Precautions
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Why is Carafate so expensive?
Sucralfate (Carafate) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Does Carafate interact with other medications?
Carafate is an anti-ulcer medication. Carafate is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by sticking to ulcer sites and protecting them from acids, enzymes, and bile salts.
Is Carafate a narcotic medication?
teaspoonfuls) four times per day. CARAFATE should be administered on an empty stomach. Antacids may be prescribed as needed for relief of pain but should not be taken within one-half hour before or after sucralfate. While healing with sucralfate may occur during the first week or two, treatment should be continued for
When should Carafate be administered?
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What is the drug Carafate used for?
This medication is used to treat and prevent ulcers in the intestines. Sucralfate forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal more quickly.
Is Carafate used for acid reflux?
Carafate (sucralfate) and omeprazole are used to treat ulcers and gastroesophageal reflux disease (GERD).
How long does it take for Carafate to work?
It may take 2 to 8 weeks before you receive the full benefit of taking Carafate. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Your doctor may want you to keep taking Carafate at a lower dose once your active ulcer has healed.
What symptoms does Carafate help?
What Conditions does CARAFATE Treat?reflux esophagitis, or inflammation of the esophagus from backflow of stomach acid.gastroesophageal reflux disease.a stomach ulcer.medication treatment for healing stomach ulcer.an ulcer of the duodenum.medication treatment for healing ulcer of the duodenum.stress ulcer prevention.More items...
Is Carafate better than omeprazole?
Omeprazole was significantly superior to sucralfate in inducing gastric ulcer healing after both 4 (87 vs. 52%, P = 0.007) and 8 weeks (100 vs. 82%, P = 0.04). No statistically significant difference in duodenal ulcer healing rates emerged between the two groups either at 4 (79 vs.
Does Carafate heal the esophagus?
It is concluded that treatment with sucralfate improves the symptomatology and severity of reflux esophagitis. The results obtained with sucralfate appear comparable to those with cimetidine. Sucralfate may therefore be considered as a valid alternative to H2-receptor antagonist therapy in treating reflux esophagitis.
How long does Carafate coat the stomach?
The sucralfate-albumin film provides a barrier to diffusion of hydrogen ions. In human subjects, Sucralfate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%. One dose lasts approximately 6 hours. It may take up to eight weeks before an ulcer is fully healed.
Does Carafate make you sleepy?
itching, rash; dizziness, drowsiness; sleep problems (insomnia);
Does Carafate help gastritis?
Sucralfate is the primary agent for prophylaxis of stress gastritis. It has long been used as a means of decreasing the incidence of gastritis. This drug is readily available, easy to administer, and inexpensive.
Can you drink water with Carafate?
Pharmacist tips for sucralfate (Carafate) Take sucralfate (Carafate) on an empty stomach with plenty of water. This will help the medication work quickly at the site of the ulcer.
Can you drink coffee with Carafate?
Do not take antacids (e.g. Mylanta) 30 minutes before or after taking sucralfate. Avoid foods and drinks that may upset your stomach such as alcohol, citrus fruits and juices, drinks containing caffeine, tomatoes, or spicy food - as these may delay healing of the stomach/duodenal ulcers.
What is the most common side effect of sucralfate?
Constipation. The most common side effect of sucralfate is constipation. The medication works by binding to ulcers to protect them from further exposure to stomach acid, bile, pepsin, and bile salts. This gives the ulcers time to heal.
Can I take omeprazole and Carafate at the same time?
Many people with ulcers will also be prescribed other medications to lower the amount of acid in their stomach. Since sucralfate (Carafate) can affect the way medication is absorbed, most medications including omeprazole (Prilosec) should be separated from sucralfate (Carafate) by 30 minutes to an hour.
Is sucralfate like Pepto Bismol?
Pepto-Bismol (bismuth subsalicylate) Carafate (sucralfate) has few side-effects, but is more expensive than other medicines used to treat ulcers. Relieves heartburn, upset stomach, and diarrhea.
