What to know about ondansetron before taking it?
09/05/2020 · Ondansetron is an anti-nausea medication and promethazine is a phenothiazine. Side effects of ondansetron and promethazine that are similar include drowsiness and sedation, constipation, and dizziness.
What should I avoid while taking ondansetron?
22/06/2020 · SIDE EFFECTS: Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Likewise, is Zofran a sedating?
What is Zofran (ondansetron)?
05/08/2021 · The more common side effects of ondansetron can include: headache. diarrhea. constipation. dizziness. drowsiness. If these effects are mild, they may go away within a few days or a couple of weeks ...
Does Zofran make you tired or sleepy?
Yes, from personal experience, Zofran can make you sleepy. I have taken Zofran in the past, and in the beginning when I first started taking it, about the first couple of weeks, it made me sleepy. After that though the sleepiness side effect wore off and I was no longer sleepy when I took it. So to answer your question, yes, Zofran can make you sleepy. However, YMMV.
How long does it take for ondansetron to kick in?
Ondansetron should start to work within 30 minutes to an hour. Ondansetron tablets are available in two different forms – tablets or oral disintegrating tablets (also called ODT). Tablets: swallow the tablets with a glass of water. Do not halve or crush the tablets.05-Dec-2021
What are side effects of ondansetron?
Ondansetron may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:headache.constipation.weakness.tiredness.chills.drowsiness.
Will 4mg of Zofran make you sleepy?
Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
Does Zofran make you sleepy like Phenergan?
Zofran is an antiemetic (anti-nausea and vomiting) and selective 5-HT3 receptor antagonist and Phenergan is an antihistamine. Side effects of Zofran and Phenergan that are similar include dizziness, drowsiness, constipation, and blurred vision.
Does metoclopramide make you drowsy?
Metoclopramide oral tablet may cause drowsiness. Some people may have dizziness, nervousness, or headaches after they stop taking this drug. It can also cause other side effects.
Does Zofran cause sleeplessness?
SIDE EFFECTS: Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly.
Why does nausea medicine make you sleepy?
Drugs that control nausea, keep you from throwing up, or treat diarrhea can make you sleepy. Muscle relaxants. Most muscle relaxants don't work on your muscles directly. Instead, they work on the nerves in your brain and spine to make the muscles relax.29-Nov-2021
Does anti-nausea medication make you sleepy?
It can make you sleepy, so talk to your doctor about the side effects you might have while using olanzapine. Combination anti-nausea medicines include more than one type of anti-nausea drug in one dose. For example, you can get a combination of a serotonin (5-HT3) antagonist with a NK-1 receptor antagonist.12-Mar-2021
How do you sleep with nausea?
Prop your head up so you're not lying flat in bed. If it's comfortable for you, try to sleep with your head about 12 inches above your feet. This can help keep acid or food from moving up into your esophagus. Drink a small amount of a slightly sweet liquid, like fruit juice, but avoid citrus.
Does Zofran calm you down?
Conclusions: Ondansetron has been shown to be an effective treatment for early-onset alcoholism. Ondansetron's ability to improve symptoms of depression, anxiety, and hostility among EOA may make an additional contribution to its therapeutic effect.
What is the strongest nausea medicine?
Best anti-nausea medicationsBest anti-nausea medicationsMedicationOTC or RxSingleCare couponZofran (ondansetron)RxGet CouponPromethegan (promethazine)RxGet CouponPhenergan (promethazine)RxGet Coupon10 more rows
Which is better Phenergan or Zofran?
Zofran (ondansetron) works well to prevent nausea and vomiting. It's available in different forms that you don't have to swallow in case you can't keep anything down. Helps you feel less queasy. Phenergan (Promethazine) is used to treat and prevent nausea and vomiting from surgery, motion sickness, or pregnancy.
What are the problems with the liver?
People with liver problems. People with a blockage in the gut (intestinal obstruction). People with heart problems involving the conduction of the electrical signals in the heart, such as a slow heartbeat, sick sinus syndrome, heart block or an irregular heartbeat.
