pledget. A small flat absorbent pad used to medicate, protect, or absorb drainage from a wound or sore. Similarly, who invented medical stitches? The original sutures were made from biological materials, such as catgut suture and silk. These absorbed bodily fluids and could be foci of infection.
What does pledget mean in medical terms?
Medical Definition of pledget : a compress or small flat mass usually of gauze or absorbent cotton that is laid over a wound or into a cavity to apply medication, exclude air, retain dressings, or absorb the matter discharged.
What is a pledget made of?
Pledgets or felts are non-absorbable materials composed of poly-tetra fluoro ethylene (PTFE) and are are indicated for use as non-absorbable suture supports when there is a chance of sutures tearing through body tissues. Polyester sutures are not subject to degradation and retain tensile strength indefinitely in vivo.
Can you use a 10% solution with a conjunctival pledget?
It has been suggested that the practice of using a 10% solution either by irrigation with a conjunctival pledget or injection subconjunctivally should be discouraged (4). To obtain salivary cortisol measurements, the infant was allowed to suck on a dental pledget for 1 minute.
What is this medicine?
CLINDAMYCIN (KLIN da MYE sin) is a lincosamide antibiotic. It is used on the skin to stop the growth of certain bacteria that cause acne.
How should I use this medicine?
This medicine is for external use only. Wash hands before and after use. Wash affected area and gently pat dry. Remove from foil right before use. Do not use if the seal is broken. More than one pledget may be used to treat the affected area. Each pledget should be used only one time and then thrown away.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What should I watch for while using this medicine?
Your acne should start to get better within about 6 weeks. Complete improvement may take longer. Tell your doctor or health care professional if you do not see any improvement.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
DESCRIPTION
Clindamycin Phosphate Topical Solution USP, 1% contains clindamycin phosphate, at a concentration equivalent to 10 mg clindamycin per milliliter. Each Clindamycin Phosphate Topical Solution pledget applicator contains approximately 1 mL of topical solution.
CLINICAL PHARMACOLOGY
Although clindamycin phosphate is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin.
INDICATIONS AND USAGE
Clindamycin Phosphate Topical Solution USP, 1% is indicated in the treatment of acne vulgaris. In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate. (See CONTRAINDICATIONS , WARNINGS and ADVERSE REACTIONS.)
CONTRAINDICATIONS
Clindamycin Phosphate Topical Solution USP, 1% is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
WARNINGS
Orally and parenterally administered clindamycin has been associated with severe colitis which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface.
PRECAUTIONS
General: Clindamycin Phosphate Topical Solution USP, 1% contains an alcohol base which will cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin, mucous membranes), bathe with copious amounts of cool tap water.
ADVERSE REACTIONS
In 18 clinical studies of various topical clindamycin formulations of clindamycin phosphate using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatologic events [see table below].
