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symport

by Felix Emmerich Published 3 years ago Updated 3 years ago

[ sĭm′pôrt′ ] n. The transport of two different molecules or ions in the same direction through a membrane using a common carrier mechanism.

What is symport?

Symport is a type of transmembrane protein involved in secondary active transport. Transporting two type molecules or ions in the same direction at once across the membrane is a specialty of the symporter.

What is symport and antiport?

Symport is a transmembrane protein molecule in the cell membrane which transports two types of molecules or ions in the same direction across the membrane. Antiport is a transmembrane protein in the cell membrane which transports two types of molecules or ions in opposite directions across the membrane.

What is the difference between uniport and symport?

Uniport refers to an integral membrane protein, which transports a single type of substrate species across the cell membrane. And, symport refers to another integral membrane protein involved in the transport of two different molecules in the same direction through the cell membrane.

How does a symporter work in a cell?

How it works. A symporter is an integral membrane protein that is involved in the transport of many differing types of molecules across the cell membrane. The symporter works in the plasma membrane and molecules are transported across the cell membrane at the same time, and is, therefore, a type of cotransporter.

What is symport and antiport?

Symport: move together in the same direction. Antiport: move in opposite directions in the form of an exchange.

What is an example of symport?

Symport is a form of active transport. It uses the downhill movement of solute species from high concentration to lower for the movement of other molecules uphill from low to high concentration, which takes place against the electrochemical gradient. An example is the glucose symporter SGLT1.

What is symport movement?

Proteins that move two molecules in the same direction across the membrane are called symports (also called synporters, synports, or symporters). If two molecules are moved in opposite directions across the bilayer, the protein is called an antiport. Proteins involved in moving ions are called ionophores.

What does symport mean in biology?

Definition. Protein involved in the transport of solutes across a biological membrane in one direction, which depends on the transport of another solute in the same direction.

What is symport short answer?

Symport is the type of transport in which two different molecules can move through a membrane in same direction by using a common carrier mechanism. The transporter is called a symporter which is an integral protein and it works in the cell membrane the molecules to transport across the membrane at the same time.

What is uniport transport?

A uniporter is a membrane transport protein that transports a single species of substrate (charged or uncharged) across a cell membrane. It may use either facilitated diffusion and transport along a diffusion gradient or transport against one with an active transport process.

What is symporter and cotransporter?

A cotransporter (symporter) is a carrier protein that allows the transport of two different species (a solute and an ion) from one side of the membrane to the other at the same time [44,45].

How do symport proteins work?

Symporters are proteins that simultaneously transport two molecules across a membrane in the same direction. The most widely held model for this process has the molecules binding to the transport protein that is exposed on the external surface of the membrane.

What are symport and antiport give examples?

In antiport system, two molecules move in opposite directions. Examples of symport systems include sodium sugar pump and hydrogen sugar pump. Examples of antiport systems include sodium potassium pump, sodium calcium exchanger, bicarbonate chloride pump, sodium hydrogen antiporter, etc.

What are symport antiport and uniport membrane transport?

A protein involved in moving only one molecule across a membrane is called a uniport. Proteins that move two molecules in the same direction across the membrane are called symports. If two molecules are moved in opposite directions across the bilayer, the protein is called an antiport.

What is a symport?

Symport is a type of transmembrane protein involved in secondary active transport. Transporting two type molecules or ions in the same direction at once across the membrane is a specialty of the symporter. Small molecules such as sugar, Na + are transported across the membrane by symporters in the membrane.

What is the difference between antiport and symport?

The key difference between symport and antiport is that in symport, two molecules or ions are transported in the same direction across the membrane while in antiport, two molecules or ions are transported in opposite directions across the membrane.

What is an antiporter?

Antiport molecules or Antiporter is a transmembrane protein in the cell membrane. It is involved in the secondary active transport of molecules across the cell membrane. Antiport proteins are able to cotransport two different molecules or ions across the membrane in opposite directions at once. When one molecule enters the cell, ...

