What is SWISS-PROT in bioinformatics?
SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases.
How do you use SWISS-PROT?
SWISS-PROT provides detailed annotation information on protein sequences. Annotation include information on protein function, post-translational modification of proteins, domains and binding sites, secondary structures, quaternary structures, and diseases associated with protein deficiency.
What is the difference between SWISS-PROT and TrEMBL?
TrEMBL consists of entries in a SWISS-PROT format that are derived from the translation of all coding sequences in the EMBL nucleotide sequence database, that are not in SWISS-PROT. Unlike SWISS-PROT entries those in TrEMBL are awaiting manual annotation.
What are the differences between UniProtKB SWISS-PROT and UniProtKB TrEMBL?
UniProtKB/Swiss-Prot is manually curated which means that the information in each entry is annotated and reviewed by a curator, while the records in UniProtKB/TrEMBL are automatically generated and are enriched with automatic annotation and classification.
Is SWISS-PROT a secondary database?
Complete answer: SWISS PROT is a protein sequence database. Annotations in the database provide all the information regarding the structure and function of a particular protein along with its functions and modifications if any. The data is all primary and easily accessible.
When was SWISS-PROT established?
SWISS-PROT ( 1 ) is an annotated protein sequence database established in 1986 and maintained collaboratively, since 1987, by the Department of Medical Biochemistry of the University of Geneva and the EMBL Data Library (now the EMBL Outstation-The European Bioinformatics Institute; 2 ).
What is SWISS-PROT Wikipedia?
UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis.
Is SWISS-PROT UniProt?
Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. UniProtKB/Swiss-Prot is now the reviewed section of the UniProt Knowledgebase.
Is SWISS-PROT redundant?
- UniProtKB/Swiss-Prot is 'non-redundant' in the sense that all protein products encoded by one gene in a given species are represented in a single record. This includes alternative splicing isoforms, fragments, genetic variations, sequence conflicts, etc.
What is UniProtKB Swiss-Prot what is its purpose?
Its main goal is to provide the scientific community with a central resource for protein sequences and functional information. The UniProt consortium maintains the UniProt KnowledgeBase (UniProtKB) and several supplementary databases including the UniProt Reference Clusters (UniRef) and the UniProt Archive (UniParc).
Is Swiss-Prot manually annotated?
The Swiss-Prot section of the UniProt KnowledgeBase (UniProtKB/Swiss-Prot) contains publicly available expertly manually annotated protein sequences obtained from a broad spectrum of organisms.
What is UniProt used for?
UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.
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1. 10/18/2017 1 Swiss-Prot Protein Database Dr. Ayaz Ahmad What is Swiss-Prot? • Annotated sequence database established in 1986 • Consists of sequence entries of different line formats • Similar format to European Bioinformatics Institute Nucleotide Sequence Database (EMBL)
Swiss prot protein database
1. 10/18/2017 1 Swiss-Prot Protein Database Dr. Ayaz Ahmad What is Swiss-Prot? • Annotated sequence database established in 1986 • Consists of sequence entries of different line formats • Similar format to European Bioinformatics Institute Nucleotide Sequence Database (EMBL)