Precautions
Yes. Tylenol PM Extra Strength is 500 mg of acetaminophen and 25 mg of diphenhydramine. The “regular” Extra Strength Tylenol is 500 mg of acetaminophen. Benadryl is 25 mg of diphenhydramine. So, taken together, it is an exact substitute for Tylenol PM Extra Strength.
Is it OK to take Tylenol PM and Benadryl together?
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. These medications may cause some risk when taken together.
Can you take promethazine with Tylenol PM?
Tylenol (acetaminophen) or axion: Yes no problem taking them both together as prescribed. Most medication if used as prescribed are safe. Is it safe to take robaxin and tylenol (acetaminophen) if i have a concussion? No and yes: Tylenol (acetaminophen) is fine, but i would recommend against use of robaxin.
Can I take Robaxin with Tylenol PM?
This is equal to about 56 to 112 tablets. The lethal dose may be smaller in children and the elderly. Acetaminophen is the active ingredient in Tylenol, an over-the-counter painkiller. According to some estimates, the lethal dose of acetaminophen in adults is approximately 7500 to 10,000 mg.
How much Tylenol is a lethal dose?
How many milligrams of Benadryl is in Tylenol PM?
Tylenol PM is an OTC medication used to treat headaches and other body pains while helping people fall asleep. As an oral tablet, it generally contains 25 mg of diphenhydramine hydrochloride and 500 mg of acetaminophen.
Are Tylenol PM and Benadryl the same?
Tylenol PM, specifically, has acetaminophen (the active ingredient in Tylenol) combined with diphenhydramine. Acetaminophen, when taken in large doses, can potentially affect the liver so should be used judiciously. Benadryl, Unisom and Sominex, for example, do not contain acetaminophen, only diphenhydramine.
Does Tylenol PM contain diphenhydramine?
TYLENOL® PM and SIMPLY SLEEP® both contain the active ingredient diphenhydramine. Read more about diphenhydramine and high blood pressure below. Click here to buy a TYLENOL® PM product.
How many mg of diphenhydramine can you take?
Diphenhydramine HCl comes in 25 mg and 50 mg strengths (Benadryl is a common brand). For adults and teens, the diphenhydramine dosage is 25 to 50 mg every 4 to 6 hours. The maximum amount you should take in one day is 300 mg. Keep in mind, taking higher doses can increase the risk of side effects, including drowsiness.
Can I mix Benadryl and Tylenol PM?
Interactions between your drugs No interactions were found between Benadryl and Tylenol PM. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
What is the difference between acetaminophen and diphenhydramine?
Acetaminophen is a pain reliever and a fever reducer. Diphenhydramine is an antihistamine. Acetaminophen and diphenhydramine is a combination medicine used to treat occasional insomnia associated with minor aches and pains.
How much of diphenhydramine is lethal?
With ingestions greater than 1 gram, diphenhydramine may result in delirium, psychosis, seizures, coma, and death. There is an even greater risk of seizures, coma, and death when ingestions are greater than 1.5 grams of diphenhydramine. Fatal deaths have also been reported with oral doses greater than 20 mg/kg.
Is it OK to take Tylenol PM every night?
Is it safe to regularly take Tylenol PM? It's not a good idea to take it long-term, according to our medical advisors. Tylenol PM contains two medications—the pain reliever acetaminophen and an antihistamine (diphenhydramine) to help with insomnia.
What is diphenhydramine HCl 25mg?
Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness.
Can you take 100 mg of diphenhydramine?
The maximum oral dose of diphenhydramine for adults is generally reported as 100mg for a single dose or no more than 300mg in 24 hours, but this can vary depending on what condition diphenhydramine is being used for, the salt of diphenhydramine used (there are two salts available in the United States, diphenhydramine ...
How many 25 mg diphenhydramine can I take?
Do not take more than 6 doses in 24 hours. Use only as directed. 2 to 4 chewable tablets (25 mg to 50 mg) every 4 to 6 hours or as directed by a doctor. 1 to 2 chewable tablets (12.5 mg to 25 mg) every 4 to 6 hours or as directed by a doctor.
How long does it take for diphenhydramine to kick in?
Diphenhydramine (Benadryl) starts to work pretty quickly. You can expect to it to kick in within about 15 to 30 minutes. Its full effects can be felt around 2 hours after your dose. Can diphenhydramine (Benadryl) be used long-term?
Who should not take Tylenol PM?
Tylenol PM is not for use in anyone younger than 12 years old. Do not use the medicine to make a child sleepy. Death can occur from the misuse of antihistamines in very young children. Do not use this medicine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.