Is there an over the counter medicine similar to Carafate?
There is nothing similar to carafate available over the counter (OTC). Carafate is an anti-ulcer medication that works by forming a complex that covers the ulcer site, which protects it from acid, so that it can heal.
Does sucralfate work immediately?
It may take up to eight weeks before an ulcer is fully healed. Each 1g dose of sucralfate neutralizes approximately 14 to 16 mEq of stomach acid.
What Do I Need to Tell My Doctor Before I Take Carafate?
1. If you have an allergy to sucralfate or any other part of Carafate (sucralfate tablets). 2. If you are allergic to any drugs like this one, any...
What Are Some Things I Need to Know Or Do While I Take Carafate?
1. Tell all of your health care providers that you take Carafate (sucralfate tablets). This includes your doctors, nurses, pharmacists, and dentist...
How Is This Medicine (Carafate) Best Taken?
Use Carafate (sucralfate tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. Take on an empt...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Carafate?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Carafate?
1. Store at room temperature. 2. Store in a dry place. Do not store in a bathroom. 3. Keep all drugs in a safe place. Keep all drugs out of the rea...
Before Taking This Medicine
You should not use Carafate if you are allergic to sucralfate.To make sure Carafate is safe for you, tell your doctor if you have: 1. diabetes; 2....
How Should I Take Carafate?
Take Carafate exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smalle...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember, but avoid taking any other medications within 2 hours before or after you take Carafate. Skip the mis...
What Other Drugs Will Affect Carafate?
Carafate can make it harder for your body to absorb other medications you take by mouth. Avoid taking any other medications within 2 hours before o...
How should I take Carafate?
Take Carafate exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
How long does it take to get the full benefit of carafate?
Carafate oral suspension is to be taken only by mouth. It may take 2 to 8 weeks before you receive the full benefit of taking Carafate.
What other drugs will affect Carafate?
Other drugs may interact with sucralfate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
What is the purpose of sucralfate?
It works mainly in the lining of the stomach by sticking to ulcer sites and protecting them from acids, enzymes, and bile salts. Carafate is used to treat an active duodenal ulcer.
How long before taking carafate can you take other medications?
Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Avoid taking any other medications within 2 hours before or after you take Carafate.
Can carafate be used for duodenal ulcers?
Carafate is used to treat an active duodenal ulcer. Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring.
Can you share Carafate with children?
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Carafate only for the indication prescribed.
What is carafate used for?
Carafate is a prescription medicine used to treat the symptoms of Duodenal Ulcer. Carafate may be used alone or with other medications.
What are the side effects of carafate?
The most common side effects of Carafate include: constipation, diarrhea, nausea, vomiting, upset stomach,
How is sucralfate absorbed?
Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. The following observations also appear pertinent: 1 Studies in human subjects and with animal models of ulcer disease have shown that sucralfate forms an ulcer-adherent complex with proteinaceous exudate at the ulcer site. 2 In vitro, a sucralfate- albumin film provides a barrier to diffusion of hydrogen ions. 3 In human subjects, sucralfate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%.
How to report carafate side effects?
These are not all the possible side effects of Carafate. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the purpose of sucralfate albumin film?
In vitro, a sucralfate- albumin film provides a barrier to diffusion of hydrogen ions.
Does sucralfate help with duodenal ulcers?
While short-term treatment with sucralfate can result in complete healing of the ulcer, a successful course of treatment with sucralfate should not be expected to alter the post healing frequency or severity of duodenal ulceration. Episodes of hyperglycemia have been reported in diabetic patients.
Does sucralfate reduce absorption?
Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin , fluoroquinolone antibiotics, ketoconazole, l- thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline.
Where is carafate absorbed?
Carafate Tablets - Clinical Pharmacology. Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine.
How long does sucralfate last?
CARAFATE® (sucralfate) is indicated in: 1 Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination. 2 Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.
How long does it take for antacids to heal after sucralfate?
Antacids may be prescribed as needed for relief of pain but should not be taken within one-half hour before or after sucralfate. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.
