Precautions
What is the quickest way to get rid of a stomach bug?
- Drink lots of fluids. Share on Pinterest.
- Try eating the BRAT diet. Share on Pinterest.
- Try acupressure to reduce nausea. Acupressure has been shown to be effective in treating some types of nausea.
- Get plenty of rest.
- Medicate with caution.
How long should Zofran take to work?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ondansetron. Taking ondansetron while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "serotonin syndrome," which can be fatal. Tell your doctor if you also use:
Does ondansetron make you high?
[75] investigated the efficacy of ondansetron in 20 patients with fibromyalgia ... the clinician's perspective Medical Outcomes Study—Sleep (MOS- Sleep) Sleep A 12-question survey measuring ...
Does ondansetron Make you Sleepy?
An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of over-the-counter (OTC) and prescription medications. ODTs differ from traditional tablets in that they are designed to be dissolved on the tongue rather than swallowed whole. The ODT
What does ODT stand for in drug?
What is the drug ondansetron ODT used for?
Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery.
How long does it take for ondansetron take to kick in?
You can take ondansetron with or without food. Ondansetron should start to work within 30 minutes to an hour. Ondansetron tablets are available in two different forms – tablets or oral disintegrating tablets (also called ODT). Tablets: swallow the tablets with a glass of water.
When should you take ondansetron?
Adults and children 12 years of age and older—At first, one 8-milligram (mg) film taken 30 minutes before starting cancer treatment. The second 8-mg film is taken 8 hours after the first dose. Then, one 8-mg film is taken two times a day (every 12 hours) for 1 to 2 days.
What is a side effect of ondansetron?
SIDE EFFECTS: Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Does ondansetron make you sleepy?
Ondansetron orally disintegrating tablet may cause drowsiness. It can also cause other side effects.
Can you take ondansetron on an empty stomach?
To prevent nausea after surgery, take ondansetron by mouth 1 hour before the start of surgery. This medication may be taken with or without food. However, your doctor may tell you not to eat before chemotherapy, radiation, or surgery.
Is ondansetron used for anxiety?
Conclusions: Ondansetron has been shown to be an effective treatment for early-onset alcoholism. Ondansetron's ability to improve symptoms of depression, anxiety, and hostility among EOA may make an additional contribution to its therapeutic effect.
Is ondansetron 4 mg a narcotic?
Is Zofran (ondansetron) a narcotic? No, Zofran (ondansetron) is not a narcotic, instead it belongs to a class of medication called 5-HT3 (serotonin) receptor antagonist.
What is the strongest anti-nausea medication?
One of the most effective anti-nausea medications is Zofran (ondansetron) which was developed to solve this problem. Zofran is available as tablets, dissolvable tablets, strips, or liquid. While it is safe for the general population, it is so effective, that it is also used in patients undergoing chemotherapy.
Why is ondansetron not over the counter?
Ondansetron is a prescription medication, which means you can't get it over the counter. It must be prescribed by a healthcare professional.
Does ondansetron lower blood pressure?
Conclusions: Ondansetron given intravenously attenuates the fall of systolic and mean blood pressure, but does not have an influence on diastolic blood pressure or heart rate.
How long does it take for a pill to digest on an empty stomach?
In general, it typically takes approximately 30 minutes for most medications to dissolve.
What Do I Need to Tell My Doctor Before I Take Ondansetron Orally Disintegrating Tablets?
1. If you have an allergy to ondansetron or any other part of this medicine (ondansetron orally disintegrating tablets). 2. If you are allergic to...
What Are Some Things I Need to Know Or Do While I Take Ondansetron Orally Disintegrating Tablets?
1. Tell all of your health care providers that you take this medicine (ondansetron orally disintegrating tablets). This includes your doctors, nurs...
How Is This Medicine (Ondansetron Orally Disintegrating Tablets) Best Taken?
Use this medicine (ondansetron orally disintegrating tablets) as ordered by your doctor. Read all information given to you. Follow all instructions...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Ondansetron Orally Disintegrating Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Ondansetron Orally Disintegrating Tablets?
1. Store at room temperature. 2. Store in a dry place. Do not store in a bathroom. 3. Protect from light. 4. Keep all drugs in a safe place. Keep a...
What to know before taking Ondansetron?
Before using ondansetron, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems ( QT prolongation in the EKG, sudden cardiac death).
Where to report side effects?
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions.
Can Ondansetron make you dizzy?
Talk to your doctor about using ondansetron safely. This drug may make you dizzy or drowsy. Alcohol or marijuana ( cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages.
Can Ondansetron cause allergic reactions?
Precautions. Before taking ondansetron, tell your doctor or pharmacist if you are allergic to it; or to other anti- nausea serotonin blockers (e.g., granisetron ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Can Ondansetron cause heart problems?
Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
How it works
Ondansetron belongs to a class of drugs called antiemetics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Antiemetics are drugs that reduce nausea and vomiting.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Drugs you should not use with ondansetron
Do not take these drugs with ondansetron. Doing so can cause dangerous effects in your body. Examples of these drugs include:
Interactions that increase your risk of side effects from ondansetron
Taking ondansetron with certain medications raises your risk of side effects from ondansetron. This is because the amount of ondansetron in your body may be increased. Examples of these drugs include:
Interactions that can make ondansetron less effective
Taking these drugs with ondansetron can make ondansetron less effective. This is because the amount of ondansetron in your body may be decreased. Examples of these drugs include:
Allergy warning
Ondansetron can cause a severe allergic reaction. Symptoms can include:
Warnings for people with certain health conditions
For people with risk factors for heart arrhythmias: If you have conditions such as heart failure or congenital long QT syndrome, this drug may increase your risk of arrhythmias. Ask your doctor if you have risk factors for arrhythmias.
What Is Zofran ODT?
Zofran ODT (ondansetron) is an antiemetic drug that helps prevent nausea and vomiting. This prescription medication dissolves on the top of your tongue and works by preventing a chemical called serotonin from reaching certain cells in the brain.
What Is Zofran ODT Used For?
The Food and Drug Administration (FDA) has approved Zofran ODT to prevent: 1
What Are the Side Effects of Zofran ODT?
This is not a complete list of side effects, and others may occur. A medical professional can advise you on side effects. If you experience other effects, contact your pharmacist or a medical professional. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.
Dosage: How Much Zofran ODT Should I Take?
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
Overdose: What Happens If I Take Too Much Zofran ODT?
Cases of accidental Zofran overdose in children have been reported. Their symptoms were consistent with serotonin syndrome.
Precautions
Check with your doctor if severe nausea and vomiting continue after leaving the hospital or cancer treatment center.
What Other Medications Interact With Zofran ODT?
When taken with Zofran ODT, several medications may increase your risk of developing serotonin syndrome. Along with Zofran ODT, if you are taking a medicine that increases serotonin levels in the body, your doctor may need to choose a different treatment or monitor you more closely.
What to do if you think you have an overdose?
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Can you take Ondansetron with any medication?
You must check to make sure that it is safe for you to take this medicine (ondansetron orally disintegrating tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
How to take Ondansetron?
Take the ondansetron regular tablet with a full glass of water. To take the orally disintegrating tablet (Zofran ODT): Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil. Do not push a tablet through the foil or you may damage the tablet.
What are the symptoms of Ondansetron?
Get emergency medical help if you have signs of an allergic reaction to ondansetron: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe constipation, stomach pain, or bloating;
How much IV nausea is recommended for a 12 year old?
Parenteral:#N#1 month to 12 years:#N#Less than 40 kg:#N#-Recommended dose: 0.1 mg/kg IV over 2 to 5 minutes immediately prior to/following anesthesia induction or postoperatively (nausea and/or vomiting occurring shortly after surgery)#N#40 kg and greater:#N#-Recommended dose: 4 mg IV over 2 to 5 minutes immediately prior to/following anesthesia induction or postoperatively (nausea and/or vomiting occurring shortly after surgery)#N#Use:#N#-Prevention of postoperative nausea and vomiting
How much cisplatin should I take for chemo?
Oral:#N#Highly Emetogenic Cancer Chemotherapy (HEC):#N#-Recommended dose: 24 mg orally 30 minutes before the start of single-day HEC (including cisplatin doses of 50 mg/m2 or greater )#N#Moderately Emetogenic Cancer Chemotherapy (MEC):#N#-Recommended dose: 8 mg orally twice a day, with the first dose administered 30 minutes before the start of chemotherapy and the subsequent dose 8 hours later; then 8 mg orally 2 times a day (every 12 hours) for 1 to 2 days after the completion of chemotherapy#N#Parenteral:#N#-Recommended dose: 0.15 mg/kg IV, with the first dose (infused over 15 minutes) 30 minutes before the start of emetogenic chemotherapy and subsequent doses given 4 and 8 hours after the first dose.#N#-Maximum dose: 16 mg per dose#N#Comments:#N#-Multi-day, single-dose administration of 24 mg orally for HEC has not been studied.#N#-The injection formulation should be diluted prior to IV administration.#N#Uses:#N#-Prevention of nausea and vomiting associated with HEC or MEC#N#-Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic chemotherapy
What are the side effects of Ondansetron?
Common ondansetron side effects may include: diarrhea or constipation; headache; drowsiness; or. tired feeling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Can Ondansetron cause heart problems?
Ondansetron can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS.
Can Ondansetron harm a baby?
Ondansetron is not expected to harm an unborn baby. Tell your doctor if you are pregnant. It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Ondansetron is not approved for use by anyone younger than 4 years old.
1. Indications and Usage Section
Ondansetron orally disintegrating tablets are indicated for the prevention of nausea and vomiting associated with:
2. Dosage and Administration Section
The recommended dosage regimens for adult and pediatric patients are described in Table 1 and Table 2, respectively. Corresponding doses of ondansetron tablets, ondansetron orally disintegrating tablets and ondansetron oral solution may be used interchangeably.
3. Dosage Forms and Strengths
Ondansetron Orally Disintegrating Tablets USP, 4 mg are white to off-white, round tablets debossed with ‘5’ on one side and ‘E’ on the other side with an embossed circular edge.
