sucralfate drug class

Precautions

Therapeutic class. This type of categorisation of drugs is from a medical perspective and categorises them by the pathology they are used to treat. Drug classes that are defined by their therapeutic use (the pathology they are intended to treat) include: Analgesics. Antibiotic. Click to read full answer.

What is the therapeutic classification of drugs?

The schedule of drugs refers primarily to a drug’s accepted medical use and the likelihood that a drug will cause a person to develop a substance use disorder. Drugs are also classified by their chemical makeup and the way they interact with the brain and body.

What is a scheduled drug classification?

Xyzal (levocetirizine) is an antihistamine. It blocks the action of histamine, a chemical that causes sneezing, itching, and other allergy symptoms. What is Xyzal (levocetirizine) used for? Seasonal allergies for people over 2 years old

What classification drug is Xyzal?

Hallucinogens are a class of drugs that cause hallucinations—profound distortions in a person’s perceptions of reality. Hallucinogens can be found in some plants and mushrooms (or their extracts) or can be man-made, and they are commonly divided into two broad categories: classic hallucinogens (such as LSD) and dissociative drugs (such as PCP).

What is the drug classification of hallucinogenic?

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Is sucralfate a PPI?

Carafate and omeprazole belong to different drug classes. Carafate is an anti-ulcer drug and omeprazole is a proton pump inhibitor (PPI). Side effects of Carafate and omeprazole that are similar include headache, dizziness, diarrhea, nausea, and vomiting.

Is sucralfate an H2 blocker?

Gastric Ulcer Studies have shown that sucralfate is as effective as H2 receptor antagonists, with an average ulcer healing rate of 88% in 8 weeks. Because sucralfate is only minimally absorbed, it has an excellent safety profile; the most common side-effect is constipation.

What class of medication is Carafate?

Carafate belongs to a class of drugs called Gastrointestinal Agents, Other. It is not known if Carafate is safe and effective in children.

What is the medication sucralfate used for?

Sucralfate is used to treat and prevent duodenal ulcers and other conditions as determined by your doctor. It works by forming a barrier or coat over the ulcer. This protects the ulcer from the acid of the stomach, allowing it to heal. Sucralfate contains an aluminum salt.01-Feb-2022

What is a good substitute for sucralfate?

Nexium.Protonix.Famotidine.Prilosec.Dexilant.Prilosec OTC.

Does sucralfate help bile reflux?

Sucralfate. This medication can form a protective coating that protects the lining of the stomach and esophagus against bile reflux. Bile acid sequestrants. Doctors often prescribe bile acid sequestrants, which disrupt the circulation of bile, but studies show that these drugs are less effective than other treatments.06-Jan-2022

Does sucralfate relieve pain?

Sucralfate administration was accompanied by the disappearance of heartburn, epigastric pain, epigastric distress, or epigastric burning in 42 of 59 occurrences, and by statistically significant reductions in bloating. There was a trend toward significance in decreased nocturnal abdominal pain and in belching.

What is the most common side effect of sucralfate?

The most common side effect of sucralfate is constipation. The medication works by binding to ulcers to protect them from further exposure to stomach acid, bile, pepsin, and bile salts. This gives the ulcers time to heal.27-Oct-2021

Is sucralfate and Carafate the same medicine?

Sucralfate, also called Carafate, is a prescription medication used to treat duodenal ulcers, which form in the first part of the small intestine. Duodenal ulcers are a type of peptic ulcer.16-Nov-2021

Can you take sucralfate and omeprazole together?

If you are also taking sucralfate, take omeprazole at least 30 minutes before sucralfate. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue to take this medication for the prescribed length of treatment even if you are feeling better.

Does sucralfate heal gastritis?

Sucralfate is the primary agent for prophylaxis of stress gastritis. It has long been used as a means of decreasing the incidence of gastritis. This drug is readily available, easy to administer, and inexpensive.14-Apr-2020

How quickly does sucralfate work?

It takes about 2 weeks for the full effect of the medication, so be patient!

Before Taking This Medicine

You should not use sucralfate if you are allergic to it.To make sure sucralfate is safe for you, tell your doctor if you have: 1. diabetes; 2. kidn...

