A very powerful and potentially addictive opioid analgesic medication synthesized from thebaine
Thebaine
Thebaine, also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai, an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effect…
Free base
Free base (freebase, free-base) refers to the conjugate base (deprotonated) form of an amine, as opposed to its conjugate acid salt form. The amine is usually an alkaloid, such as nicotine, cocaine, morphine, and amphetamine.
Oxycodone
This medication is used to help relieve moderate to severe pain.
Full Answer
What is freebase cocaine?
"Freebase" refers to the smokable form of cocaine, which comes in the form of crack cocaine, a hard, rock-like substance. Powder cocaine is actually cocaine hydrochloride, which is a water-soluble salt form of the drug.
Why do people Freebase drugs?
Similar to cocaine, people freebase to get a dose of a drug in its purest form, making it more potent. Since nicotine and opioids are already in smokable forms, the only reason users freebase these drugs is to increase their potency.
How long does freebase cocaine stay in your system?
Since freebase cocaine is absorbed through the membranes of the lungs, it enters the bloodstream and the brain within 10-15 seconds. Once it reaches the brain, there is an intense feeling of euphoria followed by an extreme high lasting about 30 minutes.
What are the most commonly free-based drugs?
Cocaine is the most commonly freebased drug. However, it is possible to freebase other drugs, including nicotine and opioids. Similar to cocaine, people freebase to get a dose of a drug in its purest form, making it more potent.
What drug did Demi Lovato use?
The dealer — who apparently laced the drugs with fentanyl — is believed to have left Lovato’s home when he noticed she was in bed, breathing heavily.
What happens when you freebase a drug?
When people freebase, they remove the salt and extract just the pure form of the drug, Alan says. Often people will take that pure form, heat it (usually on foil), and inhale the vapors, addiction specialist Neeraj Gandotra, MD, chief medical officer at Delphi Behavioral HealthGroup, tells Yahoo Lifestyle.
Did Demi Lovato overdose?
More details are emerging about the night Demi Lovato apparently overdosed in late July. In a new report, TMZ cites sources who allege that the singer took oxycodone laced with fentanyl. (The reports have not been confirmed.)
Is Demi Lovato a drug?
Lovato was later administered Narcan, a drug that can treat a narcotic overdose in an emergency situation. Whether the 25-year-old freebased or not remains to be seen. But either way, the practice is highly dangerous.
Is fentanyl a bad drug?
Fentanyl is also one of the most potent opioids on the market, and if someone doesn’t have a tolerance to it, that person can “rapidly” go into respiratory distress and arrest, Alan says.
Is Demi Lovato in the hospital?
Fentanyl is also one of the most potent opioids on the market, and if someone doesn’t have a tolerance to it, that person can “rapidly” go into respiratory distress and arrest, Alan says. Lovato reportedly spent two weeks in the hospital and is currently seeking treatment for drug addiction.
Does smoking help with liver disease?
Not only that, smoking or snorting a drug bypasses your liver, which will help filter out some of the drug before it reaches the rest of your body if you took it orally, Alan says — as a result, it’s more likely that a person will overdose.
Why do people freebase?
Similar to cocaine, people freebase to get a dose of a drug in its purest form, making it more potent. Since nicotine and opioids are already in smokable forms, the only reason users freebase these drugs is to increase their potency. Freebasing nicotine makes it easier for the drug’s chemicals to cross the body’s membranes.
What is freebasing in drug use?
Freebasing is a method of using a drug, usually cocaine, to increase its potency. It is a clear sign of drug abuse. In this method, the user puts the base form of the drug in a glass pipe and heats it until it boils. Then they inhale the vapors for a faster, more intense high. Cocaine is typically snorted or applied to the gums.
What is the end product of smoking cocaine?
Instead of using ether, people who want to smoke cocaine use baking soda to remove the hydrochloride in cocaine. The end product is smokable crystal rocks. This form of cocaine is known as crack. Now that crack is far more commonly used than freebasing, the terms are often used interchangeably.
How to make cocaine freebase?
It’s also possible to create the freebase form of cocaine by boiling the drug with sodium bicarbonate. The goal is to make the drug purer, giving it more potency. Once the original product was “freed from its base,” it was heated and the vapors inhaled.