How long after meals can you take sucralfate?
The poorer result in the first study may have occurred because sucralfate was given 2 hours after meals and at bedtime rather than 1 hour before meals and at bedtime, the regimen used in international studies and in the second United States study. In addition, in the first study liquid antacid was utilized as needed, whereas in the second study antacid tablets were used.
Does sucralfate inhibit pepsin?
3. In human subjects, sucralfate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%.
Does sucralfate reduce absorption?
Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline.
Does sucralfate form an ulcer-adherent complex?
1. Studies in human subjects and with animal models of ulcer disease have shown that sucralfate forms an ulcer-adherent complex with proteinaceous exudate at the ulcer site. 2. In vitro, a sucralfate-albumin film provides a barrier to diffusion of hydrogen ions. 3.
Frequently asked questions
Can you buy something like carafate over the counter without a prescription?
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
What is the color of the pill CARAFATE?
This medicine is a light pink, oblong, scored, tablet imprinted with "CARAFATE" and "17 12".
What is sucralfate used for?
This medication is used to treat and prevent ulcers in the intestines. Sucralfate forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal more quickly.
How long does sucralfate last?
Inform your doctor if your condition persists or worsens after you have been taking sucralfate for 4 weeks. Side Effects. Constipation, dry mouth, upset stomach, gas, and nausea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
How to report sucralfate side effects in Canada?
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking sucralfate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Can you take sucralfate while pregnant?
If you are pregnant, tell your doctor before using sucralfate. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects.
Is First Databank copyrighted?
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
Are you currently using Carafate oral?
This survey is being conducted by the WebMD marketing sciences department.
What is nitrofurantoin used for?
Nitrofurantoin is an antibiotic made use of for treatment and prevention of urinary system infections (e.g., acute cystitis, urethritis) and those triggered by urologic surgical treatment or evaluation (cystoscopy, catheterization).
Can you take Florinef with sucralfate?
Three of the active-controlled research studies are described here. Take Florinef by mouth with or without food. Do not combine Prevacid with sucralfate, as an unpleasant impact is feasible. Carafate is not significantly soaked up right into the body through the digestion system.
What is the reaction of sucralfate?
Sucralfate reacts with hydrochloric acid in the stomach to form an adherent, paste-like substance capable of acting as an acid buffer. Subsequently, sucralfate adheres electrostatically to proteins on the surface of an ulcer, such as albumin and fibrinogen, forming insoluble, stable complexes.
How much aluminum is in sucralfate?
Small amounts of aluminum can be absorbed following oral administration of sucralfate. Each 1 g tablet contains roughly 207 mg of aluminum. Sucralfate should not be given concomitantly with other agents containing aluminum (e.g., aluminum-containing antacids) because the total body burden of aluminum can increase.
How long before sucralfate can you take antacids?
Antacids should not be administered within 30 minutes of sucralfate. (Minor) Proton pump inhibitors should be taken at least 30 minutes prior to sucralfate. Sucralfate has been shown to delay absorption and reduce the bioavailability of omeprazole by about 16%.
How long after taking sucralfate can I take dolutegravir?
Dolutegravir: (Moderate) Administer dolutegravir 2 hours before or 6 hours after taking sucralfate. The chemical structure of sucralfate contains aluminum, which can bind dolutegravir in the GI tract. Taking these drugs simultaneously may result in reduced bioavailability of dolutegravir.
How long after sucralfate can I take abacavir?
Abacavir; Dolutegravir; Lamivudine: (Moderate) Administer dolutegravir 2 hours before or 6 hours after taking sucralfate. The chemical structure of sucralfate contains aluminum, which can bind dolutegravir in the GI tract. Taking these drugs simultaneously may result in reduced bioavailability of dolutegravir.
How long after oral alendronate can you take sucralfate?
Separation of administration is advised. At least 30 minutes should elapse after an alendronate dose before taking aluminum-containing drugs.
Is sucralfate absorbed in breast milk?