Is Benadryl a good sleep aid?
Although antihistamines like Benadryl will make you feel sleepy, they're not a great choice when it comes to treating insomnia. Not only can they affect your sleep quality, but they'll also become less effective very quickly, meaning you may not notice any benefits if you use them often.
Is it OK to take Benadryl every night?
Is it safe to take diphenhydramine every night? You should not take diphenhydramine every night. While it may be helpful during limited periods of insomnia, your body will build up a tolerance for the medication over time, and it will no longer have the desired effect.
Is it OK to take a Tylenol PM every night?
Is it safe to regularly take Tylenol PM? It's not a good idea to take it long-term, according to our medical advisors. Tylenol PM contains two medications—the pain reliever acetaminophen and an antihistamine (diphenhydramine) to help with insomnia.
What’s the difference between acetaminophen (Tylenol) and Tylenol PM (acetaminophen / diphenhydramin...
Acetaminophen (Tylenol) and Tylenol PM (acetaminophen / diphenhydramine) are both medications that treat pain and fever, but Tylenol PM (acetaminop...
Can I drink alcohol while taking Tylenol PM (acetaminophen / diphenhydramine)?
Avoid drinking alcohol while taking Tylenol PM (acetaminophen / diphenhydramine). Drinking alcohol while taking this medication can raise your risk...
How long will it take for Tylenol PM (acetaminophen / diphenhydramine) to work?
For sleep, Tylenol PM (acetaminophen / diphenhydramine) usually works to cause drowsiness within 30 minutes. This is why it’s best to take it 30 mi...
Can I take Tylenol PM (acetaminophen / diphenhydramine) every day?
Tylenol PM (acetaminophen / diphenhydramine) is meant to be taken on an as-needed basis and not every day for a long period of time. The American A...
Is Tylenol PM (acetaminophen / diphenhydramine) safe to use during pregnancy?
The ingredients in Tylenol PM (acetaminophen / diphenhydramine) haven't been studied well in pregnant women. In general, acetaminophen is the medic...
Before Taking This Medicine
Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages...
How Should I Take Tylenol Pm?
Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not take this medicine for longer than recommended. Cold...
What Happens If I Miss A Dose?
Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.The first signs of an ac...
What Should I Avoid While Taking Tylenol Pm?
Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contai...
What Other Drugs Will Affect Tylenol Pm?
Other drugs may interact with acetaminophen and diphenhydramine, including prescription and over-the-counter medicines, vitamins, and herbal produc...
How long can you take Tylenol PM?
Tylenol PM is not for use in anyone younger than 12 years old. Do not use the medicine to make a child sleepy. Death can occur from the misuse of antihistamines in very young children. Do not use this medicine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.
What are the side effects of Tylenol PM?
constipation; decreased urination; dry eyes, blurred vision; or. dry mouth, nose, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tylenol PM side effects (more detail)
What is the difference between acetaminophen and diphenhydramine?
Acetaminophen is a pain reliever and a fever reducer. Diphenhydramine is an antihistamine. Tylenol PM is a combination medicine used to treat occasional insomnia associated with minor aches and pains. Tylenol PM is not for use in treating sleeplessness without pain, or sleep problems that occur often.
What is Tylenol PM used for?
Tylenol PM is also used to treat runny nose, sneezing, itchy nose and throat, and pain or fever caused by allergies, the common cold, or the flu. Tylenol PM may also be used for purposes not listed in this medication guide.
Can you die from taking too much acetaminophen?
Use this medicine exactly as directed. An overdose of acetaminophen can damage your liver or cause death. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.
Can Tylenol PM be taken with other medications?
Ask a doctor or pharmacist before using Tylenol PM with any other medicines, especially drugs that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures ). Tell your doctor about all your current medicines and any medicine you start or stop using.
Can you take Tylenol PM for short term?
Tylenol PM is only for short-term use until your symptoms clear up. Do not take more of this medicine than is recommended. An overdose of acetaminophen can damage your liver or cause death. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.
What is Tylenol PM?
Tylenol PM (Acetaminophen And Diphenhydramine) Acetaminophen is a pain reliever and a fever reducer. Diphenhydramine is an antihistamine. Acetaminophen and diphenhydramine is a combination medicine used to treat occasional insomnia associated with minor aches and pains. This medicine is not for use in treating sleeplessness without pain, ...
What to do if you overdose on Tylenol?
