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fluconazole side effects

by Kacey Goodwin Published 4 years ago Updated 3 years ago

Side Effects
  • Chest tightness.
  • clay-colored stools.
  • difficulty with swallowing.
  • fast heartbeat.
  • hives, itching, or skin rash.
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.
  • light-colored stools.
  • stomach pain, continuing.
May 1, 2022

What do I do if I take too much fluconazole?

More serious (but less common) side effects include:

  • QT prolongation
  • Anaphylactic reactions
  • Cholestasis
  • Liver failure/liver issues
  • Jaundice

Does fluconazole do any damage to the kidneys?

Increased side effects can include kidney damage. Your doctor will check your blood for signs of kidney damage while you’re taking fluconazole. If you show signs of kidney damage, your doctor may lower your doses of these drugs or stop them completely until your treatment with fluconazole is done. Theophylline.

Can fluconazole cause flu like symptoms?

flu-like symptoms; dark urine; pale stools; seizures; rash; blistering or peeling skin; hives; itching; swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs; difficulty breathing or swallowing; Fluconazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Does fluconazole affect the pill?

Fluconazole is not likely to affect your contraception, including the combined pill or emergency contraception. If taking fluconazole makes you vomit or have severe diarrhoea for more than 24 hours, your contraceptive pills may not protect you from pregnancy.

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What happens to your body when you take fluconazole?

Fluconazole works by killing the fungus (or yeast) that is causing the infection. The medicine kills fungus by making holes in its cell membrane, so that the contents leak out. This treats the infection and allows your symptoms to get better.

What should I avoid while taking fluconazole?

Common medications that may interact with fluconazole include: anticoagulants or antiplatelet agents (blood thinners), such as warfarin, clopidogrel, (may prolong bleeding time) biologics, such as acalabrutinib, bosutinib, or entrectinib. albuterol.

How common are side effects of fluconazole?

The following treatment-related clinical adverse events occurred at an incidence of 1% or greater in 4048 patients receiving DIFLUCAN for 7 or more days in clinical trials: nausea 3.7%, headache 1.9%, skin rash 1.8%, vomiting 1.7%, abdominal pain 1.7%, and diarrhea 1.5%.

How long do symptoms last after taking fluconazole?

Fluconazole 150 mg capsules are an antifungal medication used to treat vaginal yeast infections caused by the yeast known as Candida. It works by stopping the growth of Candida. It usually starts to work within one day, but it may take 3 days for your symptoms to improve and up to 7 days for your symptoms to disappear.

What is the best time of day to take fluconazole?

Fluconazole can be taken at any time of day, and can be taken either before or after a meal. Swallow the capsule with a drink of water. Infections such as vaginal thrush can be treated with a single 150 mg dose; other infections require a course of treatment possibly lasting a number of weeks.

Does fluconazole make you tired?

Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally.

Does fluconazole flush out yeast?

Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast (fungus). This medication belongs to a class of drugs called azole antifungals.

Does fluconazole make it worse before it gets better?

It's going to get worse before it gets better, trust me. When I take it, it usually gets worse for about 2-3 days. On the third day if I am not feeling better I'll take another dose and my symptoms will be gone within 24 hours.

How long does it take for fluconazole to kick in?

by Drugs.com For mild, uncomplicated, infections fluconazole is prescribed as a single 150 mg dose and an improvement in symptoms is usually seen within one to three days.

How do you know when yeast infection is gone?

First, you will notice that vaginal discharge has returned to a normal consistency and smell. Second, you will notice that itching has gone away, alleviating much of the discomfort associated with the infection. Third, you will notice that any rash, swelling, or redness has subsided.

Can fluconazole cause anxiety?

The commonest side effects were dry skin (xerosis), hair loss (alopecia) and fatigue. Other side effects included nausea and vomiting, loss of appetite, headache, joint discomfort, dry lips, dry mouth and loss of taste, dizziness or low blood pressure, neuropathy, impotence, anxiety, and brittle nails.