How to stop nausea and vomiting?
Instead try eating small nourishing snacks throughout the day. You should also try to sip water regularly to help avoid dehydration.
Can you take Ondansetron while pregnant?
Make sure you let your doctor know if you are or think you could be pregnant before taking ondansetron. The safety of using ondansetron in pregnancy has not been well established and it's not usually recommended for use in pregnant women, unless the potential benefit outweighs any risks to the developing baby.
Can Ondansetron be used for pregnancy?
Ondansetron is generally only prescribed for pregnancy sickness if other treatments have not worked. You can get further information from your doctor. Ondansetron may pass into breast milk in small amounts and is not usually recommended for women who are breastfeeding. Ask your doctor for more information and advice.
What medications affect serotonin?
other medications that affect serotonin, such as amphetamines, fentanyl, tramadol, trip tans (eg, almotriptan, eletriptan, or sumatriptan), or St. John's Wort. Note that this list is not all-inclusive and includes only common medications that may interact with ondansetron.
How does Ondansetron work?
Ondansetron treats and prevents nausea and vomiting by an unknown mechanism, possibly by a direct effect on the CTZ (the area of the brain associated with vomiting), the vagus nerve, or both. The neurotransmitter, serotonin, appears to play a role in ondansetron's effect.
Is Ondansetron a 5-HT3 antagonist?
Ondansetron belongs to the class of medicines known as 5-HT3 receptor antagonists. 2. Upsides. Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy.
Is Ondansetron a liquid?
Oral ondansetron is available as a conventional tablet, orally disintegrating tablet, or an oral solution. Oral disintegrating tablets are not required to be administered with liquid. Generic ondansetron is available. 3.
Can Ondansetron cause headaches?
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. 5. Tips. May be taken with or without food. Take oral tablets with a big glass of water. Consider taking laxatives at the same time as ondansetron to prevent or relieve constipation.
Can you drive while taking Ondansetron?
If ondansetron makes you dizzy or drowsy, do not drive or operate machinery while you are affected and avoid alcohol. Tell your doctor or pharmacist about any other medications you are taking, and do not take other medications without first checking to see if they are compatible with ondansetron. 6.
What are the side effects of taking a syringe?
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Tiredness, a headache, drowsiness, dizziness, constipation, flushing, itching, slowed heart rate, raised body temperature, itchy skin, or diarrhea.
What to do before using Ondansetron?
Therefore, before using ondansetron, report all medications you are currently using to your doctor or pharmacist.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.
How to prevent nausea after radiation?
To prevent nausea from radiation treatment, take this medication by mouth 1 to 2 hours before the start of your treatment. To prevent nausea after surgery, take ondansetron by mouth 1 hour before the start of surgery. This medication may be taken with or without food.
Where to report side effects of Ondansetron?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. See more info: ondansetron-oral on RxList. Selected from data included with permission and copyrighted by First Databank, Inc.
Can you take Ondansetron if you are allergic to it?
PRECAUTIONS: Before taking ondansetron, tell your doctor or pharmacist if you are allergic to it; or to other serotonin blockers (e.g., granisetron ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Can Ondansetron make you dizzy?
Talk to your doctor about using ondansetron safely.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
What is Zofran used for?
BRAND NAME (S): Zofran. USES: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment ( chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.
How to contact poison control center?
US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. NOTES: Do not share this product with others.Laboratory and/or medical tests (such as EKG) should be performed periodically to monitor your progress or check for side effects.
What is Zofran used for?
Zofran is a brand (trade) name for ondansetron which may be used to treat or prevent nausea and vomiting. Experts aren't sure exactly how Zofran (ondansetron) works and if its antiemetic action is mediated by a direct effect on the CTZ (the area of the brain associated with vomiting), the vagus nerve, or both.
How long after chemo do you give 8mg?
