Receiving Helpdesk

procheck tutorial

by Roselyn Parker Published 3 years ago Updated 2 years ago

What is a proplot script?

What is a coordinate file?

About this website

How do you run Procheck?

To run PROCHECK:Enter the 4-letter PDB code of the protein of interest, its chain ID (if required) and its resolution.Click on RUN to run the program.Click on Reset to enter new code.

What is Procheck in bioinformatics?

PROCHECK checks the stereochemical quality of a protein structure, producing a number of PostScript plots analysing its overall and residue-by-residue geometry. It includes PROCHECK-NMR for checking the quality of structures solved by NMR.14-Jan-2010

How do I install Procheck?

First, followed by instruction of Procheck official site, download all required file. (you need to fax the license agreement first). I use tar command to uncompress the procheck.19-Mar-2012

What is protein validation?

WHAT IF also provides an environment for: homology modeling of protein tertiary structures and quaternary structures; validating protein structures, notably those deposited in the PDB; correcting protein structures; visualising macromolecules and their interaction partners (for example, lipids, drugs, ions, and water), ...

How do you cite Pdbsum?

PDBsum is a database that provides an overview of the contents of each 3D macromolecular structure deposited in the Protein Data Bank....PDBsum.ContentAuthorsRoman Laskowski & al. (1997)Primary citationPMID 9433130AccessWebsitewww.ebi.ac.uk/pdbsum/8 more rows

What is Q mean score?

QMEAN, which stands for Qualitative Model Energy ANalysis, is a composite scoring function describing the major geometrical aspects of protein structures. Five different structural descriptors are used. The local geometry is analyzed by a new kind of torsion angle potential over three consecutive amino acids.

What is a good MolProbity score?

A value -4 < x < 2 is considered appropriate for normal structures. This pre-print provides more details: Link. Molprobity score: Combines all the geometric scores into a single value to suggest quality. Lower values and higher percentiles are better.31-Aug-2020

What is protein if Modelling?

Called WHAT IF, it provides an intelligent and flexible environment for displaying, manipulating, and analyzing small molecules, proteins, nucleic acids, and their interactions. A relational protein structure database is incorporated to be queried. The program is suitable for most common crystallographic work.

What is protein model validation tool?

ProTSAV is a meta-server, which has a collection of model quality assessment programs that evaluate the quality of a protein and correctness of the structural model. It predicts a global quality score for submitted input structure.

What is a proplot script?

The PROPLOT script runs just the plotting programs that generate the output PostScript files. It skips the programs that calculate the data, and so is much faster than running PROCHECK all over again. (Of course, the calculation programs need to have been run at least once so that all the required data files are present). The script is particularly useful if you want to regenerate some, or all, of the plots, perhaps with different plot parameters in the procheck.prm file (see Customizing the PROCHECK plots ).

What is a coordinate file?

coordinate_file is the name of the file containing your protein structure and should include the full path unless the file is in the default directory. The file must be in Brookhaven format (see Appendix B ).

Does ProCheck use custom calibration?

The PROCHECK can use custom calibration for certain sensor types. Custom calibrations apply directly to the raw analog-to-digital count (ADC) in the form of a fifth-order polynomial. For more information on creating a custom calibration, please refer to Soil-specific

Can you return a ProCheck to Meter?

The PROCHECK may be returned to METER for maintenance in the following areas: system inspection, parts replacement, and instrument cleaning. Replacement parts can also be ordered from METER. Contact Customer Support for more information.

Download

PROCHECK is available free. Download details are given here. We request that you complete and sign the Confidentiality Agreement (see below) and return by post, fax or e-mail (see Contact details ). Non-academic users can strike out Clause 7 of the agreement.

Notes

You can upload your structure to PDBsum to have a full set of PDBsum analyses, including PROCHECK plots, generated for it. (Use the Generate option in the left-hand menu).

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