What are the two chemicals that make up cocaine?
Cocaine is made from two chemicals: Alkaloid (base) Hydrochloride (salt) These chemicals make up the drug’s base.
Why do cigarettes have ammonia in them?
Cigarette companies add ammonia in the form of diammonium phosphate to nicotine to make the drug more bioavailable to the brain, lungs, and tissues. One of the reasons why smoking cigarettes is such a health risk is because commercial cigarettes are not just tobacco rolled in paper.
Is methamphetamine a freebase?
Powder methamphetamine is the hydrochloride salt form of meth. It is smokable as is. Crystal meth is the crystallized version of methamphetamine. It is purer and easier to smoke in this form, but it is not truly considered a freebase. Actual methamphetamine freebase is an oil, which is an uncommon form of the drug.
Why is freebase cocaine dangerous?
Part of the reason freebase cocaine is so dangerous is that it is nearly pure. Many types of drug are mixed with something, making them less potent. Freebase cocaine is both pure and smoked to ensure a quick onset—both of these factors increase the risk of overdose.
What is aftercare for cocaine?
Aftercare is also important in treating cocaine abuse and addiction. Seeking out support groups, taking part in 12-Step programs, and living in drug-free, residential communities are all viable aftercare options for those recovering.
Is there a drug for cocaine addiction?
There are currently no medications available for the treatment of cocaine abuse. However, several forms of therapy have proven effective. The NIDA states that one of the best forms of treatment available is cognitive-behavioral therapy.
Can freebase cocaine cause malnourishment?
Abuse of freebase cocaine can result in several long-term effects on health. Malnourishment can occur with lack of appetite, both from the effects of cocaine and from binges. During a binge, a person abusing cocaine may take several consecutive doses. This allows the person to maintain a continuous high.
What is freebase cocaine?
Freebase cocaine is essentially the “base” form of the drug – the drug in its solid form. Freebasing cocaine is the process of freeing the cocaine base from the salt form in which cocaine is naturally found. While crack cocaine is produced by mixing the original cocaine with a combination of water and baking soda, ...
Why is it dangerous to overdose on freebase?
Overdose is also likely because of the intensity and sudden onset of freebase cocaine’s effects. The risk of overdose is compounded if use of freebase cocaine is combined with use of any other substances, such as alcohol.
How long does it take for cocaine to get into your system?
Since freebase cocaine is absorbed through the membranes of the lungs, it enters the bloodstream and the brain within 10-15 seconds. Once it reaches the brain, there is an intense feeling of euphoria followed by an extreme high lasting about 30 minutes.
What are the long term effects of freebase?
Long-term effects of freebase cocaine use include mood changes, irritability, restlessness, depression, anxiety, paranoia, and hallucinations. In addition, smoking the substance brings various negative health effects, such as respiration issues, damage to the lungs and mouth, and a higher likelihood of developing various cancers.
What are the risks of freebasing?
Seizures. Asthma and other respiratory issues. Other risks of freebasing include burns to the face or fingers from glass pipes or matches and lighters during use. Additionally, users are prone to injuries from accidents or violence while under the influence.
Is cocaine 100 percent pure?
The result is a form of cocaine that is almost 100 percent pure. In this form, it has a low melting point, which makes it easier to smoke. Freebase cocaine is not soluble in water, so it is difficult to melt and inject the drug. There are various methods for freebasing cocaine. Typically, it involves using a small glass pipe.
Does cocaine cause withdrawal symptoms?
While cocaine tends produce more psychological withdrawal symptoms than physical, the effects of these psychological symptoms can be intense. Withdrawal symptoms include: Those who smoke freebase cocaine, as well as crack, are at higher risk for overdose because it is pure cocaine, which makes it extremely potent.
Is freebase more addictive than cocaine?
Freebase is extremely addictive, even more so than powdered cocaine, and users can quickly become hooked. Smoking cocaine also doesn’t provide as much control over how much of the drug is consumed, which can lead to overdose in the worst-case scenario. Quitting on your own is inadvisable because withdrawal can be taxing to the brain, impairing both its function and your mental health. To safely and effectively quit using freebase cocaine, you can rely on the innovative treatment program provided by Clear Sky Recovery. Ibogaine is the key component of our program, with the goal of giving clients a safe, effective, and gentle detox from drugs or alcohol. Our experienced medical team expertly customizes treatment plans for each client, and constant and compassionate clinical care ensures everyone’s comfort during their stay. Contact us today to get more information and learn how we can help.