For moderately emetogenic chemotherapy, an 8mg dose administered 30 minutes before the start of chemotherapy with a subsequent 8mg dose administered 8 hours after the first dose. Then administer twice a day for 1 to 2 days after completion of the chemotherapy. May be given to children aged 4 and older.
When to take Zofran before surgery?
When used to prevent nausea associated with surgery, Zofran is usually taken one hour before anesthesia. The dose of Zofran orally disintegrating tablets is the same as Zofran solution. When taking the orally disintegrating tablets, peel back the foil (do not attempt to push the tablet through the foil).
Is Zofran a dopamine receptor antagonist?
Zofran is not a dopamine‑receptor antagonist. Zofran belongs to the class of medicines known as 5-HT3 receptor antagonists. 2. Upsides. Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy.
What to do if Zofran makes you dizzy?
If Zofran makes you dizzy or drowsy, do not drive or operate machinery while affected and avoid alcohol. Tell your doctor or other health care provider about all the medicines you take, including prescription and over-the-counter (OTC) medicines, vitamins, and herbal supplements.
Is Zofran an oral solution?
Zofran is available as tablets, orally disintegrating tablets, and an oral solution. Tablets and orally disintegrating tablets are available in 4mg and 8mg strengths. Zofran oral solution is 4mg/5mL with a strawberry odor.
What medications affect serotonin?
other medications that affect serotonin, such as amphetamines, fentanyl, tramadol, triptans ( eg, almotriptan, eletriptan, or sumatriptan), or St. John's Wort . Note that this list is not all-inclusive and includes only common medications that may interact with Zofran.
How It Works
- Ondansetron treats and prevents nausea and vomiting by an unknown mechanism, possibly by a direct effect on the CTZ (the area of the brain associated with vomiting), the vagus nerve, or both. The n...
- Ondansetron belongs to the class of medicines known as 5-HT3 receptor antagonists.
Upsides
- Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy.
- May also be used to prevent nausea and vomiting associated with radiotherapy - this includes total body irradiation or single or multiple high-dose or daily fractions to the abdomen.
- Effective at preventing postoperative nausea and vomiting. Not recommended for routine pro…
- Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy.
- May also be used to prevent nausea and vomiting associated with radiotherapy - this includes total body irradiation or single or multiple high-dose or daily fractions to the abdomen.
- Effective at preventing postoperative nausea and vomiting. Not recommended for routine prophylaxis, especially if there is little expectation that nausea or vomiting will occur; however, can be giv...
- May be administered orally, by IV infusion, or by IV or IM injection. IV infusions should be infused over 15 minutes and injections pushed over at least 30 seconds, but preferably 2 to 5 minutes. M...
Downsides
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. Tiredness, a headache, drowsiness, dizziness, constipation, flushing, itching, slowed heart rate, raised body temperature, itchy skin, or diarrhea. 2. Rarely may cause hiccups, blurred vision or vision loss, a rash, or liver d…
Bottom Line
- Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache.
Tips
- May be taken with or without food. Take oral tablets with a big glass of water.
- Consider taking laxatives at the same time as ondansetron to prevent or relieve constipation.
- When taking orally disintegrating ondansetron tablets, peel back the foil (do not attempt to push the tablet through the foil). Allow the tablet to dissolve in your mouth without chewing.
- When taking the oral soluble strip film, use dry hands to remove the strip and place it on your …
- May be taken with or without food. Take oral tablets with a big glass of water.
- Consider taking laxatives at the same time as ondansetron to prevent or relieve constipation.
- When taking orally disintegrating ondansetron tablets, peel back the foil (do not attempt to push the tablet through the foil). Allow the tablet to dissolve in your mouth without chewing.
- When taking the oral soluble strip film, use dry hands to remove the strip and place it on your tongue. Leave to dissolve without chewing. Swallow several times after the strip dissolves. A glass o...
Response and Effectiveness
- The peak effect of ondansetron is seen within 1.5-2 hours. The onset of the effect is faster with the wafer form of ondansetron.
