Precautions
Low blood sugar may happen if you:
- take too much of some types of diabetes medicines
- eat meals irregularly or skip meals
- are fasting
- don't eat a healthy diet and aren't getting enough nutrients
- change what you eat
- increase your physical activity without eating more to compensate
- drink alcohol, especially after skipping a meal
- take some other medicines or herbal medicines at the same time
When should I take glimepiride 1 mg?
To make sure it's safe for you, tell your doctor if you:
- have had an allergic reaction to glimepiride or any other medicines in the past
- have severe kidney or liver disease
- have G6PD-deficiency (an inherited condition affecting red blood cells)
- are due to have surgery
- are pregnant, trying to get pregnant or breastfeeding
When to take glimepiride 4mg?
Glimepiride is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is ...
When is glimepiride working the hardest?
amaryl (glimepiride) effect/time: amaryl ( glimepiride) works by stimulating beta cells in pancreas to produce insulin .it should start working right away as it gets absorped, if after two weeks you dont see its effect on blood sugar, than you will need to increase the dose gradually to the maximum dose , to see the ful effect.often you have to …
How quickly should glimepiride be working?
Can you take 8 mg of glimepiride?
Your dose of glimepiride may be adjusted based on your blood sugar levels. The maximum recommended dose is 8 mg taken once per day.
Can I take glimepiride twice a day?
Conclusions: Glimepiride is equally effective whether administered once or twice daily. Glimepiride seems to stimulate insulin production primarily after meals, when plasma glucose concentrations are highest, but controls blood glucose throughout the day.
Can you overdose on glimepiride?
A glimepiride overdose can cause life-threatening hypoglycemia. Symptoms of severe hypoglycemia include extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions).
Can you take glimepiride three times a day?
A dosage of more than 4 mg glimepiride per day gives better results only in exceptional cases. The maximum recommended dose is 6 mg glimepiride per day. In patients not adequately controlled with the maximum daily dose of metformin, concomitant glimepiride therapy can be initiated.
How many hours does glimepiride last?
Glimepiride starts reducing blood sugar levels in about 2-3 hours after a single dose. The effectiveness of the medicine can last for up to 24 hours. If Glimepiride stops working after some time, your doctor may increase the dose or add another diabetic drug such as metformin to your treatment plan.
How much does glimepiride lower blood sugar?
Doctors will order regular blood tests to check a person's blood sugar levels. People may receive these tests up to four times per year. Sulfonylureas, including glimepiride, can decrease A1C values by about 1.5% .
Is glimepiride stronger than metformin?
Metformin was only more effective than glimepiride in controlling the levels of total cholesterol (TC, 0.33 [0.03, 0.63], P = 0.03), low-density lipoprotein (LDL, 0.35 [0.16, 0.53], P = 0.0002) and triglycerides (TG, 0.26 [0.05, 0.46], P = 0.01).
Can I take metformin and glimepiride at the same time?
Can you take Amaryl (glimepiride) and metformin together? Yes. It is common for people to be taking both metformin and Amaryl (glimepiride) to lower their blood sugars if they have type 2 diabetes.
What should you avoid while taking glimepiride?
What drugs and food should I avoid while taking Glimepiride (Amaryl)? Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment. Avoid exposure to sunlight or tanning beds.
When is the best time of day to take glimepiride?
You'll usually take glimepiride once a day. Take this medicine with food. Most people take it in the morning with their breakfast. If you do not eat breakfast, make sure you take it with your first meal of the day.
What is normal blood sugar by age?
Target blood sugar levels for children and adolescents with diabetesTarget blood sugar levels for children and adolescents with diabetesAge 6-12Blood sugar in mg/dLFasting80-180Before meal90-1801-2 hours after eatingUp to 1401 more row
Does glimepiride make you sleepy?
This medicine may cause dizziness, drowsiness, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert or able to think well. This medicine may cause serious types of allergic reactions, including anaphylaxis.
How it works
Glimepiride belongs to a class of drugs called sulfonylureas. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Quinolone antibiotics
These drugs can increase the effect of glimepiride and cause low blood sugar. Examples of these drugs include:
Antifungals
These drugs can increase the effect of glimepiride and cause low blood sugar. Examples of these drugs include:
Drug that treats eye infections
Chloramphenicol can increase the effect of glimepiride and cause low blood sugar.
Drug that treats high cholesterol and triglycerides
Clofibrate can increase the effect of glimepiride and cause low blood sugar.
Drugs that treat depression
These drugs can increase the effect of glimepiride and cause low blood sugar. Examples of these drugs include:
What are the side effects of taking glimepiride?
Downsides. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Low blood sugar levels (hypoglycemia), dizziness, lack of energy, headache, and nausea.
How to avoid glimepiride?
Avoid alcohol. Ensure you wear an alert bracelet or carry a card that says you have diabetes and are taking glimepiride. Follow the diet and exercise program given to you by your doctor. Make sure you eat regular meals and always carry a reliable source of glucose with you (such as glucose tablets).
How does glimepiride work?
How it works. Glimepiride may be used in the treatment of type 2 diabetes. Glimepiride stimulates the release of insulin from beta cells within the pancreas. Glimepiride belongs to the class of medicines known as sulfonylureas. 2. Upsides. May be used to improve blood sugar control in adults with type 2 diabetes.
Why is glimepiride used?
Glimepiride is used to help maintain blood sugar control in people with type 2 diabetes. It may cause nausea and people who take glimepiride should always be alert for symptoms of hypoglycemia (low blood sugar).
How long does it take for glimepiride to work?
Glimepiride takes about two to three hours to reach its maximal effect after a single dose. 7. Interactions. Medicines that interact with glimepiride may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with glimepiride.
What medications interact with glimepiride?
Speak to your doctor about how drug interactions should be managed. Common medications that may interact with glimepiride include: aloe vera. antidepressants such as amitriptyline, clomipramine, or SSRIs. antifungal agents, such as fluconazole, miconazole, or voriconazole. beta-blockers, such as acebutolol and metoprolol.
Can glimepiride cause hypoglycemia?
May cause severe hypoglycemia ( low blood sugar) which may affect your ability to drive or perform hazardous tasks. Hypoglycemia is more likely to occur with low-calorie diets, after severe or prolonged exercise, or when glimepiride is taken with alcohol. Always keep simple sugars on hand in case of hypoglycemia.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
How much glimepiride should I take?
People should take it with breakfast or the first meal of the day. People will usually start on a low dose of glimepiride, which is about 1 mg or 2 mg once per day.
What are the side effects of glimepiride?
Possible side effects of glimepiride include headaches, nausea, and dizziness. The most common side effect people may experience when taking glimepiride, is hypoglycemia. This is the medical term for blood sugar levels that fall below 70 milligrams per deciliter. (mg/dL).
What is the first line of treatment for elevated glucose levels?
The first-line treatment for elevated levels is metformin (Glucophage). However, a doctor may prescribe glimepiride for people who are unable to take metformin. after 3 months of taking metformin, the doctor may choose to add glimepiride. Alternatively, they may add another type of antidiabetic medication.
What is glimepiride used for?
Glimepiride is an oral medication that doctors prescribe to treat type 2 diabetes. Glimepiride belongs to a class of drugs called sulfonylureas. Sulfonylureas work by increasing the amount of insulin released from the pancreas.
Why is glimepiride prescribed?
Doctors prescribe glimepiride to help control blood sugar levels in people with type 2 diabetes. Glimepiride increases the risk of dangerously low blood sugar levels. People who take this medication must, therefore, check their blood sugar levels regularly. Glimepiride may also cause other side effects, especially when taken with certain other ...
How much glucose should I take for seizures?
The American Diabetes Association recommend that people follow the 15-15 rule when taking glucose to treat hypoglycemia. The 15-15 rule recommends that people consume 15 grams (g) of carbohydrate and check their blood sugar levels 15 minutes later.
Can a doctor prescribe sulfonylurea?
In some cases, a doctor may go ahead and prescribe a sulfonylurea to a person with a sulfa allergy. However, the doctor will monitor the person closely to check for early signs of a repeat allergic reaction. As well as sulfa allergy, some people may experience other general hypersensitivities to the drug.

How It Works
Glimepiride is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications.
May Treat: Type 2 diabetes mellitus
Brand Names: Amaryl
Drug Class: Antihyperglycemic - Sulfonylurea Derivatives
Availability: Prescription Required
Pregnancy: Consult a doctor before using
May Treat: Type 2 diabetes mellitus
Brand Names: Amaryl
Drug Class: Antihyperglycemic - Sulfonylurea Derivatives
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: This drug should not be given to breastfeeding mothers
Alcohol: Avoid intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Upsides
Downsides
Bottom Line
Tips
Interactions
- May be used to improve blood sugar control in adults with type 2 diabetes.
- Used in addition to diet and exercise.
- Taken orally (by mouth).
- Available in 1mg, 2mg, and 4mg tablets.
References
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. Low blood sugar levels (hypoglycemia), dizziness, lack of energy, headache, and nausea. 2. May cause severe hypoglycemia (low blood sugar) which may affect your ability to drive or perform hazardous tas…
Further Information
- Glimepiride is used to help maintain blood sugar control in people with type 2 diabetes. It may cause nausea and people who take glimepiride should always be alert for symptoms of hypoglycemia (low...