What is the function of a symporter?

The symporter works in the plasma membrane and molecules are transported across the cell membrane at the same time, and is, therefore, a type of cotransporter.

Why is the symporter called the cotransporter?

The transporter is called a symporter, because the molecules will travel in the same direction in relation to each other. This is in contrast to the antiport transporter.

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Please cite us

Hume, Benjamin CC, Edward G. Smith, Maren Ziegler, Hugh JM Warrington, John A. Burt, Todd C. LaJeunesse, Joerg Wiedenmann, and Christian R. Voolstra. "SymPortal: A novel analytical framework and platform for coral algal symbiont next‐generation sequencing ITS2 profiling." Molecular ecology resources 19;1063-1080 (2019).

What is an antiport?

Antiport is the second type of cotransporter, which uses secondary active transport mechanisms. In contrast to symport, antiport transports the two different molecules in opposite directions. For example, N general, Na/H antiporter, Na/Ca exchanger, etc. are antiports. Of these, many cells use Na/Ca exchanger removes cytoplasmic calcium by exchanging one calcium ion for three sodium ions.

How does a uniport work?

Usually, a uniport works by binding to one molecule of the substrate at a time while the opening of the channels may occur in response to a stimulus and allow the free flow of specific molecules. Importantly, uniports participate in biological processes such as transmitting action potentials in neurons.

What is the difference between antiport and uniport?

The main difference between uniport, symport, and antiport is that uniport moves molecules across the membrane independent of other molecules, and symport moves two types of molecules in the same direction, but antiport moves two types of molecules in opposite directions.

What type of transport does Uniport use?

Uniport uses primary active transport, but both symports and antiports use secondary active transport.

Is Na/H an antiporter?

Furthermore, all channel proteins are the examples of uniports, and Na/glucose symporter is an example of a symport, while Na/H antiporter is an example of antiport. In brief, uniport, symport, and antiport are the three types of integral membrane proteins, which participate in moving molecules across the cell membrane.

Is SGLT1 a symport?

For example, SGLT1 in the intestinal epithelium is a symport. It transports sodium ions and glucose across the luminal membrane of the epithelial cells in order to be absorbed into the bloodstream. In addition to that, Na+/K+/2Cl− symporter in the loop of Henle is another example of sym port.

Does symport transport energy?

Thereby, it uses energy from ATP for the transport of molecules. In contrast, both symport and antiport use secondary active transport and the driving force of molecules is the electrochemical gradient. In addition to that, both transport two different types of molecules at the same time. However, symport transports two types ...

Quel est le rôle de la protéine symport?

Une protéine symport est un type de protéine transporteuse qui permet le passage à travers la membrane cellulaire de deux molécules différentes à la fois. Il faut cependant que les deux molécules soient au contact du symport pour que celui-ci agisse.

Quelle est la fonction des protéines symports?

Les protéines symports sont responsables en partie (avec les protéines uniports ) de la diffusion facilitée des solutés au travers des membranes des cellules et des organites.

Function

Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. The energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) which is used to drive solute accumulation against a concentration gradient.

Substrate Affinity in Humans

In the human homologue ( hSGLT1 ), H + can replace Na +, but the apparent affinity for glucose reduces 20x from 0.3 mM to 6 mM. The apparent affinity for H + is 6 μM, 1000x higher than for Na + (6 mM). The transport stoichiometry is 1 glucose to 2 Na + or H +.

Structure

Proteins of the SSS vary in size from about 400 residues to about 700 residues and probably possess thirteen to fifteen putative transmembrane helical spanners (TMSs). They generally share a core of 13 TMSs, but different members of the family have different numbers of TMSs.

Transport Reaction

The generalized transport reaction usually catalyzed by the members of this family is:

Subfamilies

Proteins belonging to the SSS family can be found in the Transporter Classification Database .

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