What are the symptoms of a syringe?

hoarseness. increased thirst. irregular or slow heart rate. joint or muscle pain. loss of bladder control. lower back or side pain. mood changes. muscle pain or cramps. muscle spasm or jerking of the arms and legs.

Can medicine cause side effects?

Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

Are you currently using fluconazole?

This survey is being conducted by the WebMD marketing sciences department.

What is diflucan used for?

Diflucan is also used to treat cryptococcal meningitis, and prevention of Candida infections in patients treated with chemotherapy or radiation after bone marrow transplantation. Diflucan prevents growth of fungi by preventing production of the membranes that surround fungal cells. Common side effects of Diflucan include.

Does Diflucan cause angioedema?

Stevens-Johnson syndrome. Rarely, serious allergic reactions, including angioedema ( swelling of tissues ), may also occur . Drug interactions of Diflucan include hydrochlorothiazide, which increases the blood concentration of Diflucan by 40%.

Can you take diflucan while pregnant?

Use of Diflucan during pregnancy is not recommended. Diflucan is secreted in breast milk at concentrations similar to the mother's blood level. However, Diflucan is used for treating neonates with fungal infections and for treating lactation associated Candida infections.

Is diflucan good for a pregnant woman?

Use of Diflucan during pregnancy is not recommended. Available evidence suggests that use of Diflucan during breastfeeding has little risk.

Does fluconazole increase AUC?

Fluconazole increases the AUC of triazolam (single dose) by approximately 50%, Cmax by 20% to 32%, and increases t ½ by 25% to 50 % due to the inhibition of metabolism of triazolam.

Does diflucan increase terfenadine levels?

Another study at a 400 mg and 800 mg daily dose of fluconazole demonstrated that Diflucan taken in doses of 400 mg/day or greater significantly increases plasma levels of terfenadine when taken concomitantly. The combined use of fluconazole at doses of 400 mg or greater with terfenadine is contraindicated.

Is Fluconazole a calcium channel blocker?

Certain calcium channel antagonists ( nifedipine, isradipine, amlodipine, verapamil, and felodipine) are metabolized by CYP3A4. Fluconazole has the potential to increase the systemic exposure of the calcium channel antagonists. Frequent monitoring for adverse events is recommended.

How many milligrams of fluconazole are there?

The warning and class change came on the heels of a study that uncovered the disturbing fact that doses between 400 and 800 milligrams of fluconazole cause specific birth defects when women use the drug at these doses over the long-term during pregnancy.

When did the FDA start warning about fluconazole?

The first official warning only came in 2011 from the FDA when the agency upgraded the pregnancy class of higher doses of fluconazole from C to D, a classification that communicates this drug is known to cause harm to human fetuses.

What class of antifungal is fluconazole?

Fluconazole belongs to the triazole class of antifungal medications. These drugs treat and cure fungal infections by acting on an enzyme on fungal cells. The result is that it slows the growth of the fungus and slows and stops the spread of the infection. The FDA approved fluconazole to treat a number of fungal infections, ...

Where does fluconazole come from?

Fluconazole Uses. Fluconazole came from Pfizer, the major drug maker that developed it in the 1980s and received U.S. Food and Drug Administration (FDA) approval in 1990. Pfizer marketed and sold the drug as Diflucan. Since 1990 the patent has run out and while Pfizer still offers Diflucan, other companies have also gotten in on making ...

Can fluconazole be given to AIDS patients?

Patients with cancer or AIDS who are vulnerable to developing fungal infections may be given fluconazole to prevent fungal infections. In fewer cases the drug may be used to treat skin, eye and prostate fungal infections.

Does fluconazole cause miscarriages?

As if all the previous side effects were not troubling enough, fluconazole has recently been found to cause birth defects and miscarriages. Since the drug came on the market in 1990 millions of women and their babies were exposed to this risk without warning. The first official warning only came in 2011 from the FDA when the agency upgraded the pregnancy class of higher doses of fluconazole from C to D, a classification that communicates this drug is known to cause harm to human fetuses.

