What does blast do in UniProt?
If you select the Blast tab of the toolbar from a UniProtKB, UniRef or UniParc entry page, the current sequence is prefilled in the form. Jobs have unique identifiers, which (depending on the job type) can be used in queries (e.g. to get the intersection of two sequence similarity searches).
Is Swiss-Prot and UniProt same?
Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. UniProtKB/Swiss-Prot is now the reviewed section of the UniProt Knowledgebase.
How do I download UniProt?
UniProt is updated every eight weeks (see FAQ on how to be notified automatically of updates). You can download small data sets and subsets directly from this website by following the download link on any search result page. For downloading complete data sets we recommend using ftp.uniprot.org.
What is the UniProt Knowledgebase?
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation.
Who created Swiss-Prot?
SWISS-PROT (1) is an annotated protein sequence database, which was created at the Department of Medical Biochemistry of the University of Geneva and has been a collaborative effort of the Department and the European Molecular Biology Laboratory (EMBL), since 1987.
Is UniProt a secondary database?
Hybrid databases and families of databases Many data resources have both primary and secondary characteristics. For example, UniProt accepts primary sequences derived from peptide sequencing experiments.
What does UniProt stand for?
The Universal Protein ResourceThe Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
How do I extract information from UniProt?
Select the Retrieve/ID mapping tab of the toolbar and enter or upload a list of identifiers (or gene names) to do one of the following: Retrieve the corresponding UniProt entries to download them or work with them on this website.
How do I get my protein sequence from NCBI?
A NUCLEOTIDE OR PROTEIN SEQUENCEUse the NCBI BLAST service to perform a similarity search.For a nucleotide sequence select the nucleotide blast service from the Basic BLAST section of the BLAST home page. ... Click the BLAST button to run the search and identify matching sequences.
Why is UniProt important?
UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.
How many proteomes does UniProt have?
Complete Proteome Detector (CPD) A valid group is required to contain a minimum of thirty proteomes and all proteomes in the group must be in the same taxonomic class or more closely related.
What are the major features of UniProt?
THE UNIPROT KNOWLEDGEBASE (UNIPROT)High-quality annotation. ... Manual annotation by curators based on literature and sequence analysis. ... Automatic classification and annotation. ... High-quality Automated and Manual Annotation of microbial Proteomes (HAMAP) ... Standardized nomenclature and controlled vocabularies.More items...