How Should I Take Sucralfate?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.Take sucral...

What Happens If I Miss A Dose?

Take the missed dose as soon as you remember, but avoid taking any other medications within 2 hours before or after you take sucralfate. Skip the m...

What Should I Avoid While Taking Sucralfate?

Avoid taking any other medications within 2 hours before or after you take sucralfate. Sucralfate can make it harder for your body to absorb other...

Sucralfate Dosing Information

Usual Adult Dose for Duodenal Ulcer:1 g orally 4 times a day-Duration of therapy: 4 to 8 weeksComments:-Each dose should be taken on an empty stoma...

What Other Drugs Will Affect Sucralfate?

Sucralfate can make it harder for your body to absorb other medications you take by mouth. Avoid taking any other medications within 2 hours before...

Uses of Sucralfate Tablets

1. It is used to treat GI (gastrointestinal) ulcers. 2. It may be given to you for other reasons. Talk with the doctor.

What Do I Need to Tell My Doctor Before I Take Sucralfate Tablets?

1. If you have an allergy to sucralfate or any other part of this medicine (sucralfate tablets). 2. If you are allergic to any drugs like this one,...

What Are Some Things I Need to Know Or Do While I Take Sucralfate Tablets?

1. Tell all of your health care providers that you take this medicine (sucralfate tablets). This includes your doctors, nurses, pharmacists, and de...

How Is This Medicine (Sucralfate Tablets) Best Taken?

Use this medicine (sucralfate tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. Take on an...

What Are Some Side Effects That I Need to Call My Doctor About Right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...

What Are Some Other Side Effects of Sucralfate Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...

How Do I Store and/or Throw Out Sucralfate Tablets?

1. Store at room temperature. 2. Store in a dry place. Do not store in a bathroom. 3. Keep all drugs in a safe place. Keep all drugs out of the rea...

What is sucralfate used for?

Sucralfate is used to treat and prevent the return of duodenal ulcers ( ulcers located in first part of the small intestine). Treatment with other medications, such as antibiotics, may also be necessary to treat and prevent the return of ulcers caused by a certain type of bacteria (H. pylori) Sucralfate is in a class of medications called ...

How often should I take sucralfate?

Sucralfate comes as a tablet and liquid to take by mouth. If you are taking sucralfate to treat ulcers, the tablets or liquid usually are taken four times a day. If you are taking sucralfate to prevent an ulcer from returning after it has healed), the tablets usually are taken twice a day.

How long does sucralfate take to heal?

Shake the liquid well before each use to mix the medication evenly. This medicine must be taken regularly to be effective. It may take up to 8 weeks for ulcers to heal.

How long before sucralfate should I take antacids?

if you are taking antacids, take them at least 30 minutes before or after sucralfate. tell your doctor if you have or have ever had kidney disease, diabetes, or any conditions that may cause difficulty swallowing or that may affect your gag or cough reflexes.

What to do if you are allergic to sucralfate?

tell your doctor and pharmacist if you are allergic to sucralfate, any other medications, or any of the ingredients in sucralfate tablets or liquid. Ask your pharmacist for a list of the ingredients.

Can sucralfate cause constipation?

constipation. Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: hives. rash. itching. difficulty breathing or swallowing. swelling of the face, throat, tongue, or lips. Sucralfate may cause other side effects.

Can you flush sucralfate down the toilet?

Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze sucralfate liquid. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet.

How long does sucralfate last?

Sucralfate is indicated in: 1 Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with Sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination. 2 Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.

Can you overdose on sucralfate?

Due to limited experience in humans with overdosage of Sucralfate, no specific treatment recommendations can be given. Acute oral toxicity studies in animals, however, using doses up to 12 g/kg body weight, could not find a lethal dose. Sucralfate is only minimally absorbed from the gastrointestinal tract. Risks associated with acute overdosage should, therefore, be minimal. In rare reports describing Sucralfate overdose, most patients remained asymptomatic. Those few reports where adverse events were described included symptoms of dyspepsia, abdominal pain, nausea, and vomiting.

Does sucralfate reduce absorption?

