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uniprot database

by Emil Graham Published 4 years ago Updated 3 years ago

What is UniProt database?

The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).02-Feb-2021

Is UniProt a primary database?

UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects....UniProt.ContentPrimary citationUniProt ConsortiumAccessData formatCustom flat file, FASTA, GFF, RDF, XML.Websitewww.uniprot.org www.uniprot.org/news/16 more rows

Is UniProt a secondary database?

Hybrid databases and families of databases Many data resources have both primary and secondary characteristics. For example, UniProt accepts primary sequences derived from peptide sequencing experiments.

What type of knowledge database is UniProt?

protein sequence databaseUniProtKB/Swiss-Prot (reviewed) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions.22-Nov-2021

What is the use of UniProt?

UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.

How reliable is UniProt?

UniProtKB encompasses several individual protein sequence resources that are depicted on this page. If you are talking about a sequence that is from SwissProt (manually reviewed/curated sequences) or UniRef100 clusters then that sequence is likely perfectly accurate.26-Oct-2018

What are the stages of UniProt database?

This process consists of 6 major mandatory steps: (1) sequence curation, (2) sequence analysis, (3) literature curation, (4) family-based curation, (5) evidence attribution, (6) quality assurance and integration of completed entries.10-Apr-2018

How many sequences are in UniProt?

INTRODUCTION Release 2021_04 of 29-Sep-2021 of UniProtKB/TrEMBL contains 225013025 sequence entries, comprising 78379501201 amino acids. 12728037 sequences have been added since release 2021_03, the sequence data of 31110 existing entries has been updated and the annotations of 93040713 entries have been revised.

What is a UniProt number?

An accession number (AC) is assigned to each sequence upon inclusion into UniProtKB. Accession numbers are stable from release to release. If several UniProtKB entries are merged into one, for reasons of minimizing redundancy, the accession numbers of all relevant entries are kept.10-Apr-2018

Is Swiss-Prot and UniProt same?

Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. UniProtKB/Swiss-Prot is now the reviewed section of the UniProt Knowledgebase.10-Apr-2018

Is UniProt and Swiss-Prot same?

UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. ... UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.

Is Swiss-Prot a primary database?

Hint: A primary database is one that makes information available to the public. The secondary databases take this information on sequences to then add layers to the existing DNA sequence and protein sequence data. Complete answer: SWISS PROT is a protein sequence database.

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