- Chest tightness.
- clay-colored stools.
- difficulty with swallowing.
- fast heartbeat.
- hives, itching, or skin rash.
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.
- light-colored stools.
- stomach pain, continuing.
Should fluconazole be taken with food?
Take Fluconazole pill with or without food along with a full 8 oz. glass of water. Taking the medication with food and water helps prevent any nauseating sensation. Evenly space out the doses of the antibiotic and take the dose at the scheduled time every day.
Does fluconazole do any damage to the kidneys?
Increased side effects can include kidney damage. Your doctor will check your blood for signs of kidney damage while you’re taking fluconazole. If you show signs of kidney damage, your doctor may lower your doses of these drugs or stop them completely until your treatment with fluconazole is done. Theophylline.
Who should not take fluconazole?
You should not use fluconazole if you are allergic to it. Some medicines can cause unwanted or dangerous effects when used with fluconazole. Your doctor may change your treatment plan if you also use: an antibiotic, antifungal, or antiviral medicine; a blood thinner; cancer medicine; cholesterol medication;
Can you drink alcohol while taking fluconazole?
Drinking alcohol while taking fluconazole is not contraindicated as they do not have any direct drug interactions. However, alcohol should be used in moderation or with caution while taking fluconazole as it has the potential to increase the risk of gastrointestinal side effects.
See more
What should I avoid while taking fluconazole?
Common medications that may interact with fluconazole include: anticoagulants or antiplatelet agents (blood thinners), such as warfarin, clopidogrel, (may prolong bleeding time) biologics, such as acalabrutinib, bosutinib, or entrectinib. albuterol.
How do you feel after taking fluconazole?
by Drugs.com A skin rash or itching is a common side effect of Fluconazole. You do not need to be concerned unless you start feeling symptoms of an allergic reaction: swelling of your face, lips, tongue, or throat, hives or difficulty breathing; in which case you should get to an emergency department immediately.
How do I know if fluconazole is working?
Fluconazole 150 mg capsules are an antifungal medication used to treat vaginal yeast infections caused by the yeast known as Candida. It works by stopping the growth of Candida. It usually starts to work within one day, but it may take 3 days for your symptoms to improve and up to 7 days for your symptoms to disappear.
What are the long term effects of fluconazole?
In our experience, long-term courses of fluconazole therapy are associated with frequent adverse effects. These range from the relatively benign, such as nausea, to severe and life-threatening hepatitis.
Does fluconazole make you tired?
Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally.
Does fluconazole push the yeast out?
Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast (fungus).
Is one fluconazole pill enough?
Fluconazole (Diflucan) is a popular yeast infection medication that only requires one dose. However, yeast infection pills require a prescription and are not available over-the-counter (OTC).
How long does it take for a yeast infection to go away with fluconazole?
If you have vaginal thrush, balanitis or oral thrush, your symptoms should be better within 7 days of taking fluconazole. If you have a serious fungal infection, ask your doctor how long it will take for fluconazole to start to work. It may be 1 to 2 weeks before it reaches its full effect.
Why am I still itching after taking fluconazole?
— Most yeast infections go away within a few days of starting treatment. However, you may continue to feel itchy and irritated, even after the infection is gone. If you do not get better within a few days after finishing treatment, call your doctor or nurse for advice.
Does fluconazole cause anxiety?
The commonest side effects were dry skin (xerosis), hair loss (alopecia) and fatigue. Other side effects included nausea and vomiting, loss of appetite, headache, joint discomfort, dry lips, dry mouth and loss of taste, dizziness or low blood pressure, neuropathy, impotence, anxiety, and brittle nails.
What does fluconazole do to the liver?
The severity of liver injury from fluconazole ranges from mild and transient enzyme elevations to clinically apparent hepatitis to acute liver failure and death. Most patients recover with stopping fluconazole, but resolution may be slow requiring 3 to 4 months. Rechallenge may lead to recurrence and should be avoided.
Before Taking This Medicine
You should not use fluconazole if you are allergic to it.Some medicines can cause unwanted or dangerous effects when used with fluconazole. Your do...
How Should I Take Fluconazole?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.Your do...
What Happens If I Miss A Dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include confusion or unusual thoughts or beh...
What Should I Avoid While Taking Fluconazole?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.Avoid driving or hazardous activity until you know how thi...
What Other Drugs Will Affect Fluconazole?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may in...
What are the side effects of fluconazole?
Check with your doctor immediately if any of the following side effects occur while taking fluconazole: Rare. Chills. clay-colored stools. cough.
What are the symptoms of overdose on fluconazole?
Get emergency help immediately if any of the following symptoms of overdose occur while taking fluconazole: Symptoms of overdose. Fearfulness, suspiciousness, or other mental changes. seeing, hearing, or feeling things that are not there.
What are the symptoms of a syringe?
hoarseness. increased thirst. irregular or slow heart rate. joint or muscle pain. loss of bladder control. lower back or side pain. mood changes. muscle pain or cramps. muscle spasm or jerking of the arms and legs.
Can you have seizures after 100 mg?
Rare cases of seizures have been reported, but a causal relationship was difficult to establish, since some of these patients had cryptococcal meningitis or severe underlying disease. Nonetheless, at least 1 case of seizure following a 100 mg oral dose has been reported .
Does fluconazole need immediate medical attention?
Side effects not requiring immediate medical attention. Some side effects of fluconazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
If experienced, these tend to have a Severe expression i
Sorry, we have no data available. Please contact your doctor or pharmacist.
Are you currently using fluconazole?
This survey is being conducted by the WebMD marketing sciences department.
How to take fluconazole?
Fluconazole oral is taken by mouth. Fluconazole injection is given as an infusion into a vein. You may take fluconazole oral with or without food. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
What is fluconazole used for?
Fluconazole is an antifungal medicine that is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood. Fluconazole is also used to prevent fungal infection in people who have a weak immune system caused by cancer treatment, ...
Why is fluconazole used for meningitis?
Fluconazole is also used to prevent fungal infection in people who have a weak immune system caused by cancer treatment, bone marrow transplant, or diseases such as AIDS. Fluconazole is also used to treat a certain type of meningitis in people with HIV or AIDS.
What are the side effects of a syringe?
Common side effects may include: nausea, stomach pain, diarrhea, upset stomach; headache; dizziness; or. changes in your sense of taste. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Can fluconazole harm a baby?
Talk to your doctor before using this form of fluconazole if you have a problem digesting sugars or milk. Fluconazole may harm an unborn baby. Use effective birth control to prevent pregnancy while taking fluconazole and for at least 1 week after your last dose.
Can you take fluconazole and other medications at the same time?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Fluconazole can cause a serious heart problem.
Does fluconazole cause hives?
Fluconazole side effects. Get emergency medical help if you have signs of an allergic reaction ( hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
What is diflucan used for?
Diflucan is also used to treat cryptococcal meningitis, and prevention of Candida infections in patients treated with chemotherapy or radiation after bone marrow transplantation. Diflucan prevents growth of fungi by preventing production of the membranes that surround fungal cells. Common side effects of Diflucan include.
Does Diflucan cause angioedema?
Stevens-Johnson syndrome. Rarely, serious allergic reactions, including angioedema ( swelling of tissues ), may also occur . Drug interactions of Diflucan include hydrochlorothiazide, which increases the blood concentration of Diflucan by 40%.
Can you take diflucan while pregnant?
Use of Diflucan during pregnancy is not recommended. Diflucan is secreted in breast milk at concentrations similar to the mother's blood level. However, Diflucan is used for treating neonates with fungal infections and for treating lactation associated Candida infections.
Is diflucan good for a pregnant woman?
Use of Diflucan during pregnancy is not recommended. Available evidence suggests that use of Diflucan during breastfeeding has little risk.
Does fluconazole increase AUC?
Fluconazole increases the AUC of triazolam (single dose) by approximately 50%, Cmax by 20% to 32%, and increases t ½ by 25% to 50 % due to the inhibition of metabolism of triazolam.
Does diflucan increase terfenadine levels?
Another study at a 400 mg and 800 mg daily dose of fluconazole demonstrated that Diflucan taken in doses of 400 mg/day or greater significantly increases plasma levels of terfenadine when taken concomitantly. The combined use of fluconazole at doses of 400 mg or greater with terfenadine is contraindicated.
Is Fluconazole a calcium channel blocker?
Certain calcium channel antagonists ( nifedipine, isradipine, amlodipine, verapamil, and felodipine) are metabolized by CYP3A4. Fluconazole has the potential to increase the systemic exposure of the calcium channel antagonists. Frequent monitoring for adverse events is recommended.
How many milligrams of fluconazole are there?
The warning and class change came on the heels of a study that uncovered the disturbing fact that doses between 400 and 800 milligrams of fluconazole cause specific birth defects when women use the drug at these doses over the long-term during pregnancy.
When did the FDA start warning about fluconazole?
The first official warning only came in 2011 from the FDA when the agency upgraded the pregnancy class of higher doses of fluconazole from C to D, a classification that communicates this drug is known to cause harm to human fetuses.
What class of antifungal is fluconazole?
Fluconazole belongs to the triazole class of antifungal medications. These drugs treat and cure fungal infections by acting on an enzyme on fungal cells. The result is that it slows the growth of the fungus and slows and stops the spread of the infection. The FDA approved fluconazole to treat a number of fungal infections, ...
Where does fluconazole come from?
Fluconazole Uses. Fluconazole came from Pfizer, the major drug maker that developed it in the 1980s and received U.S. Food and Drug Administration (FDA) approval in 1990. Pfizer marketed and sold the drug as Diflucan. Since 1990 the patent has run out and while Pfizer still offers Diflucan, other companies have also gotten in on making ...
Can fluconazole be given to AIDS patients?
Patients with cancer or AIDS who are vulnerable to developing fungal infections may be given fluconazole to prevent fungal infections. In fewer cases the drug may be used to treat skin, eye and prostate fungal infections.
Does fluconazole cause miscarriages?