4. Contraindications
Ondansetron orally disintegrating tablets are contraindicated in patients:
7. Drug Interactions
Serotonin syndrome (including altered mental status, autonomic instability, and neuromuscular symptoms) has been described following the concomitant use of 5-HT3 receptor antagonists and other serotonergic drugs, including SSRIs and SNRIs. Monitor for the emergence of serotonin syndrome.
8. Use in Specific Populations
Published epidemiological studies on the association between ondansetron use and major birth defects have reported inconsistent findings and have important methodological limitations that preclude conclusions about the safety of ondansetron use in pregnancy (see Data).
9. Drug Abuse and Dependence
Animal studies have shown that ondansetron is not discriminated as a benzodiazepine nor does it substitute for benzodiazepines in direct addiction studies.
How to take Ondansetron?
1. Read the dosage directions on your prescription. Familiarize yourself with the appropriate dose of Ondansetron for you by reading your prescription. Depending upon the reason you are taking the medication, the dosage amount and frequency will vary.
What are the symptoms of Ondansetron?
Keep an eye out for symptoms of a potentially life-threatening allergic reaction called anaphylaxis after taking your Ondansetron. Wheezing, hives, swelling of the tongue and throat, and itchy skin are all symptoms to be taken seriously.
What is the ODT for nausea?
Ondansetron is a medication that helps control nausea and vomiting, and the ODT version simply stands for oral dissolving tablet. This rapid-melt formula makes it easy to control vomiting without having to drink extra liquid. By taking Ondansetron, you can get a break from your nausea and rest. Being aware of potential interactions ...
Can you stop taking Ondansetron?
Stop taking Ondansetron if severe vomiting or nausea persists . Call your doctor and stop taking your Ondansetron if the medication worsens or does not ease your nausea and vomiting. Though rare, it's possible that you may be having a negative reaction to the medication. [9]
Can you take Ondansetron with other medications?
Consult your doctor about whether other vitamins, supplements, and medications you take can be continued while taking Ondansetron. Ondansetron has the potential to interact with your other medications, altering their effects on you. [13]
Can Ondansetron cause anaphylactic reactions?
Anaphylactic reactions to Ondansetron are rare but possible. If you think you are experiencing a serious allergic reaction, go to your nearest emergency facility or call 911. Contact your doctor if you feel dizzy, faintness, or a racing heart. Tell your doctor about any history of heart arrhythmias in your family.
Is Ondansetron safe for breastfeeding?
Ondansetron is considered safe during pregnancy and breastfeeding. That said, always tell your doctor if you are pregnant or nursing so they can weigh the risks and benefits of your using Ondansetron. [14]#N#X Trustworthy Source Mayo Clinic Educational website from one of the world's leading hospitals Go to source
What is Zofran ODT used for?
Zofran ODT blocks the actions of chemicals in the body that can trigger nausea and vomiting. Zofran ODT is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment. Zofran ODT may be used for purposes not listed in this medication guide.
How to take Zofran ODT?
To take the orally disintegrating tablet (Zofran ODT): Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil. Do not push a tablet through the foil or you may damage the tablet. Use dry hands to remove the tablet and place it in your mouth.
What are the side effects of Zofran?
Zofran ODT side effects. Get emergency medical help if you have signs of an allergic reaction: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe constipation, stomach pain, or bloating; headache with chest pain and severe dizziness, fainting, ...
Can you take Zofran with breast milk?
It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Zofran ODT is not approved for use by anyone younger than 4 years old. Zofran ODTly disintegrating tablets may contain phenylalanine.
Is Zofran ODT safe?
you are allergic to Zofran ODT or similar medicines (dolasetron, granisetron, palonosetron ). To make sure Zofran ODT is safe for you, tell your doctor if you have: an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); a blockage in your digestive tract (stomach or intestines).
Can Zofran cause serotonin to be high?
Taking Zofran ODT while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "ser otonin syndrome," which can be fatal. Tell your doctor if you also use: medicine to treat depression; medicine to treat a psychiatric disorder;
How long does it take to take 8 mg of chemo?
Cancer Chemotherapy. 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose. Then administer 8 mg twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy. Radiotherapy.
How long after radiotherapy should I take 8 mg of a sulfate?
For single high-dose fraction radiotherapy to the abdomen: 8 mg administered 1 to 2 hours before radiotherapy, with subsequent 8-mg doses every 8 hours after the first dose for 1 to 2 days after completion of radiotherapy.
How long before radiotherapy to give 8 mg?
For daily fractionated radiotherapy to the abdomen: 8 mg administered 1 to 2 hours before radiotherapy, with subsequent 8-mg doses every 8 hours after the first dose for each day radiotherapy is given. Postoperative. 16 mg administered 1 hour before induction of anesthesia.
How long before chemo can you take cisplatin?
Cancer Chemotherapy. A single 24-mg dose administered 30 minutes before the start of single-day highly emetogenic chemotherapy, including cisplatin greater than or equal to 50 mg/m 2. Moderately Emetogenic. Cancer Chemotherapy. 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose.