VANCOMYCIN TROUGH
| ORDERING INFORMATION: | |
| Specimen type: | Serum or plasma. |
| Preferred collection container: | Stat/Line draws: 3 mL green /yellow-top ... |
| Alternate Collection Container: | 6 mL red-top (plain, non-serum separator ... |
What color tube is used for vancomycin trough?
3 rows · · Vancomycin is an antibiotic that is used to treat serious infections caused by Gram-positive ...
What color lab tube for Vanc trough?
Minimum Volume 0.3 mL Container Red-top tube, lavender-top (K2- or K3- EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel.
Why do we check Vanco trough?
What tube is a Vanco trough drawn in? MUST be collected in a red top tube NO GEL; For the Vancomycin, Total, 2 specimens are required, 1 peak specimen and 1 trough specimen.
When to order Vanc trough?
Preferred: Gold top (SST) tube, Red top (serum) tube, or Green top (lithium heparin) tube Alt: Lavender top (EDTA) tube. Volume. Pref. Vol.: 1.0 mL serum or plasma Min. Vol.: 0.5 mL serum or plasma. Collection Instructions • Collection Timing: Draw trough sample immediately before next dose • Routine venipuncture
What is a vancomycin trough?
When a person takes a dose of vancomycin, the amount in the blood rises for a period of time, peaks, and then begins to fall, usually reaching its lowest level, or trough, just before the next dose. The next dose is timed to coincide with the falling concentration of the drug in the blood.
When do you draw vancomycin trough levels?
Trough: just before 4th dose of a new regimen (prior to 3rd dose for dosing intervals ≥ 24 hours or changing renal function) - Trough levels should be obtained within 30 minutes before the next scheduled dose. - Weekly vancomycin levels should be obtained for long-term vancomycin use with stable renal function. i.
Why is a vancomycin trough drawn?
Vancomycin blood levels are drawn at timed intervals to measure drug levels during treatment. Vancomycin has a narrow therapeutic index, which is the ratio between the toxic and effective dose of medication.
How do you collect vancomycin trough?
Vancomycin, Total - Collect the Peak specimen 1-2 hours after completion of a 60 minute IV infusion and Collect the Trough specimen just before administering next dose. Reject due: Specimens collected in SST (serum seporator tubes). Special Instructions: CANNOT be run from SST tube.
How do you administer vancomycin IV?
Vancomycin should be infused slowly in a dilute solution (2.5 to 5.0 mg/ml) at a rate no greater than 10 mg/min and over a period not less than 60 minutes to avoid rapid infusion-related reactions. Stopping the infusion usually results in a prompt cessation of these reactions.
Why is vancomycin given IV?
However, the drug has poor oral bioavailability and is broken down in the stomach and intestines before it can enter the bloodstream to treat systemic infections. As a result, for systemic infections, vancomycin is given intravenously (IV) for better efficacy.
What is C trough?
In medicine and pharmacology, a trough level or trough concentration (Ctrough) is the concentration reached by a drug immediately before the next dose is administered, often used in therapeutic drug monitoring.
What class of antibiotics is vancomycin?
Vancomycin is in a class of medications called glycopeptide antibiotics. It works by killling bacteria in the intestines. Vancomycin will not kill bacteria or treat infections in any other part of the body when taken by mouth. Antibiotics will not work for colds, flu, or other viral infections.
Why are peak and trough levels drawn?
What do peak and trough levels indicate? Peak and trough levels indicate drug levels in an individual's body. A peak is the highest level of a medication in the blood, while a trough level indicates the lowest concentration.
What is the purpose of obtaining the trough level?
To adequately evaluate the appropriate dosage levels of many drugs, the collection and testing of specimens for trough and peak levels is necessary. The trough level is the lowest concentration in the patient's bloodstream, therefore, the specimen should be collected just prior to administration of the drug.
What test do you use to order trough and peak?
Peak levels should be ordered using test 070327. Trough levels should be ordered using test 070328. Peak and trough levels may be ordered together as a profile on the same request form using test 717314. Please label tubes appropriately as “peak” and “trough.”
Can you use a gel carrier tube for EDTA?
Red-top tube, lavender-top (K2- or K3- EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
What happens when you put whole blood in a tube with anticoagulant?
when you put whole blood in a tube with anticoagulant (like purple or blue tops), that keeps it from clotting, so you can do things like look at hgb/hct, and cbc.
What color top is used for lab?
Call the lab.....but we use light green or yellow top.
