Precautions
Key facts
- You'll usually take fluconazole once a day.
- Your dose and how long you take it for depends on the kind of infection you have.
- You can take fluconazole with or without food.
- The most common side effects of fluconazole are feeling sick (nausea) and diarrhoea.
How often to take fluconazole?
It is usually taken once a day, with or without food. You may need to take only one dose of fluconazole, or you may need to take fluconazole for several weeks or longer. The length of your treatment depends on your condition and on how well you respond to fluconazole.
How many fluconazole should I take?
Fluconazole injection is given as an infusion into a vein. You may take fluconazole oral with or without food. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Fluconazole injection is given as an infusion into a vein.
How to take fluconazole with antibiotics?
- Your initial infection wasn’t treated completely
- You’re creating humid or moist conditions for Candida to thrive
- You have a drug-resistant strain of yeast
- Your vaginal bacteria is out of whack
- You have a weakened immune system
When to take second fluconazole?
How long does idsa last?
How long does fluconazole last?
How long does it take for a cutaneous infection to resolve?
How long does oral thrush treatment last?
How long does 400 mg IV last?
See more
About this website
Usual Adult Dose For Vaginal Candidiasis
150 mg orally as a single doseInfectious Diseases Society of America (IDSA) Recommendations:-Uncomplicated vaginitis: 150 mg orally as a single dos...
Usual Adult Dose For Oral Thrush
Oropharyngeal candidiasis: 200 mg IV or orally on the first day followed by 100 mg IV or orally once a dayDuration of therapy: At least 2 weeks, to...
Usual Adult Dose For Candidemia
Doses up to 400 mg/day have been used.Comments:-Optimal therapeutic dose and therapy duration have not been established.Use: For systemic Candida i...
Usual Adult Dose For Esophageal Candidiasis
200 mg IV or orally on the first day followed by 100 mg IV or orally once a dayDuration of therapy: At least 3 weeks and for at least 2 weeks after...
Usual Adult Dose For Candida Urinary Tract Infection
50 to 200 mg IV or orally once a dayUse: For the treatment of Candida urinary tract infections and peritonitisIDSA Recommendations:-Asymptomatic cy...
Usual Adult Dose For Cryptococcal Meningitis - Immunocompetent Host
Acute infection: 400 mg IV or orally on the first day followed by 200 mg IV or orally once a dayDuration of therapy: 10 to 12 weeks after CSF cultu...
Usual Adult Dose For Cryptococcal Meningitis - Immunosuppressed Host
Acute infection: 400 mg IV or orally on the first day followed by 200 mg IV or orally once a dayDuration of therapy: 10 to 12 weeks after CSF cultu...
Usual Adult Dose For Cryptococcosis
IDSA Recommendations:Mild to moderate pulmonary infection and nonmeningeal, nonpulmonary infection if CNS disease ruled out, no fungemia, single si...
Usual Adult Dose For Fungal Infection Prophylaxis
400 mg IV or orally once a dayDuration of therapy: 7 days after neutrophil count rises above 1000 cells/mm3Comments:-If severe granulocytopenia (le...
Usual Adult Dose For Coccidioidomycosis - Meningitis
IDSA Recommendations: 400 mg orally once a dayComments:-Some experts start therapy with 800 to 1000 mg/day.-Patients who respond to therapy should...
Fluconazole (Oral Route) Proper Use - Mayo Clinic
Proper Use. Drug information provided by: IBM Micromedex Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
Fluconazole - How long does it take to work? - Drugs.com
For mild, uncomplicated, infections fluconazole is prescribed as a single 150 mg dose and an improvement in symptoms is usually seen within one to three days.. If a single dose does not completely relieve symptoms, or the infection is severe, fluconazole can be prescribed as three consecutive doses given three days apart.
Fluconazole dose recommendation in urinary tract infection
Objective: To identify the most appropriate dose of fluconazole for the treatment of symptomatic fungal urinary tract infection (UTI). Data sources: Primary literature identified through MEDLINE (1990-June 2000). Key search terms included fluconazole and urinary tract infection. Data synthesis: Fluconazole is approved for the treatment of candidal UTIs, but dosage recommendations are not ...
What is the usual recommanded fluconazole(diflucan) dosage for tinea ...
See below: The adult dose of Diflucan (fluconazole) for tinea versicolor is 150-300mg once weekly for 2-4 weeks. However recurrence of tv is not uncommon. Additionally, Diflucan (fluconazole) has the potential for serious side effects and interactions with other medications.
