How do I access Swiss-Prot?
There are multiple sites on the Web that can access the Swiss-Prot/TrEMBL and retrieve the database. Its main sites are the ExPASy Molecular Biology website (http://www.expasy.org/) and the European Institute of Bioinformatics (EBI) website (http://www.ebi.ac.uk/swissprot/).
What is Swiss-Prot database?
SWISS-PROT (1) is an annotated protein sequence database, which was created at the Department of Medical Biochemistry of the University of Geneva and has been a collaborative effort of the Department and the European Molecular Biology Laboratory (EMBL), since 1987.
Is Swiss-Prot and UniProt same?
Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. UniProtKB/Swiss-Prot is now the reviewed section of the UniProt Knowledgebase.
How is Swiss-Prot different from TrEMBL?
TrEMBL consists of entries in a SWISS-PROT format that are derived from the translation of all coding sequences in the EMBL nucleotide sequence database, that are not in SWISS-PROT. Unlike SWISS-PROT entries those in TrEMBL are awaiting manual annotation.
Who created SWISS-PROT database?
SWISS-PROT ( 1 ) is an annotated protein sequence database established in 1986 and maintained collaboratively, since 1987, by the Department of Medical Biochemistry of the University of Geneva and the EMBL Data Library (now the EMBL Outstation-The European Bioinformatics Institute; 2 ).
What is SWISS-PROT Wikipedia?
UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis.
Is Swiss-Prot a primary database?
SWISS PROT is a protein sequence database. Annotations in the database provide all the information regarding the structure and function of a particular protein along with its functions and modifications if any. The data is all primary and easily accessible.
Is Swiss-Prot manually annotated?
The Swiss-Prot section of the UniProt KnowledgeBase (UniProtKB/Swiss-Prot) contains publicly available expertly manually annotated protein sequences obtained from a broad spectrum of organisms.
What is UniProt used for?
UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.
Which is the best annotated database?
Among all protein sequence databases, UniProt (UniProt Consortium, 2011) is the most widely used one. It provides more annotations than any other sequence database with a minimal level of redundancy through human input or integration with other databases.
Who created first bioinformatics database?
DayhoffJust a year later, Dayhoff gathered all the available sequence data to create the first bioinformatic database. The Protein Data Bank followed in 1972 with a collection of ten X-ray crystallographic protein structures, and the SWISSPROT protein sequence database began in 1987.
What is a TrEMBL?
1 : to shake involuntarily (as with fear or cold) : shiver. 2 : to move, sound, pass, or come to pass as if shaken or tremulous the building trembled from the blast. 3 : to be affected with great fear or anxiety trembled for the safety of her child.
URICHECK Glucose, pH, Protein
Abstract Glucose-galactose binding protein (GGBP) is used as an optical biosensor in bioprocess and medical applications. This article investigates the effect of pH on the behaviour of Acrylodan-labeled GGBP-L255C in …
HLAaccu Test
Genotyping of HLA-A or HLA-B HLA-A and HLA-B (major histocompatibility complex, class I, A, and B) are closely related proteins in the human leukocyte antigen (HLA) complex. They play important …
Assay Protocols Validated On
Validation methods are completed to ensure that an analytical methodology is accurate, specific, reproducible and resistant in the specified range in which a target analyte will be analyzed. Assay validation …
Total Antioxidant Status (TAS)
Abstract Introduction: Laparoscopic cholecystectomy is the gold standard for the treatment of gallstone disease; however, adverse hemodynamic changes induced by increased intra-abdominal pressure due to pneumoperitoneum are known to occur. …
Amyloid β-protein is neurotrophic and neurotoxic
The composition of these swimming swimming pools of Aβ shows utterly totally different populations of amyloid deposits, and has explicit correlates with the scientific standing of the affected particular person. …
acrylamide and methylene bisacrylamide Accu Gels
Dependable AccuGel 29:1 is a stabilized, ready-to-use resolution of 40% (w/v) acrylamide : bisacrylamide (29:1). AccuGel 29:1 has zero acrylic acid content material, eliminating the mounted expenses that trigger band streaking. …
Concanavalin A from Canavalia ensiformis
Uncover the Correct Stain for Your Utility Con A and completely different lectins are carbohydrate binding proteins that acknowledge specific sugar moieties on glycoproteins. The presence and distribution of these …
Proteins
SWISS-PROT (Bairoch and Apweiler, 1996) is an annotated protein sequence database established in 1986 and maintained collaboratively, since 1987, by the Department of Medical Biochemistry of the University of Geneva and the EMBL Data Library.
From molecules to patients: the clinical applications of biological databases and electronic health records
Ayyagari Ramlal, ... Rubina Chongtham, in Translational Bioinformatics in Healthcare and Medicine, 2021
IFNα and IFNω
Katherine A. Fitzgerald, ... Robin E. Callard, in The Cytokine FactsBook and Webfacts (Second Edition), 2001
SWISS-MODEL
is a fully automated protein structure homology-modelling server, accessible via the Expasy web server, or from the program DeepView (Swiss Pdb-Viewer).
Repository
Every week we model all the sequences for thirteen core species based on the latest UniProtKB proteome. Is your protein already modelled and up to date in SWISS-MODEL Repository ?
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2, is a positive-sense, single-stranded RNA coronavirus. It is a contagious virus that causes coronavirus disease 2019 (COVID-19).
Focus on The group's Mission
- The Swiss-Prot team excels in the art of generating machine-readable knowledge of biology from the ever growing body of scientific publications. It is harnessing the power of deep learning to accelerate literature triage and information extraction, thus delivering the most accurate and informative evidence to users in a timely manner.
Biocuration and Software Development
- Our team of biocurators and software developers annotate, maintain and develop a range of internationally renowned expert-curated knowledge resources: 1. Two ELIXIR Core Data Resources: UniProtKB/Swiss-Prot protein sequence database, the most widely used protein information resource in the world, and the Rheadatabase of biochemical reactions 2. The HAMA…
Supporting Ai with machine-readable Biological Knowledge
- Knowledgebases like UniProtKB are an essential part of the AI ecosystem; the collective biological knowledge they contain, in the form of pathways, ontologies and networks, can be used to create generalizable and interpretable models that reveal actionable biological mechanisms. Find out more about the Group’s activities