JANUMET XR is a prescription medicine that contains 2 prescription diabetes medicines, sitagliptin (JANUVIA®) and extended-release metformin hydrochloride. JANUMET XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. JANUMET XR is not for people with type 1 diabetes.
What conditions does Janumet XR treat?
Side effects requiring immediate medical attention
- Anxiety
- blurred vision
- chills
- cold sweats
- confusion
- cool, pale skin
- depression
- dizziness
- fast heartbeat
- headache
What is the alternative of Janumet?
- Help your pancreas make more insulin
- Help your body more effectively use the insulin that it makes
- Help decrease the amount of sugar that your liver makes
What is the price for Janumet?
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What is Janumet prescribed for?
What is Janumet prescribed for? Janumet is prescribed to control the blood glucose levels in adult patients suffering from type II diabetes mellitus, as a first line treatment. How does Janumet work? Janumet is a combination of two drugs to treat diabetes mellitus. One of the drugs present in Janumet, Metformin, causes a decrease in the glucose production by the liver.
Can I take JANUMET XR twice daily?
You'll take one tablet twice per day. The maximum daily dose of Janumet is 100 mg sitagliptin/2,000 mg metformin. If you've never taken the drug metformin, your typical starting dosage of Janumet XR will be 100 mg sitagliptin/1,000 mg metformin. You'll take one tablet once per day.
What is JANUMET XR used for?
JANUMET XR (JAN-you-met XR) is a prescription medicine that contains 2 prescription diabetes medicines, sitagliptin (JANUVIA®) and extended-release metformin. JANUMET XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.
What is the best time of day to take JANUMET XR?
Take JANUMET XR 1 time each day with a meal to help to lower your chance of having an upset stomach. It is better to take JANUMET XR with your evening meal. Take JANUMET XR tablets whole. Do not break, cut, crush, or chew JANUMET XR tablets before swallowing.
Is JANUMET XR the same as JANUVIA?
Janumet is similar to Januvia, except it also contains metformin. So, in addition to stimulating the body to produce more insulin like Januvia does, the metformin in Janumet decreases the glucose produced by the liver and decreases the absorption of glucose by the intestines.
How good is JANUMET XR?
Janumet has an average rating of 6.0 out of 10 from a total of 54 ratings for the treatment of Diabetes, Type 2. 44% of reviewers reported a positive experience, while 31% reported a negative experience.
Is there a JANUMET XR?
Once-daily prescription JANUMET XR (JAN-you-met XR) tablets contain sitagliptin (the medicine in JANUVIA®) and extended-release metformin. JANUMET or JANUMET XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.
Can JANUMET XR be taken in the morning?
Take JANUMET XR one time each day by mouth with a meal to help lower your chance of having an upset stomach. It is better to take JANUMET XR with your evening meal. Take JANUMET XR exactly as your doctor tells you. Your doctor will tell you how many JANUMET XR tablets to take and when you should take them.
What are the long term side effects of Janumet?
JANUMET may cause serious side effects, including:See above section: "What is the most important information I should know about JANUMET?"Kidney problems, sometimes requiring dialysis.Low vitamin B12 (vitamin B12 deficiency). ... Low blood sugar (hypoglycemia). ... Serious allergic reactions. ... Joint pain. ... Skin reaction.
How quickly does JANUMET XR work?
The effect of Januvia (generic name: sitagliptin) on your blood sugar levels may begin quickly, within the first 1 to 2 weeks. You may start to see your blood sugar drop after just a few doses.
What can I take instead of JANUMET XR?
Dipeptidyl peptidase inhibitorsalogliptin (Nesina)linagliptin (Tradjenta)sitagliptin (Januvia)saxagliptin (Onglyza)
Does JANUMET XR cause weight gain?
Januvia (sitagliptin) is a type 2 diabetes medicine that can help you lower your blood sugar and reach your target goals, when used with diet and exercise. In studies it has not been shown to lead to weight gain when used alone or with metformin.
Is JANUMET XR the same as metformin?
Janumet (sitagliptin / metformin) is a combination of 2 different diabetic medications. Metformin, a biguanide, works by lowering the amount of sugar your liver releases into your blood and helps your body respond better to insulin.
Drug details
Janumet and Janumet XR contain the active ingredients sitagliptin and metformin. Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 inhibitors. Metformin belongs to a class of drugs called biguanides.