As if all the previous side effects were not troubling enough, fluconazole has recently been found to cause birth defects and miscarriages. Since the drug came on the market in 1990 millions of women and their babies were exposed to this risk without warning. The first official warning only came in 2011 from the FDA when the agency upgraded the pregnancy class of higher doses of fluconazole from C to D, a classification that communicates this drug is known to cause harm to human fetuses.
Does fluconazole help with yeast infections?
The FDA approved fluconazole to treat a number of fungal infections, especially yeast infections. These include vaginal, abdominal, esophageal, lung, blood, and mouth yeast infections. The FDA also approved fluconazole to treat fungal meningitis, a fungal infection of the covering membrane of the spine and brain called the meninges.
What to tell your doctor before taking fluconazole?
Before using fluconazole, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heartproblems (heart failure, slow heartbeat, QT prolongation in the EKG), family historyof certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Can fungusto cause nausea?
Stopping the medication too early may allow the fungusto continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or if it worsens. Side Effects . Nausea, vomiting, diarrhea, stomachupset/pain, headache, dizziness, or hair lossmay occur.
Can fluconazole be taken in breast milk?
Discuss the risks and benefits with your doctor. Fluconazole passes into breastmilk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
Does fluconazole affect QT?
Many drugs besides fluconazolemay affect the heartrhythm (QT prolongation), including pimozide, quinidine, macrolide antibiotics(such as erythromycin), among others. Fluconazole can slow down the removal of other medications from your body, which can affect how they work.
Can fluconazole make you dizzy?
Talk to your doctor about using fluconazole safely. Although uncommon, this drug may make you dizzy. Alcohol or marijuana(cannabis) can make you more dizzy.
Can you take fluconazole if you are allergic to it?
Precautions . Before taking fluconazole, tell your doctor or pharmacistif you are allergic to it; or to other azole antifungaldrugs (such as ketoconazole, itraconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Can fluconazole cause QT prolongation?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease. Fluconazole may cause a condition that affects the heartrhythm (QT prolongation).
How does fluconazole work?
Fluconazole may be used to treat fungal infections. Fluconazole works by inhibiting an enzyme in fungi , called lanosterol 14-α-demethylase, responsible for the conversion of lanosterol, a type of fat, to ergosterol. This interferes with the formation of the fungal cell membrane.
What medications can interact with fluconazole?
Common medications that may interact with fluconazole include: anticoagulants or antiplatelet agents (blood thinners), such as warfarin, clopidogrel, (may prolong bleeding time) biologics, such as acalabrutinib, bosutinib, or entrectinib. albuterol. antibiotics, such as ciprofloxacin, erythromycin, or moxifloxacin.
How long does it take for fluconazole to stop working?
The enzyme inhibiting effect of fluconazole persists for 4 to 5 days after discontinuation of fluconazole. Although single-dose fluconazole is effective for vaginal yeast infections, there is a higher risk of adverse reactions (26%) versus intravaginal agents (16%).
How long does it take for fluconazole to abate?
6. Response and effectiveness. Peak levels of fluconazole are reached within one to two hours of oral administration. However, signs of infection may take longer to abate.
Does fluconazole help with infection?
However, signs of infection may take longer to abate. Fluconazole has a long half-life and single-dose therapy or once-daily dosing is usually sufficient for most infections. Fluconazole is rapidly and completely absorbed after oral administration.
Can fluconazole be used for kidney disease?
The dosage of fluconazole may need to be reduced in people with kidney disease ( does not apply to single-dose therapy). Caution should be exercised when administering fluconazole to people with liver disease. Rarely, serious, potentially fatal, liver damage may occur. The risk is higher in people with serious underlying diseases.
Can fluconazole cause dizziness?
Anaphylaxis and a rash have been reported rarely. In some people, fluconazole may cause dizziness and affect their ability to drive a car or operate machinery. Avoid alcohol.
in Summary
For The Consumer
Common side effects
- Headache disorder
- Nausea
- Allergic dermatitis
- Pruritus of skin
- Drowsy
Common side effects
- Headache disorder
- Nausea
- Allergic dermatitis
- Pruritus of skin
- Drowsy
- Dizziness
- Skin rash
- Anorexia
- Vomiting
- Diarrhea
- Acute abdominal pain
- Dyspepsia
If any of these effects persist or worsen, tell your doctor or pharmacist promptly
- Nausea
- Diarrhea
- Stomach pain
- Headache
- Dizziness
If any of these effects persist or worsen, tell your doctor or pharmacist promptly
- Nausea
- Diarrhea
- Stomach pain
- Headache
- Dizziness
Get medical help right away if any of these rare but serious side effects occur
- Fast/irregular heartbeat
- Severe dizziness
- Fainting
This drug may rarely cause serious liver disease. Get medical help right away if you develop any signs of liver disease, including
- Severe stomach/abdominal pain
- Persistent nausea/vomiting
- Yellowing eyes/skin
- Dark urine
- Unusual tiredness
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including
- Rash
- Itching/swelling
- Severe dizziness
- Trouble breathing
Other things to note
- If your doctor has directed you to use this product, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using the product do not have serious side effects.
Frequently Asked Questions
Further Information