Fluconazole: Side effects, dosage, uses, and more
Fluconazole oral tablet is used to prevent and treat candidiasis, a fungal infection. It’s also used to treat meningitis (infection of the brain or spinal cord, or both). The tablet is available ...
How much esophageal candidiasis is prescribed?
The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight on the first day, followed by 6 mg per kg of body weight once a day, for at least 10 to 12 weeks. Children younger than 6 months of age—Use and dose must be determined by your doctor. For esophageal candidiasis:
How much mcg of bone marrow is needed for candidiasis?
For prevention of candidiasis during bone marrow transplantation: Adults—400 milligrams (mg) once a day. Children—Use and dose must be determined by your doctor.
How old do you have to be to take a syringe?
Children younger than 6 months of age—Use and dose must be determined by your doctor. Adults—200 milligrams (mg) on the first day, followed by 100 mg once a day for at least 2 weeks. Children 6 months to 13 years of age—Dose is based on body weight and must be determined by your doctor.
How long does it take to take 100 mg of esophageal candidiasis?
For esophageal candidiasis: Adults—200 milligrams (mg) on the first day, followed by 100 mg once a day for at least 3 weeks. Your doctor may increase your dose as needed. Children 6 months to 13 years of age—Dose is based on body weight and must be determined by your doctor.
How long does it take to take 200 mg of a sulfate supplement?
For cryptococcal meningitis: Adults—400 milligrams (mg) on the first day, followed by 200 mg once a day for at least 10 to 12 weeks. Your doctor may adjust your dose as needed. Children 6 months to 13 years of age—Dose is based on body weight and must be determined by your doctor.
How much mcg is in a day?
For other infections that may occur in different parts of the body: Adults—Doses of up to 400 milligrams (mg) per day. Children 6 months to 13 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 12 milligrams (mg) per kilogram (kg) of body weight per day.
How long can you keep a medicine in the refrigerator?
Keep from freezing. The mixed oral liquid should be kept in the refrigerator or at room temperature and used within 14 days.
What is fluconazole used for?
Fluconazole is a triazole medicine used to treat fungal infections. It is effective against a broad spectrum of fungi including: 1 Dermatophytes (tinea infections) 2 Yeasts such as candida and malassezia. 3 Systemic infections such as cryptococcosis and coccidioidomycosis
How long does it take for fluconazole to clear your system?
Fluconazole is well absorbed orally with or without food. It is widely distributed in body tissues. It takes 22 to 30 hours for half of the medication to be cleared from the bloodstream and may take several days of continuous treatment to reach a steady concentration.
Can fluconazole be taken with simvastatin?
Fluconazole should not be taken with the HMG Co-A reductase inhibitor simvastatin, and the dose of atorvastatin should be reduced. Pravastatin and rosuvastatin are preferable. Toxicity results in muscle pain and weakness, which may be serious.
Can you take fluconazole while pregnant?
Endocrine effects including enlarged breasts (in males), alopecia and impotence. Fluconazole should not normally be taken in pregnancy. Use during breast-feeding is acceptable as the drug level found in breast milk is very low.
Does celecoxib interact with fluconazole?
Celecoxib. Rifampicin may slightly decrease the concentration of fluconazole. Fluconazole is not thought to interact with the oral contraceptive pill. New Zealand approved datasheets are the official source of information for these prescription medicines, including approved uses and risk information.
Is fluconazole available over the counter?
In New Zealand, the Pharmaceutical Schedule subsidy of the capsules requires Specialist recommendation except for single-dose use, which is on general prescription and also available over the counter. Fluconazole binds to the fungal p450 enzymes and stops the cells making ergosterol, the main component of the cell wall.
Is fluconazole effective against fungi?
It is effective against a broad spectrum of fungi including: Dermatophytes (tinea infections) Yeasts such as candida and malassezia. Systemic infections such as cryptococcosis and coccidioidomycosis. In New Zealand, fluconazole is available as 50 mg, 150 mg and 200 mg capsules on prescription (Diflucan®). There is also a 2 mg/ml injection ...
How long after a valve replacement can you take fluconazole?
