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trembl database

by Rowan Ferry Published 3 years ago Updated 2 years ago

Introduction TrEMBL is a computer-annotated protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank. TrEMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet integrated in SWISS-PROT.01-Jan-1999

What is TrEMBL?

Introduction TrEMBL is a computer-annotated protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank. TrEMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet integrated in SWISS-PROT.

How do I contact TrEMBL?

TrEMBL Release Notes Release 9, January 1999 EMBL Outstation European Bioinformatics Institute (EBI) Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SD United Kingdom Telephone: (+44 1223) 494 444 Fax: (+44 1223) 494 468 Electronic mail address: DATALIB@EBI. AC. UK WWW server: http://www. ebi. ac.

How do I access the UniProtKB/TrEMBL sequence database?

SRS - is the easiest and simplest method available to quickly access the UniProtKB/TrEMBL sequence database. UniProt Power Search - Provides full text, advanced search, set manipulation and search filtering on the Universal Protein Resource.

What's new in UniProtKB/TrEMBL 2019_10?

INTRODUCTION Release 2019_10 of 13-Nov-2019 of UniProtKB/TrEMBL contains 181787788 sequence entries, comprising 60779914732 amino acids. 6122937 sequences have been added since release 2019_09, the sequence data of 900 existing entries has been updated and the annotations of 39948743 entries have been revised. This represents an increase of 4%.

What is the difference between SWISS-PROT and TrEMBL?

TrEMBL consists of entries in a SWISS-PROT format that are derived from the translation of all coding sequences in the EMBL nucleotide sequence database, that are not in SWISS-PROT. Unlike SWISS-PROT entries those in TrEMBL are awaiting manual annotation.

What is SWISS-PROT database?

SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, structure of its domains, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases.

How do I access TrEMBL?

There are multiple sites on the Web that can access the Swiss-Prot/TrEMBL and retrieve the database. Its main sites are the ExPASy Molecular Biology website (http://www.expasy.org/) and the European Institute of Bioinformatics (EBI) website (http://www.ebi.ac.uk/swissprot/).

Is UniProt a primary database?

Uniprot was originally formulated as a primary database for protein sequences and functional annotation based on experimental evidence. Nowadays it combines a network of sister databases centralising all levels of annotation produced for protein sequences.

Is SWISS-PROT a secondary database?

Hint: A primary database is one that makes information available to the public. The secondary databases take this information on sequences to then add layers to the existing DNA sequence and protein sequence data. Complete answer: SWISS PROT is a protein sequence database.

What does SWISS-PROT entry contain?

SWISS-PROT contains the information about the name and origin of the protein, protein attributes, general information, ontologies, sequence annotation, amino acid sequence, bibliographic references, cross-references with sequence, structure and interaction databases, and entry information.

What is TrEMBL in bioinformatics?

Introduction TrEMBL is a computer-annotated protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank. TrEMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet integrated in SWISS-PROT.01-Jan-1999

What is about TrEMBL?

TrEMBL consists of computer-annotated entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDS) in the EMBL nucleotide sequence database, except for CDS already included in SWISS-PROT.

What are bioinformatics prints?

From Wikipedia, the free encyclopedia. In molecular biology, the PRINTS database is a collection of so-called "fingerprints": it provides both a detailed annotation resource for protein families, and a diagnostic tool for newly determined sequences.

Is UniProt and Swiss-Prot same?

UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.

What kind of database is UniProt?

The UniProt Knowledgebase (UniProtKB) is an expertly curated database, a central access point for integrated protein information with cross-references to multiple sources. The UniProt Archive (UniParc) is a comprehensive sequence repository, reflecting the history of all protein sequences (1).

Why is UniProt used?

The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. EMBL-EBI and SIB together used to produce Swiss-Prot and TrEMBL, while PIR produced the Protein Sequence Database (PIR-PSD). ...02-Feb-2021

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