Effectiveness
For information about the effectiveness of Janumet and Janumet XR, see the “ Janumet and Janumet XR for diabetes ” section below.
Serious side effects
Serious side effects from Janumet and Janumet XR aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.
Drug forms and strengths
Janumet and Janumet XR come as oral tablets. They differ in the way they release the active drug:
Dosage for type 2 diabetes
For type 2 diabetes, the usual starting dosage of Janumet and Janumet XR depends on whether you’re already taking metformin. Metformin is a commonly prescribed drug for type 2 diabetes. It’s also one of the active ingredients in Janumet and Janumet XR.
What if I miss a dose?
If you miss a dose of Janumet or Janumet XR, take your missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip it. Then, take your next dose again on your regular schedule. If you aren’t sure whether to take a missed dose or skip it, talk with your doctor or pharmacist.
Will I need to take this drug long term?
Janumet and Janumet XR are meant to be taken as long-term treatments. If you and your doctor determine that Janumet or Janumet XR is safe and effective for you, you’ll likely take it long term.
What is in Janumet XR?
JANUMET (JAN-you-met) tablets contain 2 prescription medicines: sitagliptin (JANUVIA ®) and metformin. Once-daily prescription JANUMET XR (JAN-you-met XR ) tablets contain sitagliptin (the medicine in JANUVIA ®) and extended-release metformin. JANUMET or JANUMET XR can be used along with diet and exercise to lower blood sugar in adults ...
What is the side effect of JANUMET?
Metformin, one of the medicines in JANUMET and JANUMET XR, can cause a rare but serious side effect called lactic acidosis (a buildup of lactic acid in the blood), which can cause death. Lactic acidosis is a medical emergency that must be treated in a hospital.
How to contact FDA about JANUMET?
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Please read the accompanying Medication Guide for JANUMET® (sitagliptin and metformin HCl) tablets or JANUMET® XR (sitagliptin and metformin HCl extended-release) tablets, including the information about lactic acidosis, and discuss it with your doctor.
Does Janomet XR cause low blood sugar?
Your doctor may do blood tests to check your vitamin B 12 levels. If you take JANUMET or JANUMET XR with another medicine that can cause low blood sugar (hypoglycemia), such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher . The dose of your sulfonylurea or insulin may need to be lowered.
Can you stop taking Janomet XR?
If you have an allergic reaction, stop taking JANUMET or JANUMET XR and call your doctor right away or get emergency medical help. Tell your doctor if you are going to get an injection of dye or contrast agent for an x-ray procedure; JANUMET or JANUMET XR may need to be stopped for a short time.
Can you take Janomet XR without vomiting?
Stop taking JANUMET or JANUMET XR and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.
Can you take Janomet XR if you are allergic to Janomet?
Do not take JANUMET or JANUMET XR if you are allergic to any of the ingredients in JANUMET or JANUMET XR. Allergic reactions, which may be serious, including rash; hives; or swelling of the face, lips, tongue, and throat that may cause difficulty breathing or swallowing, can occur.
What is the difference between Januvia and Janumet?
Januvia and Janumet are two oral medications that can help lower blood sugar in adults with Type 2 Diabetes. Lowering blood sugar in this condition can save you from health problems in the future including kidney and heart issues. Januvia vs. Janumet The main acting ingredient in Januvia is Sitagliptin. Sitagliptin increases the production of GLP-1 and GIP hormones in your body. These hormones are responsible for helping to lower blood sugar and stimulating insulin production in your pancreas. This insulin is essential to keeping your blood sugar from getting too high or too low. Janumet is actually made up of two drugs, Sitagliptin and Metformin. Like in Januvia, the sitagliptin produces insulin, while the addition of Metformin helps to control the amount of glucose in your blood. Metformin lowers the amount of glucose you take in from your food and increases your body’s response to insulin. Some patients may already be taking Metformin on its own, but the addition of the Sitagliptin helps to lower blood sugar even more. If you are unable to take Metformin, Januvia can be a great and safer option. A balanced diet and regular exercise are key while taking both of these medications. Consult your doctor to develop a diet and exercise plan that will be easy to maintain long term. Neither medication should be used as a substitute for a healthy diet and consistent exercise. Side Effects Serious side effects may occur, which is why it is essential to talk to a doctor before taking either medication. Be sure to alert your doctor of previous medical conditions, especially pancreatitis, kidney problems, and liver problems. If you d Continue reading >>
What is Janumet used for?
