ondansetron side effects

Does ondansetron cause weight gain?

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics. Zofran (ondansetron) comes in many different forms that you don't have to swallow, such as a film that goes on the tongue or a dissolving pill.

Does ondansetron make you high?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ondansetron. Taking ondansetron while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "serotonin syndrome," which can be fatal. Tell your doctor if you also use:

What are the contraindications of ondansetron?

You must not take Zofran Tablets if:

• You are taking apomorphine (used to treat Parkinson's disease);
• You have ever had an allergic reaction to ondansetron or any of the ingredients listed here;
• You are pregnant, trying to become pregnant or breastfeeding unless your doctor says it is safe;

Why would you take ondansetron?

The way you have been told to take it will depend upon the reason why you are taking it:

• If you are due to have a chemotherapy or radiotherapy treatment that could cause you to feel sick, your doctor will prescribe you a dose of ondansetron to take an ...
• If you are being prescribed ondansetron because you are due to have surgery, you will be given a dose to take shortly before the operation.
• Ondansetron can also be given by injection. ...

See more

What is a common side effect of ondansetron?

Zofran (ondansetron) is used to relieve nausea and vomiting commonly associated with cancer treatments like chemotherapy and radiation. It can also be used to prevent and treat post-surgical nausea and vomiting. Common side effects associated with Zofran include headache, drowsiness, constipation and the chills.

What happens when you take ondansetron?

Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting. Ondansetron is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment.

How long does it take for ondansetron to kick in?

You can take ondansetron with or without food. Ondansetron should start to work within 30 minutes to an hour. Ondansetron tablets are available in two different forms – tablets or oral disintegrating tablets (also called ODT). Tablets: swallow the tablets with a glass of water.

When should you not take Zofran?

You should not use Zofran if you are allergic to ondansetron or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi). Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

What can you not take with ondansetron?

Most frequently checked interactionsAspirin Low Strength (aspirin)Benadryl (diphenhydramine)Cymbalta (duloxetine)Fish Oil (omega-3 polyunsaturated fatty acids)Flonase (fluticasone nasal)Lyrica (pregabalin)Metoprolol Succinate ER (metoprolol)Metoprolol Tartrate (metoprolol)More items...

What is the strongest anti nausea medication?

One of the most effective anti-nausea medications is Zofran (ondansetron) which was developed to solve this problem. Zofran is available as tablets, dissolvable tablets, strips, or liquid. While it is safe for the general population, it is so effective, that it is also used in patients undergoing chemotherapy.

Can you take ondansetron on an empty stomach?

To prevent nausea after surgery, take ondansetron by mouth 1 hour before the start of surgery. This medication may be taken with or without food. However, your doctor may tell you not to eat before chemotherapy, radiation, or surgery.

Does ondansetron make you sleepy?

Ondansetron orally disintegrating tablet may cause drowsiness. It can also cause other side effects.

Is ondansetron used for anxiety?

Conclusions: Ondansetron has been shown to be an effective treatment for early-onset alcoholism. Ondansetron's ability to improve symptoms of depression, anxiety, and hostility among EOA may make an additional contribution to its therapeutic effect.

Why was Zofran taken off the market?

FDA Drug Safety Communications & Zofran Recall In 2012, the 32 mg intravenous dose of Zofran was pulled from the market due to concerns that it could trigger QT interval prolongation, a heart rhythm disorder that could lead to an abnormal and potentially fatal heart rhythm called Torsades de Pointes.

Does ondansetron raise blood pressure?

Conclusions: Ondansetron given intravenously attenuates the fall of systolic and mean blood pressure, but does not have an influence on diastolic blood pressure or heart rate.

Does Zofran affect the heart?

The FDA previously noted cardiovascular safety concerns that suggested Zofran (ondansetron) could cause QT prolongation, which can lead to a serious and sometimes fatal heart rhythm called Torsade de Pointes.

What are the side effects of a syringe?

pounding heartbeat. slow or irregular breathing. sticking out of the tongue. sweating. trouble with speaking. unconscious. uncontrolled twisting movements of the neck, trunk, arms, or legs. unusual facial expressions. Some side effects may occur that usually do not need medical attention.

Can medicine cause side effects?

Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:

What inducers increase ondansetron?

In patients treated with potent inducers of CYP3A4 (i.e., phenytoin, carbamazepine, and rifampin), the clearance of ondansetron was significantly increased and ondansetron blood concentrations were decreased.

What enzymes are involved in the metabolism of Ondansetron?

Because ondansetron is metabolized by hepatic cytochrome P450 drug-metabolizing enzymes (CYP3A4, CYP2D6, CYP1A2) , inducers or inhibitors of these enzymes may change the clearance and, hence, the half-life of ondansetron.