Interactions
- Medicines that interact with ondansetron may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with ondansetron. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions sh…
Further Information
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use ondansetron only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright 1996-2022 Drugs.com. Revision date: March 16, 2021. Medical Disclai…
How It Works
- Zofran is a brand (trade) name for ondansetron which may be used to treat or prevent nausea and vomiting.
- Experts aren't sure exactly how Zofran (ondansetron) works and if its antiemetic action is mediated by a direct effect on the CTZ (the area of the brain associated with vomiting), the vagus nerve,...
- Zofran is a brand (trade) name for ondansetron which may be used to treat or prevent nausea and vomiting.
- Experts aren't sure exactly how Zofran (ondansetron) works and if its antiemetic action is mediated by a direct effect on the CTZ (the area of the brain associated with vomiting), the vagus nerve,...
- Zofran belongs to the class of medicines known as 5-HT3 receptor antagonists.
Upsides
- Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy.
- May also be used to prevent nausea and vomiting associated with radiotherapy - this includes total body irradiation or single or multiple high-dose or daily fractions to the abdomen. The usual dosa...
- Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy.
- May also be used to prevent nausea and vomiting associated with radiotherapy - this includes total body irradiation or single or multiple high-dose or daily fractions to the abdomen. The usual dosa...
- Effective at preventing postoperative nausea and vomiting. The usual dosage is 16mg administered 1 hour before the induction of anesthesia.
- Zofran is available as tablets, orally disintegrating tablets, and an oral solution. Tablets and orally disintegrating tablets are available in 4mg and 8mg strengths. Zofran oral solution is 4mg/5m...
Downsides
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. A headache, hypoxia (low oxygen), fever, dizziness, gynecological disorders, anxiety or agitation, urinary retention, and itching are the most common side effects reported. 2. Rarely may cause hiccups, flushing, blurr…
Bottom Line
- Zofran may be used for the treatment and prevention of nausea and vomiting caused by cancer chemotherapy, radiation, or surgery. It is approved for use in children over the age of 4, and a headache...
Tips
- Take as directed. May be taken with or without food.
- When used to prevent nausea associated with chemotherapy, Zofran is usually taken 30 minutes before chemotherapy. When used to prevent nausea associated with radiotherapy, Zofran is usually taken o...
- The dose of Zofran orally disintegrating tablets is the same as Zofran solution.
- Take as directed. May be taken with or without food.
- When used to prevent nausea associated with chemotherapy, Zofran is usually taken 30 minutes before chemotherapy. When used to prevent nausea associated with radiotherapy, Zofran is usually taken o...
- The dose of Zofran orally disintegrating tablets is the same as Zofran solution.
- When taking the orally disintegrating tablets, peel back the foil (do not attempt to push the tablet through the foil). Allow the tablet to dissolve in your mouth without chewing.
Response and Effectiveness
- The peak effect of Zofran is reached within 1.5-2 hours. The onset of effect is faster with the orally disintegrating or liquid form.
- In one trial of patients receiving highly emetogenic cancer chemotherapy, 66% of patients receiving ondansetron 24mg as a single dose, 55% of patients receiving ondansetron 8mg every 8 hours for tw...
- The peak effect of Zofran is reached within 1.5-2 hours. The onset of effect is faster with the orally disintegrating or liquid form.
- In one trial of patients receiving highly emetogenic cancer chemotherapy, 66% of patients receiving ondansetron 24mg as a single dose, 55% of patients receiving ondansetron 8mg every 8 hours for tw...
- For other indications, such as postoperative nausea and vomiting, Zofran was significantly more effective than placebo (an inactive medicine).
Interactions
- Medicines that interact with Zofran may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Zofran. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be mana…
References
- Zofran (ondansetron). Revised 09/2020. GlaxoSmithKline LLC https://www.drugs.com/pro/zofran.html#s-34090-1
Further Information
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Zofran only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright 1996-2022 Drugs.com. Revision date: February 19, 2021. Medical Disc…