12 mg/kg/dose IV once daily as step-down therapy after lipid amphotericin B or echinocandin therapy in stable patients with negative blood cultures. In general, doses exceeding 600 mg are not recommended. For endocarditis, treat for at least 6 weeks after valve replacement. For infected cardiac hardware, treat for at least 4 to 6 weeks after hardware removal. When valve replacement or hardware removal is not possible, chronic suppressive therapy with fluconazole is recommended after initial treatment. Treat suppurative thrombophlebitis for at least 2 weeks after candidemia (if present) has cleared.
How long does amphotericin B deoxycholate last?
12 mg/kg/dose (Max: 800 mg/dose) PO on day 1, followed by 10 to 12 mg/kg/dose (Max: 800 mg/dose) PO once daily for at least 8 weeks after initial at least 4-week course of amphotericin B deoxycholate plus flucytosine is recommended by guidelines. Follow with fluconazole 6 mg/kg/dose (Max: 400 mg/dose) PO once daily. Maintenance therapy discontinuation is poorly studied in children; individualize therapy. The FDA-approved dosage is 12 mg/kg/dose PO on day 1, followed by 6 to 12 mg/kg/dose PO once daily for 10 to 12 weeks after cerebrospinal fluid culture becomes negative. Follow with 6 mg/kg/dose PO once daily for suppressive therapy.
How long to take amphotericin B?
12 mg/kg/dose (Max: 800 mg/dose) IV on day 1, followed by 10 to 12 mg/kg/dose (Max: 800 mg/dose) IV once daily for at least 8 weeks after initial at least 2-week course of amphotericin B plus flucytosine is recommended by guidelines. Opportunistic infections guidelines in HIV-infected patients include 12 mg/kg/dose (Max: 800 mg/dose) IV on day 1, followed by 10 to 12 mg/kg/dose (Max: 800 mg/dose) IV plus amphotericin B or flucytosine for at least 2 weeks as an alternative primary therapy, followed by fluconazole 10 to 12 mg/kg/dose (Max: 800 mg/dose) IV once daily for at least 8 weeks. Follow with fluconazole 6 mg/kg/dose (Max: 200 mg/dose) IV once daily. Maintenance therapy discontinuation is poorly studied in children; individualize therapy. The FDA-approved dosage is 12 mg/kg/dose IV on day 1, followed by 6 to 12 mg/kg/dose IV once daily for 10 to 12 weeks after cerebrospinal fluid culture becomes negative. Follow with 6 mg/kg/dose IV once daily for suppressive therapy.
How long does fluconazole stay in your system?
400 mg (6 mg/kg) IV once daily for at least 8 weeks after initial at least 2-week course of amphotericin B deoxycholate plus flucytosine is recommended by guidelines. Cryptococcosis guidelines suggest alternatives for primary therapy including fluconazole 800 mg IV once daily plus amphotericin B deoxycholate for 2 weeks, followed by fluconazole 800 mg IV once daily for at least 8 weeks; fluconazole 1,200 mg IV once daily plus flucytosine for 6 weeks; or fluconazole 1,200 to 2,000 mg IV once daily for 10 to 12 weeks. Opportunistic infections guidelines in HIV-infected patients suggest alternatives for primary therapy including fluconazole 800 mg IV once daily plus amphotericin B deoxycholate or liposomal amphotericin B for at least 2 weeks; fluconazole 400 or 800 mg IV once daily plus flucytosine for 2 weeks; or fluconazole 1,200 mg IV once daily for 2 weeks with all initial 2-week courses followed by fluconazole 400 mg IV once daily for at least 8 weeks. Follow with fluconazole 200 mg IV once daily for at least 12 months. Suppressive therapy discontinuation may be considered in patients receiving HAART therapy with a CD4 count more than 100 cells/mm3 and an undetectable or very low HIV RNA concentration for at least 3 months (after at least 12 months of antifungal therapy). The FDA-approved dosage is 12 mg/kg/dose IV on day 1, followed by 6 to 12 mg/kg/dose IV once daily for 10 to 12 weeks after cerebrospinal fluid culture becomes negative. Follow with 6 mg/kg/dose IV once daily for suppressive therapy.
How often should neonates be given?
Others have recommended a range of 6 to 12 mg/kg/dose IV every 24 to 72 hours.
How long does amphotericin B last?
Adults. 400 to 800 mg (6 to 12 mg/kg) IV once daily for 8 weeks after initial 2-week course of lipid formulation amphotericin B plus flucytosine, followed by fluconazole 200 to 400 mg IV once daily for 6 to 12 months is recommended by guidelines.
Does fluconazole affect renal function?
