Fluconazole Side Effects
- Common Side Effects of Fluconazole. Headache is the most common side effect of taking fluconazole. Other side effects include: nausea, diarrhea, vomiting, rash, and stomach pain.
- Serious Side Effects of Fluconazole
- Rare Side Effects of Fluconazole
What do I do if I take too much fluconazole?
More serious (but less common) side effects include:
- QT prolongation
- Anaphylactic reactions
- Cholestasis
- Liver failure/liver issues
- Jaundice
Does fluconazole do any damage to the kidneys?
Increased side effects can include kidney damage. Your doctor will check your blood for signs of kidney damage while you’re taking fluconazole. If you show signs of kidney damage, your doctor may lower your doses of these drugs or stop them completely until your treatment with fluconazole is done. Theophylline.
Can fluconazole cause flu like symptoms?
flu-like symptoms; dark urine; pale stools; seizures; rash; blistering or peeling skin; hives; itching; swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs; difficulty breathing or swallowing; Fluconazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Does fluconazole affect the pill?
Fluconazole is not likely to affect your contraception, including the combined pill or emergency contraception. If taking fluconazole makes you vomit or have severe diarrhoea for more than 24 hours, your contraceptive pills may not protect you from pregnancy.
How common are side effects of fluconazole?
The following treatment-related clinical adverse events occurred at an incidence of 1% or greater in 4048 patients receiving DIFLUCAN for 7 or more days in clinical trials: nausea 3.7%, headache 1.9%, skin rash 1.8%, vomiting 1.7%, abdominal pain 1.7%, and diarrhea 1.5%.
How long does the side effects of fluconazole last?
The enzyme inhibiting effect of fluconazole persists for 4 to 5 days after discontinuation of fluconazole. Although single-dose fluconazole is effective for vaginal yeast infections, there is a higher risk of adverse reactions (26%) versus intravaginal agents (16%).
What are the side effects of fluconazole 150mg?
Nausea, vomiting, diarrhea, stomach upset/pain, headache, dizziness, or hair loss may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What should I avoid while taking fluconazole?
Side effects from Caffeine may get worse if you take Fluconazole. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. You may need to limit your Caffeine intake. Common foods and beverages containing caffeine include coffee, teas, colas and chocolate.
Does fluconazole make you tired?
Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally.
Does fluconazole make it worse before it gets better?
It's going to get worse before it gets better, trust me. When I take it, it usually gets worse for about 2-3 days. On the third day if I am not feeling better I'll take another dose and my symptoms will be gone within 24 hours.
How do I know if fluconazole is working?
If you are taking fluconazole to prevent an infection, the medicine kills any fungus as it starts to appear. Fluconazole is used for many different fungal infections. If you have vaginal thrush, balanitis or oral thrush, your symptoms should be better within 7 days of taking fluconazole.
Can fluconazole cause anxiety?
The commonest side effects were dry skin (xerosis), hair loss (alopecia) and fatigue. Other side effects included nausea and vomiting, loss of appetite, headache, joint discomfort, dry lips, dry mouth and loss of taste, dizziness or low blood pressure, neuropathy, impotence, anxiety, and brittle nails.
How safe is fluconazole?
A prescription-event monitoring (PEM) study has confirmed that fluconazole, a bis-triazole oral antifungal drug, is a safe and effective treatment for vaginal candidiasis.
Why is fluconazole a hazardous drug?
Known Clinical Effects: Adverse effects most commonly reported in clinical use include skin rash, headache, nausea, and abdominal pain. Rare cases of serious liver damage and allergic reactions have been reported.
Is fluconazole hard on the liver?
The severity of liver injury from fluconazole ranges from mild and transient enzyme elevations to clinically apparent hepatitis to acute liver failure and death. Most patients recover with stopping fluconazole, but resolution may be slow requiring 3 to 4 months. Rechallenge may lead to recurrence and should be avoided.
Does fluconazole push the yeast out?
Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast (fungus).
What are the symptoms of a syringe?
hoarseness. increased thirst. irregular or slow heart rate. joint or muscle pain. loss of bladder control. lower back or side pain. mood changes. muscle pain or cramps. muscle spasm or jerking of the arms and legs.
Can medicine cause side effects?
Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
What is fluconazole used for?
Fluconazole is used to treat serious fungal or yeast infections , such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. This medicine works by killing the fungus or yeast, or preventing its growth.
How old is too old to take fluconazole?
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluconazole in children 6 months to 13 years of age. However, safety and efficacy have not been established in children younger than 6 months of age.
Can elderly people take fluconazole?
However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving fluconazole.
What is the name of the allergic reaction that causes yellowing of the skin?
a type of allergic reaction called angioedema. a yellowing of the eyes or skin from buildup of bilirubin called jaundice. a type of skin disorder called acute generalized exanthematous pustulosis. a type of significant allergic skin reaction called DRESS syndrome.
Are you currently using fluconazole?
This survey is being conducted by the WebMD marketing sciences department.
What are the side effects of taking fluconazole?
The levels of these drugs may be increased in your body when taken with fluconazole. Increased side effects include slower breathing, confusion, and drowsiness. Carbamazepine.
How does fluconazole work?
Fluconazole works by blocking the ability of the fungi Candida and Cryptococcus to reproduce. For people with infections from these fungi, this drug helps to get rid of the infection. For people at higher risk of candidiasis, it helps to prevent infection.
Why is fluconazole used for candida?
Why it’s used. Fluconazole is used to prevent and treat candidiasis. This condition is caused by infection with one of the many types of the fungus Candida. Examples of candidiasis include vaginal yeast infection, as well as oral yeast infection (thrush).