Some studies have shown that simultaneous Sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline.

Does sucralfate cause aluminum in urine?

Concomitant use of Sucralfate with other products that contain aluminum, such as aluminum-containing antacids, may increase the total body burden of aluminum. Patients with normal renal function receiving the recommended doses of Sucralfate and aluminum-conta ining products adequately excrete aluminum in the urine. Patients with chronic renal failure or those receiving dialysis have impaired excretion of absorbed aluminum. In addition, aluminum does not cross dialysis membranes because it is bound to albumin and transferrin plasma proteins. Aluminum accumulation and toxicity (aluminum osteodystrophy, osteomalacia, encephalopathy) have been described in patients with renal impairment. Sucralfate should be used with caution in patients with chronic renal failure.

Does sucralfate help with duodenal ulcers?

Although the mechanism of Sucralfate’s ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action.

Is sucralfate excreted in milk?

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Sucralfate is administered to a nursing woman.

Does sucralfate absorb bile?

In vitro, Sucralfate adsorbs bile salts. These observations suggest that Sucralfate’s antiulcer activity is the result of formation of an ulcer-adherent complex that covers the ulcer site and protects it against further attack by acid, pepsin, and bile salts.

How long before taking sucralfate can you take antacids?

Follow all instructions closely. Take on an empty stomach. Do not take antacids 30 minutes before or after taking this medicine (sucralfate tablets). Try to space other drugs from this one by 2 hours. This medicine stops many drugs from getting into the body.

Can you take Sucralfate if you are 65?

If you are 65 or older, use this medicine (sucralfate tablets) with care. You could have more side effects. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

Can you share Sucralfate with others?

Do not share your drugs with others and do not take anyone else's drugs. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (sucralfate tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.

Can you take sucralfate with all your medications?

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (sucralfate tablets) with all of your drugs and health problems.

How long does sucralfate last?

Sucralfate is indicated for short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by X-ray or endoscopic examination. Sucralfate is also indicated for maintenance therapy ...

Is sucralfate safe for lactation?

Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk. Sucralfate is probably safe for use during lactation because the drug is minimally absorbed; it is unknown whether sucralfate is excreted in breast milk.

Is sucralfate a maintenance medication?

Sucralfate is also indicated for maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers . Sucralfate is available under the following different brand names: Carafate. Dosages of Sucralfate: Dosage Forms and Strengths. Tablet.

Can you take sucralfate with diabetes?

High blood sugar (hyperglycemia) has been reported when drug is used in patients with diabetes. Sucralfate may alter absorption of some drugs; take other medications 2 hours before taking sucralfate.

How to take sucralfate?

Take sucralfate on an empty stomach. Shake the oral liquid well before each use. Measure each dose with a marked measuring spoon, oral syringe, or medicine cup.

How does sucralfate work?

Sucralfate is used to treat and prevent duodenal ulcers and other conditions as determined by your doctor. It works by forming a barrier or coat over the ulcer. This protects the ulcer from the acid of the stomach, allowing it to heal. Sucralfate contains an aluminum salt.

What to do if you miss a sucralfate dose?

If you miss a dose of sucralfate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

How long does it take to take a gram of sulfate?

Adults—One gram (g) (10 milliliters [mL]) four times a day, taken on an empty stomach for 4 to 8 weeks.

Can you take sucralfate with Digoxin?

Using sucralfate with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Bictegravir. Digoxin. Dolutegravir. Elvitegravir. Ketoconazole. Raltegravir.

Can sucralfate be given to elderly?

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sucralfate in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving sucralfate.

Does sucralfate affect blood sugar?

It is very important that your doctor check your progress at regular visits to make sure that sucralfate is working properly and to check for unwanted effects. Sucralfate may affect your blood sugar levels .

Product (s) containing sucralfate

Brand names: Carafate Drug class (es): miscellaneous GI agents Sucralfate systemic is used in the treatment of:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

What is sucralfate used for?

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers Label, gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia 2. It is considered a cytoprotective agent, protecting cells in ...

Which drug decreases the excretion rate of sucralfate?