If you think you or someone else may have overdosed on: Tylenol PM (Acetaminophen And Diphenhydramine) , call your doctor or the Poison Control center. (800) 222-1222. If someone collapses or isn't breathing after taking Tylenol PM (Acetaminophen And Diphenhydramine), call 911. 911.
Does acetaminophen help with sleep problems?
This medicine is not for use in treating sleeplessness without pain, or sleep problems that occur often. Acetaminophen and diphenhydramine is also used to treat minor aches and pains such as headache, back pain, joint or muscle pain, tooth pain, or menstrual cramps. Acetaminophen and diphenhydramine is also used to treat runny nose, sneezing, ...
Can acetaminophen cause skin rash?
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Can you take acetaminophen with diphenhydramine?
Acetaminophen and diphenhy dramine is only for short-term use until your symptoms clear up. Do not take more of this medicine than is recommended. An overdose of acetaminophen can damage your liver or cause death. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.
Can you use Tylenol PM in larger amounts?
Use Tylenol PM (Acetaminophen And Diphenhydramine) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Use exactly as directed on the label, or as prescribed by your doctor.
Can you overdose on acetaminophen?
This includes medicines for pain, fever, swelling, cold/flu symptoms, or anti-itch medicine used on the skin. Using too much acetaminophen or diphenhydramine can lead to a fatal overdose. Drinking alcohol may increase your risk of liver damage while taking acetaminophen.
Can you take acetaminophen with any other medication?
with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. with any other product containing diphenhydramine, even one used on skin. in children under 12 years of age.
Can acetaminophen cause liver damage?
Severe liver damage may occur if you take. more than 4,000 mg of acetaminophen in 24 hours. with other drugs containing acetaminophen. 3 or more alcoholic drinks every day while using this product. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening. blisters.
Product Description
Tylenol PM Extra Strength Liquid helps relieve minor aches and pains and helps you fall asleep fast. This nighttime liquid medicine provides 1,000 milligrams of acetaminophen pain reliever and 50 milligrams of diphenhydramine HCl sleep aid per 30 mL dose.
Important information
Active ingredients: (per 30mL dose) Acetaminophen 1,000 mg Diphenhydramine HCl 50 mg Purposes - Pain reliever, nighttime sleep aid Inactive ingredients: anhydrous citric acid, FD&C blue no. 1, FD&C red no. 40, flavors glycerin, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sodium citrate, sorbitol, sucralose, sucrose
Usual Adult Dose for Pain
Acetaminophen 325 mg/diphenhydramine 12.5 mg: 2 tablets orally every 4 to 6 hours as needed Maximum dose: 8 tablets in 24-hours Acetaminophen 500 mg/diphenhydramine 12.5 mg: 2 tablets orally every 6 hours as needed Maximum dose: 6 tablets in 24-hours Comments: -The maximum total daily dose of acetaminophen should not exceed 4000 mg; when calculating daily dose, must account for all formulations of acetaminophen. Uses: -For temporary relief of minor aches and pains due to headache, backache, muscular aches, arthritis, pain, colds, flu, fever, toothache, premenstrual and menstrual cramps. -For temporary relief of runny nose, sneezing, and itchy nose and throat..
Usual Adult Dose for Headache
Acetaminophen 325 mg/diphenhydramine 12.5 mg: 2 tablets orally every 4 to 6 hours as needed Maximum dose: 8 tablets in 24-hours Acetaminophen 500 mg/diphenhydramine 12.5 mg: 2 tablets orally every 6 hours as needed Maximum dose: 6 tablets in 24-hours Comments: -The maximum total daily dose of acetaminophen should not exceed 4000 mg; when calculating daily dose, must account for all formulations of acetaminophen. Uses: -For temporary relief of minor aches and pains due to headache, backache, muscular aches, arthritis, pain, colds, flu, fever, toothache, premenstrual and menstrual cramps. -For temporary relief of runny nose, sneezing, and itchy nose and throat..
Usual Adult Dose for Insomnia
Acetaminophen 1000 mg/diphenhydramine 50 mg orally at bedtime Maximum dose: 1 dose in 24-hours Comments: -The maximum total daily dose of acetaminophen should not exceed 4000 mg; when calculating daily dose, must account for all formulations of acetaminophen. -Diphenhydramine hydrochloride 25 mg is approximately equal to diphenhydramine citrate 38 mg; the above dosing is provided as diphenhydramine hydrochloride. Use: For the temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness..
