Bacteriostatic Water (bacteriostatic water for injection) is sterile water containing 0.9% benzyl alcohol that is used to dilute or dissolve medications; the container can be reentered multiple times (usually by a sterile needle) and the benzyl alcohol suppresses or stops the growth of most potentially contaminating bacteria.
What is bacteriostatic water?
What is Bacteriostatic Water? Bacteriostatic Water for Injection is sterile, non-pyrogenic water that contains 0.9% benzyl alcohol (9mg/mL) added as a bacteriostatic preservative. This preparation of sterile water and benzyl alcohol (BnOH) allows repeated withdrawals to be made from a single 30mL plastic vial.
How to prepare bacteriostatic water for injection?
1.Remove protective cap. 2.Cleanse stopper with suitable germicide. 3.Aseptically add 1 mL Bacteriostatic Water for Injection, USP (with benzyl alcohol) for the 40 mg vial or 2 mL Bacteriostatic Water for Injection, USP (with benzyl alcohol) for the 125 mg vial. 4.Agitate to effect solution.
Is benzyl alcohol safe to use in bacteriostatic water?
While benzyl alcohol and its use in bacteriostatic water are presumed to be safe, there are some precautionary rules that we need to consider to responsibly use the solution. Manufacturers and supplying companies like us here at Med Lab Gear will often dictate very specific instructions and warnings regarding bacteriostatic water and its use.
What is the percent alcohol in bacteriostat?
This bacteriostat is usually 0.9% benzyl alcohol. It is only used for injections such as intravenous, intramuscular and subcutaneous. Due to the bacteriostat, bacteriostatic water comes in a multi-dose formulation for multiple uses.
Can I use sterile water instead of bacteriostatic water?
Do not use Bacteriostatic Water for Injection, USP for those products that specify the use of only Sterile Water for Injection, USP as a sterile solvent.
Is it safe to inject bacteriostatic water?
Do not use Bacteriostatic Water (bacteriostatic water (bacteriostatic water for injection) for injection) for Injection, USP for intravenous injection unless the osmolar concentration of additives results in an approximate isotonic admixture.
Can you inject benzyl alcohol?
Abstract. Bacteriostatic saline is a physiological saline solution containing the bacteriostatic agent benzyl alcohol as a 0.9% solution. It is used mostly for diluting and dissolving drugs for IV injection and as a flush for intravascular catheters.
Is 0.9% sodium chloride the same as bacteriostatic water?
Bacteriostatic 0.9% Sodium Chloride Injection, USP is a sterile, nonpyrogenic, isotonic solution of sodium chloride in water for injection. Each milliliter (mL) contains sodium chloride 9 mg and 0.9% (9 mg/mL) benzyl alcohol added as a bacteriostatic preservative. May contain hydrochloric acid for pH adjustment.
Should you refrigerate bacteriostatic water?
There are no special rules that need to be followed as far as discard. Keep your unused bacteriostatic water in the container it arrives in. Store the container in a dark place with a residual, resting room temperature that doesn't exceed 80 degrees Fahrenheit and doesn't drop below 60 degrees Fahrenheit.
How long does bacteriostatic water last in fridge?
Hospira, the world's leading manufacturer and supplier of bacteriostatic and sterile water, recommends that once a vial of bacteriostatic water is open the preservatives will prolong its life for up to 28 days and that after this period of time the vial should to be discarded.
What is benzyl alcohol used for in injections?
Benzyl alcohol is mainly used as an excipient in medicinal products that are administered intramuscularly, such as antibiotics, anti-inflammatory or antipsychotic medicines where its anaesthetic properties reduce pain at the injection site.
How toxic is benzyl alcohol?
Its toxicity is 2–3 times higher than that of isopropanol. The local reactions seen on the skin are flush and irritations, while inhaling may induce vomiting, headache, diarrhea, and/or collapse. The activity of benzyl alcohol on head lice was reported by Meinking et al.
Is benzyl alcohol the same as alcohol?
Abstract. Benzyl Alcohol is an aromatic alcohol used in a wide variety of cosmetic formulations as a fragrance component, preservative, solvent, and viscosity-decreasing agent.