Other reported clinical experience has not identified differences in responses between older adult and younger adult patients. Since fluconazole is primarily cleared renally and geriatric patients are more likely to have decreased renal function , care should be taken to adjust dose based on creatinine clearance. It may also be useful to monitor renal function. Systemic fluconazole can prolong the QT interval. Geriatric patients may be at increased risk for QT prolongation and for serious drug-drug interactions that may increase the risk QT prolongation risk or may increase the risk for other serious side effects. The federal Omnibus Budget Reconciliation Act (OBRA) regulates medication use in residents of long-term care facilities (LTCFs). According to OBRA, systemic azole antifungals should be used in the lowest possible dose for the shortest possible duration, particularly in patients receiving other medications known to interact with these medications. Increased monitoring may be required to identify and minimize the toxicity of warfarin, phenytoin, theophylline, or sulfonylureas when an azole antifungal is co-administered; other medications such as rifampin and cimetidine may decrease the therapeutic effect of the antifungal. Some drug-drug combinations may be contraindicated. OBRA guidelines caution that azole antifungals may cause hepatotoxicity, headaches, and GI distress.
How long does it take to get rid of cryptococcal meningitis?
The recommended duration of treatment for initial therapy of cryptococcal meningitis is 10 to 12 weeks after the cerebrospinal fluid becomes culture negative.
How long does esophageal candidiasis last?
Patients with esophageal candidiasis should be treated for a minimum of three weeks and for at least 2 weeks following the resolution of symptoms.
How to mix fluconazole suspension?
Prepare a suspension at time of dispensing as follows: tap bottle until all the powder flows freely. To reconstitute, add 24 mL of distilled water or Purified Water (USP) to fluconazole bottle and shake vigorously to suspend powder. Each bottle will deliver 35 mL of suspension.
How much a day for peritonitis?
Urinary tract infections and peritonitis. For the treatment of Candida urinary tract infections and peritonitis, daily doses of 50 to 200 mg have been used in open, noncomparative studies of small numbers of patients.
Can you take Diflucan for candidiasis?
The daily dose of DIFLUCAN for the treatment of infections other than vaginal candidiasis should be based on the infecting organism and the patient's response to therapy. Treatment should be continued until clinical parameters or laboratory tests indicate that active fungal infection has subsided.
Is fluconazole the same as oral absorption?
SINCE ORAL ABSORPTION IS RAPID AND ALMOST COMPLETE, THE DAILY DOSE OF DIFLUCAN (FLUCONAZOLE) IS THE SAME FOR ORAL (TABLETS AND SUSPENSION) AND INTRAVENOUS ADMINISTRATION. In general, a loading dose of twice the daily dose is recommended on the first day of therapy to result in plasma concentrations close to steady-state by the second day of therapy.
Is fluconazole cleared by renal excretion?
Fluconazole is cleared primarily by renal excretion as unchanged drug. There is no need to adjust single dose therapy for vaginal candidiasis because of impaired renal function. In patients with impaired renal function who will receive multiple doses of DIFLUCAN, an initial loading dose of 50 mg to 400 mg should be given. After the loading dose, the daily dose (according to indication) should be based on the following table:
How long does it take for granulocytopenia to start?
Patients who are anticipated to have severe granulocytopenia should start prophylaxis several days before anticipated onset of neutropenia and continue for 7 days after neutrophil count rises >1000 cells per mm³
Can fluconazole be used during pregnancy?
Use in pregnancy should be avoided except in patients with severe or potentially life-threatening fungal infections in whom fluconazole may be used if the anticipated benefit outweighs the possible risk to the fetus
Is Candida krusei resistant to fluconazole?
Candida krusei is inherently resistant. Convenience and efficacy of single dose oral tablet of fluconazole regimen for the treatment of vaginal yeast infections should be weighed against acceptability of higher incidence of drug related adverse events with fluconazole (26%) versus intravaginal agents (16%)
Does sucrose powder cause headaches?
Powder for oral suspension contains sucrose and should not be used in patients with hereditary fructose, glucose/galactose malabsorption or sucrase-isomaltase deficiency. Syrup contains glycerol; may cause headache, stomach upset, and diarrhea.
How long does itraconazole last for tinea pedis?
Tinea pedis has been effectively treated with pulse doses of 150 mg fluconazole once weekly, with 100 mg itraconazole daily for 2 weeks or 400 mg daily for 1 week, and with 250 mg terbinafine daily for 2 weeks.