What is Janumet used for? Janumet tablets are licensed for use in people with type 2 diabetes whose blood sugar is not controlled by the maximum to lerated dose of metformin alone, or who are already taking metformin and sitagliptin as separate tablets. They are also licensed for use in combination with a sulphonylurea (eg gliclazide) or a glitazone (eg pioglitazone), when one of these combined with metformin has not controlled blood sugar well enough. Janumet tablets may also be used in combination with insulin. How does Janumet work? Janumet tablets contain two active ingredients, metformin and sitagliptin. Metformin is a type of antidiabetic medicine known as a biguanide. It works in a number of ways to decrease the amount of sugar in the blood. Firstly, it reduces the amount of sugar produced by cells in the liver. Secondly, it increases the sensitivity of muscle cells to insulin. This enables these cells to remove sugar from the blood more effectively. Finally, it also delays absorption of sugar from the intestines into the bloodstream after eating. Sitagliptin is a type of antidiabetic medicine known as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It helps to reduce blood sugar levels by preventing the breakdown of two incretin hormones, called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). These hormones are normally produced naturally by the body in response to food intake. They stimulate the pancreas to produce insulin in response to increasing levels of glucose in the blood, and they also reduce the production of glucagon, which is a hormone that normally increases glucose production by the liver. These actions help control blood sugar levels. This combination of medicines helps control blood sugar levels both directly after Continue reading >>
Does Januvia cause weight loss?
Januvia (sitagliptin) doesnt usually cause weight loss or gain. (JASON REEKIE/ISTOCK/HEALTH)Januvia (sitagliptin) is a type 2 diabetes drug that was approved in 2006. It is also available in a combination pill (known as Janumet) that contains the drug metformin. They are the first drugs in a new class called the selective dipeptidyl peptidase-4 inhibitors, or DPP-4 inhibitors. Januvia has a big advantage in that it can stimulate insulin production in the body, and may be less likely to cause hypoglycemia than other drugs. If blood glucose falls too low, the drug ceases to stimulate insulin production. The disadvantage? The price. The drug is "very expensive," says Glenn Cunningham, MD, an endocrinologist and professor at Baylor College of Medicine in Houston. He notes that it costs $160 for a 30-day supply of 100-mg tablets. Nevertheless, "Januvia is becoming a much more popular drug," Dr. Cunningham says. It does not cause weight gain or weight loss, he explained, and is less likely to cause hypoglycemia. Continue reading >>
How to treat Janumet?
Janumet is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely. Your blood will need to be tested often. Store at room temperature away from moisture and heat.
What medications should I take before taking Janumet?
Tell your doctor if you use any of the following medications before taking Janumet: anti-seizure medications (including topiramate, zonisamide, acetazolamide, phenytoin, and others) anti-viral medications for HIV or AIDS; antipsychotic medications (especially chlorpromazine, pro chlorperazine, thioridazine, and others);
Can you take Janumet if you are allergic to metformin?
You should not use Janumet if you are allergic to metformin or sitagliptin (Januvia), or if you have severe kidney disease. To make sure Janumet is safe for you, tell your doctor if you have ever had: kidney disease (your kidney function may need to be checked before and while you are taking this medicine);
Is Janumet used for diabetes?
Janumet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Janumet is not used to treat type 1 diabetes.
Does Janumet dissolve in the body?
Janumet tablets may not completely dissolve in the body. Part of the tablet may appear in your stool. This is a normal side effect of Janumet and will not make the medicine less effective. Call your doctor if you see a tablet in your stool several times.
Does Janumet cause a rash?
Janumet side effects. Get emergency medical help if you have signs of an allergic reaction to Janumet: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Can you take Janumet while pregnant?
Follow your doctor's instructions about using Janumet if you are pregnant or you become pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Having high blood sugar may cause complications in both the mother and the baby.
What is the difference between metformin and janumet?
What's the difference between metformin vs. Janumet? Metformin and Janumet ( metformin and sitagliptin) are used to treat type 2 diabetes. Metformin is also used to treat polycystic ovaries and weight gain due to medications used for treating psychoses.
Does Tagamet increase metformin?
Cimetidine ( Tagamet ), by decreasing the elimination of metformin from the body, can increase the amount of metformin in the blood by 40%. This may increase the frequency of side effects from metformin.