Does Walgreens sell BAC water?
B Braun Sterile Water for Injection bags If you are needing bacteriostatic water for a medication today, you can shop around at various local pharmaceutical retailers, such as Walgreens, CVS, or Walmart.
Is sterile water the same as sodium chloride?
Distilled water is created by a process of steaming and condensation, and does not contain any minerals like salt, calcium or iron. A distinction should further be made between sterile water and saline solution. Sterile Saline solution has 0.9% Sodium Chloride and is used for wound irrigation and cleaning.
Is bacteriostatic saline the same as normal saline?
Both normal saline and bacteriostatic saline are often used as vehicles for the injection of therapeutic drugs. However, their properties differ slightly as a result of the 0.9% benzyl alcohol component of BS.
Can you use bacteriostatic water for Botox?
TIP: Always use bacteriostatic normal saline as the diluent as per manufacturer guidance. Reconstituting with sterile water can cause the client great discomfort during treatment.
When do you use bacteriostatic water injection?
The Bacteriostatic Water can be used in diluting drugs that can subsequently be administered by intravenous, intramuscular, or subcutaneous injection.
Can you use bacteriostatic water to mix Botox?
At Hamilton Facial Plastic Surgery, we mix our Botox using bacteriostatic saline (a sterile, isotonic solution of sodium chloride in water and benzyl alcohol added as a bacteriostatic preservative). I believe in using this mixture because it is thought to be less painful and longer lasting.
Is sterile water for injection containing one or more suitable antimicrobial agents?
Sterile Water for Injection, USP, is sterile, nonpyrogenic, distilled water in a single dose container for intravenous administration after addition of a suitable solute. It may also be used as a dispensing container for diluent use. No antimicrobial or other substance has been added.
DESCRIPTION
The following preparation is designed solely for parenteral use only after addition of drugs that require dilution or must be dissolved in an aqueous vehicle prior to injection.
CLINICAL PHARMACOLOGY
Water is an essential constituent of all body tissues and accounts for approximately 70% of total body weight. Average normal adult daily requirement ranges from two to three liters (1.0 to 1.5 liters each for insensible water loss by perspiration and urine production).
INDICATIONS AND USAGE
This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.
CONTRAINDICATIONS
Due to the potential toxicity of benzyl alcohol in neonates, solutions containing benzyl alcohol must not be used in this patient population.
WARNINGS
Benzyl alcohol, a preservative in Bacteriostatic Water for Injection, USP has been associated with toxicity in neonates. Data are unavailable on the toxicity of other preservatives in this age group. Where water is required for preparing or diluting medications for use in neonates, only preservative-free Sterile Water for Injection should be used.
PRECAUTIONS
Do not use Bacteriostatic Water for Injection, USP for intravenous injection unless the osmolar concentration of additives results in an approximate isotonic admixture.
ADVERSE REACTIONS
Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation.
Hospira Bacteriostatic Water for Injection Supplier
At BacteriostaticWater.com, we’re dedicated to offering the lowest pricing on Hospira Bacteriostatic Water and Sterile Water for Injection as well as exceptional customer support. Located in the United States, we offer extremely competitive pricing and professional packaging for your order.
What is Bacteriostatic Water?
Bacteriostatic Water for Injection is sterile, non-pyrogenic water that contains 0.9% benzyl alcohol (9mg/mL) added as a bacteriostatic preservative. This preparation of sterile water and benzyl alcohol (BnOH) allows repeated withdrawals to be made from a single 30mL plastic vial.
Purchase Bacteriostatic Water, Insulin Syringes and More!
At BacteriostaticWater.com, we offer quality Hospira brand Bacteriostatic Water and Sterile Water for injection for injection to purchase online that has an expiration date exceeding one year. Bacteriostatic Water is a preparation designed solely for parenteral use.
Empty Sterile Sealed Glass Vials
Empty injection vials are sterile, nonpyrogenic vials made with USP Type I glass that are used for mixing different medications or solutions for injection. The sealed top provides easy needle insertion while keeping the injected liquids safely contained for mixing.