How long does itraconazole treatment last?
Tinea corporis and tinea cruris were effectively treated by 50 to 100 mg fluconazole daily or 150 mg once weekly for 2 to 3 weeks, by 100 mg itraconazole daily for 2 weeks or 200 mg daily for 7 days, and by 250 mg terbinafine daily for 1 to 2 weeks.
How long does idsa last?
IDSA Recommendations:#N#Mild to moderate pulmonary infection and nonmeningeal, nonpulmonary infection if CNS disease ruled out, no fungemia, single site of infection, no immunosuppressive risk factors: 400 mg orally once a day for 6 to 12 months#N#Severe pulmonary infection and nonmeningeal, nonpulmonary infection with cryptococcemia:#N#-Consolidation therapy (after induction therapy): 400 to 800 mg orally once a day for at least 8 weeks#N#-Maintenance therapy: 200 to 400 mg orally once a day for 12 months#N#Comments:#N#-Preferred agent#N#-Maintenance therapy is recommended to prevent relapse.#N#-Primary prophylaxis not routinely recommended.#N#US CDC, NIH, and IDSA Recommendations for HIV-infected Patients:#N#Non-CNS cryptococcosis with mild to moderate symptoms and focal pulmonary infiltrates: 400 mg orally once a day for 12 months#N#Non-CNS, extrapulmonary cryptococcosis and diffuse pulmonary disease:#N#-Induction therapy: 400 to 1200 mg IV or orally once a day for at least 2 weeks#N#-Consolidation therapy (after at least 2 weeks successful induction therapy): 400 mg IV or orally once a day for at least 8 weeks#N#-Maintenance therapy: 200 mg orally once a day for at least 1 year#N#Comments:#N#-Recommended for use in alternative regimens for induction therapy; dose depends on regimen (i.e., used with amphotericin B, flucytosine, or alone).#N#-Recommended as preferred regimen for consolidation therapy; should be followed by maintenance therapy#N#-Recommended as preferred regimen for maintenance therapy
How long does fluconazole last?
200 mg IV or orally on the first day followed by 100 mg IV or orally once a day#N#Duration of therapy: At least 3 weeks and for at least 2 weeks after symptoms resolve#N#Comments:#N#-Doses up to 400 mg/day may be used based on clinical judgment of patient response.#N#IDSA Recommendations: 200 to 400 mg IV or orally once a day for 14 to 21 days#N#Comments:#N#-Recommended as primary therapy; oral fluconazole is preferred.#N#US CDC, NIH, and IDSA Recommendations for HIV-infected Patients: 100 to 400 mg IV or orally once a day for 14 to 21 days#N#-Suppressive therapy: 100 to 200 mg orally once a day#N#Comments:#N#-Recommended as preferred therapy#N#-Unless frequent or severe recurrences, suppressive therapy generally not recommended
How long does it take for a cutaneous infection to resolve?
IDSA Recommendations:#N#Cutaneous or lymphocutaneous infection: 400 to 800 mg IV or orally once a day#N#Duration of therapy: 2 to 4 weeks after all lesions resolve (usually 3 to 6 months total)#N#Comments:#N#-Recommended as alternative therapy; should only be used if other agents are not tolerated
How long does oral thrush treatment last?
Oropharyngeal candidiasis: 200 mg IV or orally on the first day followed by 100 mg IV or orally once a day. Duration of therapy: At least 2 weeks, to reduce the risk of relapse. IDSA Recommendations:
How long does 400 mg IV last?
Acute infection: 400 mg IV or orally on the first day followed by 200 mg IV or orally once a day#N#Duration of therapy: 10 to 12 weeks after CSF culture is negative#N#Comments:#N#-Dose of 400 mg IV or orally once a day may be used based on clinical judgment of patient response.#N#IDSA Recommendations:#N#-Consolidation therapy (after induction therapy): 400 to 800 mg orally once a day for 8 weeks#N#-Maintenance therapy: 200 mg orally once a day for 6 to 12 months#N#Comments:#N#-Preferred agent#N#-The higher dose (800 mg/day) is recommended for consolidation therapy if the 2-week induction regimen was used.#N#-Maintenance therapy is recommended to prevent relapse.#N#Cerebral cryptococcoma:#N#-Consolidation and maintenance therapy (after induction therapy): 400 to 800 mg orally once a day for 6 to 18 months