What is the name of the heart rhythm condition caused by fluconazole?
Terfenadine. When used with fluconazole at doses of 400 mg or higher, this drug can cause a life-threatening heart rhythm condition called torsades de pointes.
What is the brand name of diflucan?
Brand name: Diflucan . Fluconazole comes as a tablet or suspension you take by mouth. It also comes in an injectable form that can only be given to you by a healthcare provider. Fluconazole oral tablet is used to prevent and treat candidiasis, a fungal infection.
Can fluconazole cause headaches?
Taking this drug with fluconazole can cause muscle cramps, headache, low blood pressure, and seizures. Your doctor will measure blood levels of phenytoin while you’re taking fluconazole. Zidovudine. Increased side effects can include headache, tiredness, loss of appetite, nausea, and vomiting.
Can fluconazole cause slurred speech?
Phenytoin. Taking this drug with fluconazole can cause trouble with coordination, slurred speech, and confusion. Your doctor will measure blood levels of phenytoin while you’re taking fluconazole .
How long after fluconazole can you take voriconazole?
Monitoring for adverse events and toxicity related to voriconazole is recommended; especially, if voriconazole is started within 24 h after the last dose of fluconazole.
Does fluconazole reduce alfentanil?
A study observed a reduction in clearance and distribution volume as well as prolongation of t ½ of alfentanil following concomitant treatment with fluconazole.
Can you take fluconazole with olaparib?
Moderate inhibitors of CYP3A4 such as fluconazole increase olaparib plasma concentrations; concomitant use is not recommended. If the combination cannot be avoided, reduce the dose of olaparib as instructed in the Lynparza (Olaparib) Prescribing Information.
Does fluconazole decrease astemizole?
Concomitant administration of fluconazole with astemizole may decrease the clearance of astemizole.
Is fluconazole a CYP3A4 inhibitor?
Fluconazole is a moderate CYP2C9 and CYP3A4 inhibitor. Fluconazole is also a strong inhibitor of CYP2C19.
Does fluconazole increase halofantrine?
Fluconazole can increase halofantrine plasma concentration due to an inhibitory effect on CYP3A4.
Is Fluconazole a calcium channel blocker?
Certain calcium channel antagonists ( nifedipine, isradipine, amlodipine, verapamil, and felodipine) are metabolized by CYP3A4. Fluconazole has the potential to increase the systemic exposure of the calcium channel antagonists. Frequent monitoring for adverse events is recommended.
How to give fluconazole injection?
Fluconazole injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.
What is fluconazole?
Fluconazole is an antifungal medicine that is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood.
What should I avoid while using fluconazole?
Avoid driving or hazardous activity until you know how fluconazole will affect you. Your reactions could be impaired.
What other drugs will affect fluconazole?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
How is fluconazole taken?
Fluconazole oral is taken by mouth. Fluconazole injection is given as an infusion into a vein.
Why is fluconazole used for meningitis?
Fluconazole is also used to prevent fungal infection in people who have a weak immune system caused by cancer treatment, bone marrow transplant, or diseases such as AIDS. Fluconazole is also used to treat a certain type of meningitis in people with HIV or AIDS.
How to store fluconazole?
Store fluconazole at room temperature away from moisture and heat. Do not freeze.
What is fluconazole used for?
Fluconazole is used to prevent and treat a variety of fungal and yeast infections. It belongs to a class of drugs called azole antifungals. It works by stopping the growth of certain types of fungus.
Can fungusto cause nausea?
Stopping the medication too early may allow the fungusto continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or if it worsens. Side Effects . Nausea, vomiting, diarrhea, stomachupset/pain, headache, dizziness, or hair lossmay occur.
Can fluconazole prolong QT?
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using fluconazole, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Can fluconazole cause QT prolongation?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease. Fluconazole may cause a condition that affects the heartrhythm (QT prolongation).
Can you take fluconazole if you are allergic to it?
Precautions . Before taking fluconazole, tell your doctor or pharmacistif you are allergic to it; or to other azole antifungaldrugs (such as ketoconazole, itraconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Are you currently using Fluconazole?
This survey is being conducted by the WebMD marketing sciences department.
What are the side effects of fluconazole?
The most common side effects of fluconazole are feeling sick (nausea) and diarrhoea.
Why is fluconazole prescribed?
This is caused by a fungus called cryptococcus. Fluconazole can also be used to prevent a fungal infection developing. It is only prescribed if you are likely to get this sort of infection. This includes people who: keep getting vaginal thrush. have a weakened immune system. have had a bone marrow transplant.
How many doses of fluconazole are in a 5ml bottle?
It is best to take your capsules at the same time each day. The liquid usually comes in 2 different strengths: 50mg fluconazole in a 5ml spoonful (50mg/5ml) 200mg fluconazole in a 5ml spoonful (200mg/5ml) Use the plastic spoon that comes with your medicine to measure your dose.
How long does oral thrush last?
oral (mouth) thrush – 50mg a day, taken for 7 to 14 days. vaginal thrush or balanitis – 150mg, taken as a single dose. vaginal thrush that keeps coming back – 150mg, taken once every 72 hours for the first 3 doses, then take 150mg once a week for 6 months.
What is fluconazole used for?
About fluconazole. Fluconazole is an antifungal medicine. It's used to treat infections caused by different kinds of fungus. The most common cause of fungal infections is a yeast called candida. Fluconazole is used to treat many infections caused by candida including:
Can fluconazole cause anaphylaxis?
It happens rarely but it is possible to have a serious allergic reaction (anaphylaxis) to fluconazole.
Can you take fluconazole for babies?
Most adults and children can take fluconazole. It can also be prescribed for babies.