Can I Use Sterile Water Instead of Bacteriostatic Water?
This is a common question for those unfamiliar with microbiology, as well as those who may recently have been prescribed medication that requires dilution or solution.
Where Can I Buy Bacteriostatic Water
Bacteriostatic water can be purchased online through various suppliers, Amazon included. However, as a medical professional, I would strongly recommend that you purchase bacteriostatic water directly from a medical supplier or pharmacy.
What Are Some Uses of Bacteriostatic Water?
Bacteriostatic water has many uses besides just in the medical field, though the most common comes with the application of medicine.
Bacteriostatic Water vs. Sterile Water: The Differences That Can Save Your Life
Many people have this mentality that bacteriostatic water and sterile water are the same thing, and that can bring disastrous results. Patients, athletes, healthcare workers and others use sterile solutions to help in medication delivery, injections, irrigation and other uses.
Sterile Water And Purity
Sterile water is purified water that has been distilled and brought to a pH between 5.0 to 7.0. There is no sort of preservative or antimicrobial agent added to it. Sterile water is available for injection use such as intravenous, intramuscular and subcutaneous. A separate formulation is used for irrigation such as washing, rinsing and diluting.
Bacteriostatic Water And Purity
Bacteriostatic water is a sterile form of water that has been brought to a pH between 4.5 to 7.0. It also is prepared with a bacteriostat, a compound used to prevent any bacterial growth. This bacteriostat is usually 0.9% benzyl alcohol. It is only used for injections such as intravenous, intramuscular and subcutaneous.
The Differences That Matter The Most
Let’s nail the major differences right from the start. As mentioned previously, sterile water only has distilled water and nothing else. Bacteriostatic water is water with benzyl alcohol. Immediately you can gauge which is appropriate based on allergies.
Similarities That Overlap In Both Solvents
Both bacteriostatic water and sterile water are not used for straight injections, they have to be diluted with another drug or solvent. Using in such a matter can cause hemolysis or destruction of red blood cells. They both are nonpyrogenic meaning they won’t cause fever.
In Closing
This should hopefully shed some light on an easily confusing topic on which water to use. Definitely be educated on the similarities and differences and have confidence when purchasing. Using either in the proper conditions can provide extraordinary results.
Description
Clinical Pharmacology
Indications and Usage
- This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.
Contraindications
- Due to the potential toxicity of benzyl alcohol in neonates, solutions containing benzyl alcohol must not be used in this patient population. Parenteral preparations with benzyl alcohol should not be used for fluid replacement. Parenteral preparations containing benzyl alcohol should not be used in epidural or spinal anesthesia procedures. Bacteriostatic Water for Injection, USP must b…
Warnings
- Benzyl alcohol, a preservative in Bacteriostatic Water for Injection, USP has been associated with toxicity in neonates. Data are unavailable on the toxicity of other preservatives in this age group. Where water is required for preparing or diluting medications for use in neonates, only preservative-free Sterile Water for Injection should be used. ...
Precautions
- Do not use Bacteriostatic Water for Injection, USP for intravenous injection unless the osmolar concentration of additives results in an approximate isotonic admixture. Consult the manufacturer's instructions for choice of vehicle, appropriate dilution or volume for dissolving the drugs to be injected, including the route and rate of injection. Inspect reconstituted (diluted or di…
Adverse Reactions
- Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation. If an adverse reaction does occur, discontinue the infusion, e…
Overdosage
- Use only as a diluent or solvent. This parenteral preparation is unlikely to pose a threat of fluid overload except possibly in very small infants. In the event these should occur, re-evaluate the patient and institute appropriate corrective measures. See WARNINGS, PRECAUTIONS and ADVERSE REACTIONS.
Dosage and Administration
- The volume of the preparation to be used for diluting or dissolving any drug for injection is dependent on the vehicle concentration, dose and route of administration as recommended by the manufacturer. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.
How Is Bacteriostatic Water For Injection Supplied
- Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Distributed by Hospira, Inc., Lake Forest, IL 60045 USA LAB-0977-2.0 Revised: 08/2019