Is crack cocaine addictive?
Smoking cocaine, whether in freebase or crack form, can be detrimental to a person’s health. It is considered the most addictive form of cocaine because it reaches the brain more quickly than if the cocaine is injected, snorted, or dissolved in the mouth. On top of that, the high—already propulsive with powdered cocaine—is magnified, as is the crash when the rush wears off. The high from freebasing or smoking crack is brief, about five to 10 minutes, which is shorter than when cocaine is taken in other ways. This may cause people to binge on the drug to get a sustained high. Unsurprisingly, there is a similar elevated intensity in drug cravings when freebasing.
What to avoid when lying down?
Avoid grapefruit juice, grapefruit products, Seville oranges (used to make orange marmalade) and tangelos (a tangerine-grapefruit cross) due to possible food-drug interactions.
How long does Oxycodone last?
Extended-release formulations of oxycodone (Oxycontin) last for 12 hours.
What is Oxycodone used for?
Last updated on Sep 29, 2020. 1. How it works. Oxycodone is a morphine-like, strong pain-relieving medicine used for the relief of severe pain that is unresponsive to less potent pain-relieving medicines (analgesics). Oxycodone is relatively selective for ...
What happens if you stop taking Oxycodone?
Abrupt discontinuation of oxycodone in a person who has become physically dependent on it may lead to a withdrawal syndrome and symptoms such as restlessness, pupil dilation, watery eyes and a runny nose, sweating, muscle aches, insomnia, irritability, and gastrointestinal complaints.
What medications affect serotonin?
other medications that affect serotonin, such as amphetamines, fentanyl, lithium, tramadol, triptans (eg, almotriptan, eletriptan, or sumatriptan), or St. John's Wort. Avoid grapefruit products and drinking alcohol or taking illegal or recreational drugs while taking oxycodone.
Does Oxycodone cause rash?
Oxycodone is less likely to cause an itchy rash compared to other opioids such as morphine. Oxycodone does not have a ceiling effect for analgesia, which means that if a person finds that oxycodone is no longer controlling their pain, a higher dosage should provide pain relief.
Is Oxycodone a narcotic?
Oxycodone belongs to the group of drugs known as opioids or opioid analgesics. Oxycodone may also be called a narcotic analgesic. 2. Upsides. Effective against moderate-to-severe pain, including cancer-related pain. Longer-lasting (extended-release) tablets are available (brand name OxyContin).
tilopa Silver Member
Swim posted this in another forum which swim now thinks was the wrong place as this forum on chemistry is probably the better place. I am trying to figure out how to move it, but until then I will post this here as well and try and delete the other.
Docta Idiot Savant Gold Member Donating Member
This is not the place for specialized drug questions, this forum is basic chem only.
tilopa Silver Member
It certainly has a higher bioavailability when smoked. But even if it did not I was not asking which was the higher bioavailability. Sometimes smoking just give one a better high.
t3knology Newbie
From my experience, I've never felt anything when smoking any form of oxycodone. That doesn't mean that it doesn't work, it's possible that my tolerance was too high to feel the amount that I had smoked when the people I was with were feeling great.
tilopa Silver Member
The point I am trying to make is that when people talk about smoking oxy's they are referring to talking a pill, crushing it up, putting it on foil, and heating the foil with a lighter while sucking up the fumes with a straw (chasing the dragon), this is not freebasing by the way as many people call it.
tycon69 Silver Member
Cocaine is a weakly alkaline compound (an " alkaloid "), and can therefore combine with acidic compounds to form various salts. Oxycodone does not do this and is already in it's "freebase" form in the medication. Morphine, on the other hand, exists as a salt, most commonly morphine sulfate.
sm0k3d Newbie
You doesn't need to do anything special to smoke it. If you have the old OC 80s or anything similar all that needs to be done is take the coating off with a damp towel and rub it off. Break it in half (or quarters), put it on the foil and then light it from the bottom and suck up the smoke.