Because only small portions of sucralfate are absorbed systemically in the mother, and virtually no excretion is expected into breast milk, sucralfate is considered to be compatible with breast-feeding by the American College of Gastroenterology.
How long before sucralfate to take?
Drug interactions of Carafate may include reactions with other drugs taken at the same time, preventing their full absorption. It is best to take other drugs 2 hours before or after sucralfate to avoid drug interactions.
Does sucralfate cause bezoars?
Cases of hyperglycemia have been reported with sucralfate. Bezoars have been reported in patients treated with sucralfate. The majority of patients had underlying medical conditions that may predispose to bezoar formation (such as delayed gastric emptying) or were receiving concomitant enteral tube feedings.
Does sucralfate cause lip swelling?
Post-marketing cases of hypersensitivity have been reported with the use of sucralfate oral suspension, including anaphylactic reactions, dyspnea, lip swelling, edema of the mouth, pharyngeal edema, pruritus, rash, swelling of the face and urticaria. Cases of bronchospasm, laryngeal edema and respiratory tract edema have been reported with an unknown oral formulation of sucralfate.
Can you get pregnant with carafate?
Tell your doctor if you are pregnant or plan to become pregnant during treatment with Carafate. Carafate is not expected to be harmful to a fetus. It is unknown if Carafate passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
Is carafate a tablet?
Dosage for Carafate. Carafate is administered orally in the form of tablets. Lower than usual dosages are recommended for elderly patients and adolescents.
Frequently asked questions
Can you buy something like carafate over the counter without a prescription?
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Description
This medication is used to treat and prevent ulcers in the intestines.
May Treat: Duodenal ulcer · Gastroesophageal reflux disease · Maintenance of healing duodenal ulcer
Drug Class: Peptic Ulcer - Gastric Lumen Adherent Cytoprotectives
Availability: Prescription Required
Pregnancy: Consult your doctor
Lactation: Consult a doctor before using
May Treat: Duodenal ulcer · Gastroesophageal reflux disease · Maintenance of healing duodenal ulcer
Drug Class: Peptic Ulcer - Gastric Lumen Adherent Cytoprotectives
Availability: Prescription Required
Pregnancy: Consult your doctor
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: SANOFI-AVENTIS
- Take on an empty stomach
- Take doses regularly, even when feeling well
- Do not stop medicine without calling doctor
- Take on an empty stomach
- Take doses regularly, even when feeling well
- Do not stop medicine without calling doctor
- Do not take antacids within 1/2 hour
- Call MD or RPh re. timing of taking with other meds
- Review all drugs you are taking with your doctor
- May take 8 weeks for full benefit of therapy
- For suspension, oral products : Shake well & measure with dosing spoon/cup/syringe.
- For tablet products : Take at the same time every day.
Carafate Tablets - Clinical Pharmacology
Clinical Trials
Indications and Usage
Contraindications
Precautions
- Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. Although the mechanism of sucralfate’s ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. The following observations also appear pertinent: 1. Studies in human subject…
Adverse Reactions
- Acute Duodenal Ulcer Over 600 patients have participated in well-controlled clinical trials worldwide. Multicenter trials conducted in the United States, both of them placebo-controlled studies with endoscopic evaluation at 2 and 4 weeks, showed: The sucralfate-placebo differences were statistically significant in both studies at 4 weeks but not at 2 weeks. The poorer result in the first study may have occurred because sucralfate was given 2 hours afte…
Overdosage
- CARAFATE®(sucralfate) is indicated in: 1. Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination. 2. Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.
Dosage and Administration
- Carafate is contraindicated in patients with known hypersensitivity reactions to the active substance or to any of the excipients.
How Supplied
- The physician should read the “PRECAUTIONS” section when considering the use of this drug in pregnant or pediatric patients, or patients of childbearing potential. Duodenal ulcer is a chronic, recurrent disease. While short-term treatment with sucralfate can result in complete healing of the ulcer, a successful course of treatment with sucralfate should not be expected to alter the post healing frequency or severity of duodenal ulceration. Isolate…