What is Zofran used for?

Zofran ( ondansetron) is an anti-nausea medication used to prevent and treat nausea and vomiting caused by cancer chemotherapy and to prevent vomiting and nausea after surgery. Chemotherapy agents cause increased secretion of serotonin, which stimulates serotonin (5-HT3) receptors in the brain, resulting in nausea and vomiting.

How does Zofran work?

Zofran works by selectively blocking serotonin (5-HT3) receptors, thereby reducing the effect of increased serotonin due to che motherapy. diarrhea. abnormal heart rate and rhythm. Drug interactions of Zofran include apomorphine, due to sudden lowering in blood pressure and loss of consciousness.

What are the adverse reactions to Zofran?

The most common adverse reactions (greater than or equal to 2%) reported in patients receiving Zofran and concurrent radiotherapy were similar to those reported in patients receiving Zofran and concurrent chemotherapy and were headache, constipation, and diarrhea.

What are the side effects of Zofran?

constipation, dizziness , and. diarrhea. Serious side effects of Zofran include. abnormal heart rate and rhythm. Drug interactions of Zofran include apomorphine, due to sudden lowering in blood pressure and loss of consciousness. Phenytoin, carbamazepine, and rifampin can increase Zofran elimination and decrease blood levels, ...

Does Zofran affect alfentanil?

Zofran does not alter the respiratory depressant effects produced by alfentanil or the degree of neuromuscular blockade produced by atracurium. Interactions with general or local anesthetics have not been studied.

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

Are you currently using ondansetron HCl?

This survey is being conducted by the WebMD marketing sciences department.

How it works

Ondansetron belongs to a class of drugs called antiemetics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Antiemetics are drugs that reduce nausea and vomiting.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Drugs you should not use with ondansetron

Do not take these drugs with ondansetron. Doing so can cause dangerous effects in your body. Examples of these drugs include:

Interactions that increase your risk of side effects from ondansetron

Taking ondansetron with certain medications raises your risk of side effects from ondansetron. This is because the amount of ondansetron in your body may be increased. Examples of these drugs include:

Interactions that can make ondansetron less effective

Taking these drugs with ondansetron can make ondansetron less effective. This is because the amount of ondansetron in your body may be decreased. Examples of these drugs include:

Allergy warning

Ondansetron can cause a severe allergic reaction. Symptoms can include:

Warnings for people with certain health conditions

For people with risk factors for heart arrhythmias: If you have conditions such as heart failure or congenital long QT syndrome, this drug may increase your risk of arrhythmias. Ask your doctor if you have risk factors for arrhythmias.

What to know before taking Ondansetron?

Before using ondansetron, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems ( QT prolongation in the EKG, sudden cardiac death).

How to take Ondansetron HCL?

How to use Ondansetron Hcl. To prevent nausea from chemotherapy, take this medication by mouth usually within 30 minutes before treatment begins. To prevent nausea from radiation treatment, take this medication by mouth 1 to 2 hours before the start of your treatment. To prevent nausea after surgery, take ondanse tron by mouth 1 hour before ...

What are the side effects of a syringe?

Inform your doctor if your condition does not improve or if it worsens. Side Effects. Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly.

Can you take Ondansetron if you are allergic to it?

Precautions. Before taking ondansetron, tell your doctor or pharmacist if you are allergic to it; or to other serotonin blockers (e.g., granisetron ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Can Ondansetron make you dizzy?

Talk to your doctor about using ondansetron safely. This drug may make you dizzy or drowsy. Alcohol or marijuana ( cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages.

Can Ondansetron cause heart problems?

Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

What Is Zofran ODT?

Zofran ODT (ondansetron) is an antiemetic drug that helps prevent nausea and vomiting. This prescription medication dissolves on the top of your tongue and works by preventing a chemical called serotonin from reaching certain cells in the brain.

What Is Zofran ODT Used For?

The Food and Drug Administration (FDA) has approved Zofran ODT to prevent: 1

What Are the Side Effects of Zofran ODT?

This is not a complete list of side effects, and others may occur. A medical professional can advise you on side effects. If you experience other effects, contact your pharmacist or a medical professional. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

Dosage: How Much Zofran ODT Should I Take?

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

Overdose: What Happens If I Take Too Much Zofran ODT?

Cases of accidental Zofran overdose in children have been reported. Their symptoms were consistent with serotonin syndrome.

Precautions

Check with your doctor if severe nausea and vomiting continue after leaving the hospital or cancer treatment center.

What Other Medications Interact With Zofran ODT?

When taken with Zofran ODT, several medications may increase your risk of developing serotonin syndrome. Along with Zofran ODT, if you are taking a medicine that increases serotonin levels in the body, your doctor may need to choose a different treatment or monitor you more closely.