Does fluconazole help with yeast infections?

The FDA approved fluconazole to treat a number of fungal infections, especially yeast infections. These include vaginal, abdominal, esophageal, lung, blood, and mouth yeast infections. The FDA also approved fluconazole to treat fungal meningitis, a fungal infection of the covering membrane of the spine and brain called the meninges.

What to tell your doctor before taking fluconazole?

Before using fluconazole, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heartproblems (heart failure, slow heartbeat, QT prolongation in the EKG), family historyof certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Can fungusto cause nausea?

Stopping the medication too early may allow the fungusto continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or if it worsens. Side Effects . Nausea, vomiting, diarrhea, stomachupset/pain, headache, dizziness, or hair lossmay occur.

Can fluconazole be taken in breast milk?

Discuss the risks and benefits with your doctor. Fluconazole passes into breastmilk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Does fluconazole affect QT?

Many drugs besides fluconazolemay affect the heartrhythm (QT prolongation), including pimozide, quinidine, macrolide antibiotics(such as erythromycin), among others. Fluconazole can slow down the removal of other medications from your body, which can affect how they work.

Can fluconazole make you dizzy?

Talk to your doctor about using fluconazole safely. Although uncommon, this drug may make you dizzy. Alcohol or marijuana(cannabis) can make you more dizzy.

Can you take fluconazole if you are allergic to it?

Precautions . Before taking fluconazole, tell your doctor or pharmacistif you are allergic to it; or to other azole antifungaldrugs (such as ketoconazole, itraconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Can fluconazole cause QT prolongation?

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease. Fluconazole may cause a condition that affects the heartrhythm (QT prolongation).

What are the side effects of taking fluconazole?

The levels of these drugs may be increased in your body when taken with fluconazole. Increased side effects include slower breathing, confusion, and drowsiness. Carbamazepine.

How does fluconazole work?

Fluconazole works by blocking the ability of the fungi Candida and Cryptococcus to reproduce. For people with infections from these fungi, this drug helps to get rid of the infection. For people at higher risk of candidiasis, it helps to prevent infection.

Why is fluconazole used for candida?

Why it’s used. Fluconazole is used to prevent and treat candidiasis. This condition is caused by infection with one of the many types of the fungus Candida. Examples of candidiasis include vaginal yeast infection, as well as oral yeast infection (thrush).

What is the brand name of diflucan?

Brand name: Diflucan . Fluconazole comes as a tablet or suspension you take by mouth. It also comes in an injectable form that can only be given to you by a healthcare provider. Fluconazole oral tablet is used to prevent and treat candidiasis, a fungal infection.

How long does fungus treatment last?

The dose from day 2 on is usually 200–400 mg, taken once per day. Treatment length: Treatment typically lasts 10–12 weeks after a test called a cerebrospinal fluid culture no longer detects fungi.

What happens if you miss a dose of a drug?

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

What to do if you have serious side effects?

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

How many drugs interact with fluconazole?

Fluconazole has serious interactions with at least 84 different drugs. Fluconazole has moderate interactions with at least 186 different drugs. Fluconazole has mild interactions with at least 96 different drugs. This information does not contain all possible interactions or adverse effects.

What is fluconazole used for?

Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast ( fungus ). This medication belongs to a class of drugs called azole antifungals. Fluconazole is available under the following different brand names: Diflucan. Dosages of Fluconazole: Adult and Pediatric Dosage Forms and Strengths.

Is Candida krusei resistant to fluconazole?

Candida krusei is inherently resistant. Convenience and efficacy of single dose oral tablet of fluconazole regimen for the treatment of vaginal yeast infections should be weighed against acceptability of higher incidence of drug related adverse events with fluconazole (26%) versus intravaginal agents (16%)

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