can hemolytic anemia cause high RDW?

Hemolytic anemia is a condition in which the red blood cells are destroyed earlier than they should be. The RDW and MCV levels can both be increased if there is too little Vitamin B12 or folic acid in the body. Another scenario is that the RDW level can be high, but the MCV level can be low.

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