Hydroxocobalamin may decrease the excretion rate of Sucralfate which could result in a higher serum level. Hydroxyethyl Starch. Sucralfate may decrease the excretion rate of Hydroxyethyl Starch which could result in a higher serum level. Ibuprofen.

Is sucralfate good for GERD?

Sucralfate is also used in the prevention and/or treatment of gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia 2, 13. With our commercial data, access important information on dangerous risks, contraindications, and adverse effects.

Does pegylated sucralfate increase serum levels?

Antihemophilic factor (recombinant), PEGylated. Sucralfate may decrease the excretion rate of Anti hemophilic factor (recombinant), PEGylated which could result in a higher serum level. Antipyrine. Antipyrine may decrease the excretion rate of Sucralfate which could result in a higher serum level.

Can sucralfate cause constipation?

It is likely that overdose of sucralfate in humans would result in constipation, and supportive treatment would be advised 13. Use in pregnancy. This drug is considered a pregnancy Category B drug. Studies have been performed in rodents and rabbits at doses up to 50 times the recommended human dose.

Does sucralfate increase growth factors?

In addition, sucralfate acts to increase levels of growth factors locally, and also causes an increase in prostaglandins which are important in the healing of the mucosa (lining) of the gastrointestinal tract 2. Mechanism of action.

Is sucralfate a safe drug?

Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms. It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form 11, 12. Type.

What is sucralfate suspension?

Sucralfate suspension is recommended by the US-based National Capital Poison Center (Poison Control) as an intervention for known or suspected button battery ingestions to reduce the risk and severity of injury to the esophagus prior to the battery's endoscopic removal.

When was sucralfate approved?

Sucralfate was approved for medical use in the United States in 1981. It is available as a generic medication. In 2017, it was the 218th most commonly prescribed medication in the United States, with more than two million prescriptions.

How long does sucralfate act as a buffer?

Sucralfate is a locally acting substance that in an acidic environment (pH < 4) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose.

Is sucralfate used for peptic ulcers?

The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer prevention. Sucralfate has also been used for the following conditions: Active duodenal ulcer not related to NSAID use. Maintenance therapy for resolved duodenal ulcers.

Does sucralfate affect pH?

Sucralfate may be considered to have the advantage over H2-blockers and PPIs in this regard because sucralfate does not change the pH of gastric fluid. A majority of meta-analyses found that sucralfate therapy decreased the incidence of ventilator-associated pneumonia compared to H2-antagonists.

Does sucralfate help with stricture?

Prevention of stricture formation—Sucralfate has an inhibitory effect on stricture formation in experimental corrosive burns and can be used in the treatment of corrosive esophageal burns to enhance mucosal healing and suppress stricture formation. Proctitis from ulcerative colitis.

Is sucralfate safe for kidney failure?

The most common side effect seen is constipation (2-3%). Less commonly reported side effects (<0.5%) include flatulence, headache, hypophosphatemia, xerostomia (dry mouth), and bezoar formation. Use of this drug is not recommended for people with chronic kidney failure, as it might cause aluminium accumulation and toxicity . A few well-controlled studies have been carried out investigating the safety and efficacy of sucralfate in children and pregnant women ( Pregnancy Category B).

How does sucralfate work?

Sucralfate is used to treat and prevent duodenal ulcers and other conditions as determined by your doctor. It works by forming a barrier or coat over the ulcer. This protects the ulcer from the acid of the stomach, allowing it to heal. Sucralfate contains an aluminum salt.

Can you stop sucralfate?

Your provider will monitor the healing process and make adjustments to your dose. Don't stop taking sucralfate (Carafate) without consulting with your healthcare provider as it may impact the ulcer healing process.

Can sucralfate be used in elderly?

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sucralfate in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

Does carafate cause seizures?

Low levels of aluminum are not a problem, but higher levels can be. High aluminum levels can cause confusion, muscle weakness, bone pain and related problems, and more seriously, seizures.

Is sucralfate FDA approved?

Sucralfate (Carafate) is FDA-approved for the treatment and management of duodenal ulcers (ulcers that are located in the first part of the small intestine).

Sucralfate Description

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