Usual Pediatric Dose for Pain
12 years or older: Acetaminophen 325 mg/diphenhydramine 12.5 mg: 2 tablets orally every 4 to 6 hours as needed Maximum dose: 8 tablets in 24-hours Acetaminophen 500 mg/diphenhydramine 12.5 mg: 2 tablets orally every 6 hours as needed Maximum dose: 6 tablets in 24-hours Comments: -The maximum total daily dose of acetaminophen should not exceed 4000 mg; when calculating daily dose, must account for all formulations of acetaminophen. Uses: -For temporary relief of minor aches and pains due to headache, backache, muscular aches, arthritis, pain, colds, flu, fever, toothache, premenstrual and menstrual cramps. -For temporary relief of runny nose, sneezing, and itchy nose and throat..
Usual Pediatric Dose for Headache
12 years or older: Acetaminophen 325 mg/diphenhydramine 12.5 mg: 2 tablets orally every 4 to 6 hours as needed Maximum dose: 8 tablets in 24-hours Acetaminophen 500 mg/diphenhydramine 12.5 mg: 2 tablets orally every 6 hours as needed Maximum dose: 6 tablets in 24-hours Comments: -The maximum total daily dose of acetaminophen should not exceed 4000 mg; when calculating daily dose, must account for all formulations of acetaminophen. Uses: -For temporary relief of minor aches and pains due to headache, backache, muscular aches, arthritis, pain, colds, flu, fever, toothache, premenstrual and menstrual cramps. -For temporary relief of runny nose, sneezing, and itchy nose and throat..
Usual Pediatric Dose for Insomnia
12 years or older: Acetaminophen 1000 mg/diphenhydramine 50 mg orally at bedtime Maximum dose: 1 dose in 24-hours Comments: -The maximum total daily dose of acetaminophen should not exceed 4000 mg; when calculating daily dose, must account for all formulations of acetaminophen. -Diphenhydramine hydrochloride 25 mg is approximately equal to diphenhydramine citrate 38 mg; the above dosing is provided as diphenhydramine hydrochloride. Use: For the temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness..
Precautions
CONTRAINDICATIONS: -Hypersensitivity to the active substances or any product excipients -Do not use with any other diphenhydramine-containing product, including topical products -Do not use in children less than 12 years -Should not use with any other acetaminophen-containing products Safety and efficacy have not been established in patients younger than 12 years. Consult WARNINGS section for additional precautions..
What is Tylenol PM?
Tylenol PM. Tylenol PM is a medication which contains: The pain reliever component of this medication (acetaminophen) is useful for the treatment of mild to moderate pain. The mechanism of acetaminophen is not quite understood but is believed to inhibit prostaglandins which serve a role in inflammation and pain.
How long should you separate Tylenol PM and Benadryl?
Doses of each should be separated be at least four to six hours.
What are the side effects of diphenhydramine?
The use of these medications together will result in an additive effect of toxicities and not in therapeutic benefit as both medications contain diphenhydramine in the active ingredients. Effects which may be intensified include: 1 Sedation 2 Drowsiness 3 Dry mouth 4 Dry eyes 5 Constipation
Does Benadryl help with motion sickness?
The same anticholinergic, sedating and drowsy side effects are expected with this medication as with Tylenol PM. Each dose of Benadryl (e.g. tablet, capsule) contains 25 mg of diphenhydramine.
Is Benadryl a first generation antihistamine?
Benadryl. Unlike Tylenol PM, Benadryl only contains diphenhydramine which is a 1st generation antihistamine. First-generation antihistamines are known for their sedative effects and relatively short duration of action. The common uses of this medication are for allergy relief, insomnia and the prevention or treatment of motion sickness.
Does acetaminophen help with allergic rhinitis?
The antihistamine component (diphenhydramine) is useful for aiding in sleep or allergic rhinitis symptoms due to the anticholinergic effect that antihistamines exert on the body.
Can you take Benadryl with Tylenol?
Therefore, if necessary, you can safely take one Benadryl tablet with Tylenol PM to equal a dose of 50 mg of diphenhydramine, but this would be the maximum dose. This also isn't generally recommended due to the risk of overdosing using multiple medications.
Know the facts
Chronic stress leads to lack of sleep and other manifestations of pain. Lack of sleep is linked to poor health and has been associated with the following health risks:
Always read and follow your pain medication label
Nighttime sleep aids containing NSAIDs like ibuprofen (e.g. Advil ® PM, MOTRIN ® PM) and naproxen sodium (e.g. Aleve ® PM) can produce several effects on your body that may further worsen high blood pressure. NSAIDs can: